We are seeking to appoint a physical scientist (preferably with a PhD in Physics or related disciplines) with experience on single molecule nanomechanical experiments applied to proteins. The project will investigate the nanomechanical properties of proteins forming the adherens junctions in epithelial and endothelial tissues. The candidate will join a multidisciplinary group in the Department of Physics of King’s College London working on several aspects of mechanosensing and mechanotransduction from the single molecule level. The project is part of the BBSRC sLOLA consortium, held between the University of Bristol, UCL and King’s College London.
This post will be offered on an a fixed-term contract for 24 months.
This is a full-time post - 100% full time equivalent.
- Develop high quality research in the field of single protein mechanics
- Contribute to publications arising from this project
- ontribute fully to developing and enhancing the research profile of the Department, Faculty, and University, including establishing a track record of high quality publications
- Use new research techniques and methods
- Identify areas for research, develop new research methods and extend the research portfolio
The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.
Skills, knowledge, and experience
- Hold a PhD in Physics, Biophysics, Physical Chemistry or equivalent
- Experience with single molecule nanomechanical experiments (AFM/Magnetic Tweezers/Optical Tweezers).
- Programming skills
- Experience with instrument development
- Experience in student supervision
- Experience in grant writing and project design
- Experience in light (especially confocal) microscopy
- Experience in cell mechanobiology (AFM, tweezers, substrate stiffness…)
- Experience in protein design, cloning, expression and purification
*Please note that this is a PhD level role but candidates who have submitted their thesis and are awaiting award of their PhDs will be considered. In these circumstances the appointment will be made at Grade 5, spine point 30 with the title of Research Assistant. Upon confirmation of the award of the PhD, the job title will become Research Associate and the salary will increase to Grade 6.