Applications are invited for a postdoctoral research fellow position in UCL Division of Infection and Immunity in a research team led by Dr Paola Bonfanti currently based at the Francis Crick Institute.
The post is funded by a Cystic Fibrosis (CF) Trust Consortium grant entitled "Therapeutic gene editing of CFTR".
The overall aims of this collaborative research project are to develop gene editing therapies for cystic fibrosis with complementary strategies:
- the development of direct delivery of CRISPR/Cas9 constructs in nanoparticle formulations to cells of the human airway for a cell and gene-therapy approach in regeneration models and
- characterising human airway stem cells by understanding the underlying molecular and cellular mechanisms that regulate epithelia self-renewal and differentiation, with the final goal to produce long lasting, medicinal products.
The postholder will be expected to perform the highest quality research under the direction of the Principal Investigator, and to work effectively with external collaborators involved in the project and other group members.
Dr Bonfanti directs an interdisciplinary team, including molecular biologists, biochemists, immunologists, clinicians and a microsurgeon.
The post will suit a motivated postdoctoral scientist who wishes to develop their career and pursue opportunities for independent fellowships.
Please see the lab's website for further background information.
The position is available for one year in the first instance with the possibility of extension up to three years.
The postholder should have (or be about to be awarded) a PhD in a relevant subject. The successful candidate must have significant experience of working in a research laboratory.
Evidence of scientific contribution including publications and presentation at conferences is also essential. Candidates must have excellent oral and written scientific communications skills, commitment to collaboration in research and to taking a multidisciplinary approach to problem solving.
Note: Appointment at grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at the research assistant Grade 6B (salary £32,217 - £33,958 per annum) with payment at Grade 7 being backdated upon the final submission of the PhD thesis.
A job description and person specification can be accessed on the UCL website.
If you have any queries regarding the application process, please contact Isabel Lubeiro by email at firstname.lastname@example.org.