Senior Microfluidics Research Scientist and Engineer

In the Crick's Stp |Making Stp.

Deadline for applications has passed.

Key information

Job reference
R1291
Salary
From £43,500 with benefits, subject to skills and experience
Applications closed
28 September 2023, 23:59 BST
Hours per week
36 (full time)
Posted 14 September 2023

Senior Microfluidics Research Scientist and Engineer –

Making Lab Science Technology Platform

Reports to: Head of Making Lab STP

This is a full-time, permanent position on Crick terms and conditions of employment.

           

The Making Lab is a Science Technology Platform (STP) working at the interface of engineering and biology with a multidisciplinary team. We combine approaches from engineering and biomedical research to develop innovative devices and help answer complex research questions. Working in collaboration with Crick’s groups across key areas of research in Cancer, Development, Immunology, Infectious Disease, Neuroscience, Structural Biology, and Bioengineering, our aim is to support the development of biomedical projects with a strong technological focus. Within the state-of-the-art  research facilities at the Crick, the Making Lab provides support and training in three main areas: Microfluidics and Biomaterials, Electronics and Optics, Mechanics and Manufacturing.

The Making Lab aims to be a creative and collaborative space, working closely with Crick groups, other STPs and partner universities to exchange skills, ideas, and techniques. As part of the global Making in Research culture, we believe it is fundamental to bring world class innovative prototyping and programming methods, as well as training scientists in DIY rapid prototyping.

Role summary

We are seeking a bold, open, and collegial individual to manage DIY and collaborative microfluidics and biomaterial projects within the Making Lab at the Francis Crick Institute.

The successful candidate will engineer innovative microfluidic systems for quantitative cell/tissue behaviour studies in well-defined and controlled 3D environments. Practically, the selected candidate will be responsible for the development of microfluidic systems: design, fabrication, flow simulation and analysis, characterisation, experimental validation, integration, writing of scripts to automate fluidic systems and other hardware component, iterative improvement loops for system optimisation. This role will encompass the application of various design and engineering resources available at the platform such as 2D and 3D modelling, CAM, micromanufacturing, photolithography and soft lithography, moulding, biomaterial and bioprinting, flow control and imaging.

The role is ideally suited for a creative individual with a strong interest in technology development and the ambition to independently drive forward projects. The candidate will provide expertise and support to Crick’s groups for their research, lead projects for technological development in the STP and train users of the STP on DIY access. The candidate will work closely with multiple groups and STPs as well as the translation team within the Crick, providing rich opportunities for further scientific and professional development.

The successful applicant will be expected to show great collaboration skills, combined with the passion to develop new approaches, challenge ideas, and iterate quickly to deliver outstanding support to Crick groups and STPs.

Key responsibilities

  • Implement microfluidic approaches to build bespoke systems for real-time feedback experiments.
  • Provide high quality service and support for the microfluidics and biomaterial activity in close collaboration with the Making Lab team.
  • Provide experimental data and research analysis to support the development of a range of products and applications.
  • Initiate, develop, and lead, on the STP side, projects in collaboration with Crick’s labs, reporting regularly to the head of Making lab and the Group Leader.
  • Manage projects independently to ensure the aims are achieved with appropriate quality standards, timescales and cost, and key stakeholders are kept informed.     
  • Contribute to the dissemination of scientific results by means of writing papers for publication, presenting orally and in poster form at external meetings, and making them available on the STP Open Access platform.
  • Teaching and training of Crick researchers on our variety of equipment related to their area of expertise. Running inductions to introduce new Francis Crick staff (e.g. PhD students).
  • Attend and present results at lab meetings. Report on a regular basis to the head of Making Lab. Contribute to the broader range of activities within the Making Lab.
  • Maintenance of significant up-to-date knowledge of relevant literature, communication of key developments to other lab members and the institute, implementation of new techniques to own research.
  • Provide research advice and assist other colleagues in project scoping, technical choice, make vs. buy decisions, sustainability planning.

Key experience and competencies

Essential:

  • Engineering degree or PhD in life science, bioengineering OR equivalent level of experience in these fields.
  • Extensive experience in microfluidic systems development.
  • Experience in model validation (simulation, characterisation).
  • Understanding the requirement of a microfluidic system to function with biological models.
  • Excellent inter-personal skills and commitment to teamwork.
  • Ability to understand different user needs and provide high quality service.
  • Outstanding organisational skills, able to balance multiple activities in parallel ranging from technology support, equipment management, procurement to teaching and training.
  • The candidate must demonstrate an open-minded approach to new directions and developments in the life sciences with the ability to carry out goal driven technological development projects, whilst maintaining an excellent level of support to institute researchers.
  • Experience with data-driven process optimisation.

Desirable:

  • Experience in bioprinting.
  • Experience in biomaterials-based models development.