Laboratory Research Scientist – Slide-seq Spatial Transcriptomics Platform

Applies specific technical or practical skills and has a well-developed working knowledge of technical or scientific practices and procedures acquired through on-the-job, vocational or academic training. Work will involve the application of skills and knowledge to provide a range of technical support activities.

Key information

Job reference
R248
Salary
Competitive with benefits, subject to skills and experience.
Application close date
02 July 2021, 00:00 BST
Hours per week
36 (full time)
Posted 04 June 2021

Laboratory Research Scientist – Slide-seq Spatial Transcriptomics Platform

Reports to: Head of the Advanced Sequencing Facility

This is a full-time, fixed term (12 months) position on Crick terms and conditions of employment.

Closing date: 2 July 2021, 23:59

         

Summary

Slide-seq is the first spatial transcriptomic technology to provide transcriptome-wide gene expression profiling with single cell spatial resolution. In collaboration with Samuel Rodriques, one of the inventors of Slide-seq and the founder of the Crick’s Applied Biotechnology Laboratory, the Crick is now establishing an internal platform to assist its laboratories in adopting Slide-seq to answer a variety of biological questions. This position is for a fixed-term      Laboratory Research Scientist (     LRS) to lead the operation of the Crick’s Slide-seq platform. The postholder will be housed within the      Advanced Sequencing Facility and will have the opportunity to support other research projects using a wide range of genomics applications, from receiving samples, through quality control checking, library preparation and sequencing.

Key responsibilities    

The postholder’s key responsibilities include, but are not limited to:

  • Operating the Slide-seq sequencing equipment, to produce arrays that Crick scientists can use for their Slide-seq experiments.
  • Liaising with Crick laboratories and scientists to explain to them how Slide-seq works and how it can be used in their experiments.
  • Helping potential users to plan their Slide-seq experiments.
  • Teaching users how to run Slide-seq experiments.
  • Helping users to analyse their Slide-seq data.
  • Management of the Slide-seq equipment, lab, instruments and supplies on a daily basis.
  • Keeping accurate laboratory records both on paper and electronically
  • Support diverse research projects across the Institute using next generation sequencing technologies

Key experience and competencies

The post holder should embody and demonstrate our core Crick values: bold, imaginative, open, dynamic and collegial, in addition to the following:

Essential

  • Higher education degree in bioengineering, molecular biology or similar
  • Experience with next-generation sequencing
  • Experience with microscopy
  • Excellent organisational skills  including thorough record-keeping
  • Strong collaborative ability and teamwork experience
  • Good interpersonal skills enabling the postholder to build effective relationships both within their team and in collaboration with colleagues
  • Strong communication skills enabling the postholder to train and support colleagues effectively

Desirable

  • Experience with programming, especially in python
  • Experience with fluidics