Laboratory Research Scientist
This is a 6-month position
The Francis Crick Institute is a world-leading centre of biomedical research and innovation. It promotes connections between researchers and disciplines and between academic institutions, healthcare organisations and businesses. Dedicated to research excellence, the institute has the scale, vision and expertise to tackle the most challenging scientific questions underpinning health and disease. It is world-class with a strong national role—training scientists and developing ideas for public good.
A 6-month position of Laboratory Research Scientist has been created to support research on epigenetic mechanisms important for cancer development within the Scaffidi Laboratory.
- To work in collaboration with other members of the group and support ongoing projects in the laboratory. We use a range of molecular and cellular approaches, including CRISPR-based genetic methods, to understand how epigenetic deregulation promotes malignant phenotypes (Torres et al. Science 2016, Monserrat et al. Nature Cell Biology 2021, Chakrabarti et al. Molecular Cell 2019).
The post holder should embody and demonstrate our core Crick values: Bold, Imaginative, Open, Dynamic and Collegial, in addition to the following:
- BSc in Biochemistry, Cell Biology, Natural Science or related disciplines and at least 1yr of relevant laboratory experience.
- Proficiency in basic laboratory techniques such as cell culture, PCR, genomic DNA extraction, qRT-PCR, molecular cloning and microscopy
- M.res or PhD in a relevant discipline
- Good knowledge of epigenetics and gene expression regulation
- Experience with quantitative microscopy
- Experience with mouse embryonic stem cells
- Experience with bioinformatic analysis
The post holder will be trained in all specific techniques by a Principal Laboratory Scientist and will receive support by the rest of the lab and the Crick core facilities.
Informal enquiries relating to this role can be addressed to Paola Scaffidi: Paola.Scaffidi@crick.ac.uk