Bioinformatics and computational biology

Research opportunity for a postdoctoral clinical fellow in Nicholas Luscombe's lab.

Introduction

We are a computational biology laboratory with a particular interest in the genome-scale analysis of gene regulation and evolution. Our goal is to use genomic data to understand:

  • How is gene expression regulated?
  • How do these mechanisms control interesting biological behaviours, including diseases?
  • How does gene regulation affect evolution?

We use a genomic approach as it allows us to identify common principles that apply to most biological systems. Unique or unusual cases - which always occur in biology - could then be understood within this broader context. Most of our work depends on publicly available data, but we also collaborate closely with experimental laboratories.