Postdoctoral Training Fellow - Goehring Lab

Postdoctoral Training Fellows are expected to lead their own projects and collaborate within the lab and externally. The ability to work in a team is essential.

Key information

Job reference
From £40,125 per annum, subject to skills and experience
Hours per week
36 (full time)
Posted 09 December 2022
Background texture taken from the lab imagery.

Postdoctoral Training Fellow NW Goehring lab

Reporting to: Nathan Goehring, Senior Group Leader

Contact term: This is a full-time, fixed term (4 years) position on Crick terms and conditions of employment.

Please note this is a rolling advert with no specific closing date. Applications will be considered as they arrive and will close once the position is filled.

Anticipated starting date of Summer 2023, though flexibility is possible.

The Research Group

Work in the Goehring lab aims to understand how cell polarity is established by polarity networks that transduce symmetry-breaking cues into stable molecular asymmetries. Our work focuses on a conserved polarity network defined by the PAR (PAR-titioning defective) proteins, which underlie polarity in diverse contexts, including defining epithelial architecture and function, driving asymmetric division of stem cells, and specifying cell fate of embryonic blastomeres.

Using the C. elegans embryo as a model, our interdisciplinary team combines genetics, quantitative imaging, in vivo biophysics, and mathematical modelling to link system-level properties of the PAR network to molecular behaviours, thereby providing a multi-scale model for how PAR proteins polarize cells in response to developmental cues and ultimately how polarized patterns are read out by the downstream pathways that define a cell's functional polarity. For more detail, please see our website.

Position Summary

We aim to recruit a talented and motivated Postdoctoral Training Fellow to join our group. Postdoctoral Training Fellows are expected to lead their own projects, to generate and pursue independent research ideas, and to contribute to other projects on a collaborative basis (both in the lab and with external collaborators). A variety of potential projects are available. The specific project will be developed together with the successful candidate with consideration of their specific interests and experience.

Some examples of current projects include:

  • Modeling and manipulating PAR network feedback circuits
  • Quantitative exploration of kinase-substrate interactions in polarity networks
  • Coupling of mechanical and biochemical networks during cell polarization
  • Cell cycle control of cell polarity and fate specification pathways
  • Canalization of developmental variability during embryogenesis
  • Mechanisms for encoding cellular memory

Note this is a core-funded position, though successful candidates will be encouraged to pursue external fellowship support.

We welcome applications from diverse backgrounds who can bring new ideas, tools, and/or perspectives to the group.

Informal inquiries to Please include a clear statement of why you are interested and how you see yourself contributing to our group.

Key experience and competencies

The post holder should embody and demonstrate our core Crick values: bold, open and collegial, in addition to the following:


  • PhD (awarded or expected) in Cell and Developmental Biology, Biochemistry, Biophysics or similar. Applicants from Physics, Computer Science or Engineering backgrounds seeking to expand their skills in the context of a combined wet/dry project are also welcome to apply.
  • A demonstrated ability to generate and pursue independent research ideas
  • A demonstrated ability to work as part of an interdisciplinary team
  • Willingness to mentor junior members of the laboratory
  • Strong communication and presentation skills
  • Strong organisational and record-keeping skills
  • Track record of scientific scholarship, evidenced by preprints, publications or submitted manuscripts in refereed journals

About Us

At the Crick, we conduct research at the forefront of biomedical research. We combine rigour with an open and collaborative culture, and are outward-looking, reflecting our status as a partnership of six organisations aiming to pool knowledge, ideas and resources.

We have a wide research portfolio with no divisions or departments, bringing biomedical researchers together with clinicians, physical scientists and applied scientists from our pharmaceutical partners.

We aim to attract the most talented researchers and support them to tackle innovative research questions. Our science technology platforms provide our researchers with access to state-of-the-art technology and expertise.

We provide an excellent learning environment with dedicated education programmes in public engagement with science, education and personal development, and a postdoc training programme that prepares scientists for leadership roles in science.

  • If you are interested in applying for this role, please apply via Workday.
  • All offers of employment are subject to successful security screening and continuous eligibility to work in the United Kingdom.
  • If you require a visa to work in the UK we will help support your application should you be successful