Science news: 2018

Jan | Feb | Mar | Apr | May | Jun | Jul

New method reveals how well cancer drugs hit their targets

Scientists have developed a technique that allows them to measure how well cancer drugs reach their targets inside the body.
12 July 2018

Genes linking Alzheimer’s and Down syndrome discovered

Scientists are a step closer to understanding which genes are responsible for early onset Alzheimer’s disease in people with Down syndrome.
26 June 2018

Blood signature could improve early TB diagnosis

A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin.
19 June 2018

Genetic discovery could help clinicians identify aggressive bone tumours

Scientists have discovered the first genetic marker for osteoblastoma bone tumours.
15 June 2018

Non-coding DNA changes the genitals you're born with

Male mice grow ovaries instead of testes if they are missing a small region of DNA that doesn’t contain any genes.
14 June 2018

Scientists unravel molecular mechanisms of Parkinson’s disease

Detailed brain cell analysis has helped researchers uncover new mechanisms thought to underlie Parkinson's disease.
12 June 2018

Scientific 'dream team' shed light on motor neuron death

We caught up with the scientists involved in a new collaborative study to find out how working together helped them uncover the earliest events in motor neuron disease.
25 May 2018

How a TB expert found a potential cause of Parkinson’s disease

Max Gutierrez tells us what it’s like to be a TB researcher pushing the boundaries of Parkinson’s research.
25 May 2018

Link between tuberculosis and Parkinson’s disease discovered

The mechanism our immune cells use to clear bacterial infections like tuberculosis (TB) might also be implicated in Parkinson’s disease, according to a new collaborative study.
22 May 2018

New lab study reveals how breast cancer drug can accelerate cancer cell growth

The breast cancer drug lapatinib which is designed to shrink tumours can sometimes cause them to grow in the lab.
01 May 2018

Working together to unravel the immune system’s secrets

As Associate Research Director, Professor Anne O'Garra helps to promote the Crick's collaborative vision, encouraging scientists from different disciplines to work together. But when it comes to her own research, does she practice what she preaches? We examine the story behind her latest publication in Nature Immunology.
17 April 2018

From patient to paper: how tumour donations help Crick scientists understand cancer

Mike Malley, 72, was diagnosed with a type of kidney cancer called renal cell carcinoma in February 2015. Whilst undergoing treatment, he signed up to a Cancer Research UK funded study called Renal TRACERx (Tracking Cancer Evolution through therapy) that looks at the evolution of kidney cancer to try and better predict tumour behaviour, in the hope of improving treatments in the future.
13 April 2018

'Killer' kidney cancers identified by studying their evolution

Scientists have discovered that kidney cancer follows distinct evolutionary paths, enabling them to detect whether a tumour will be aggressive.
12 April 2018

From frogspawn to frog: understanding how organisms develop

Jim Smith's Developmental Biology lab at the Crick have recently uncovered two new insights into development in Xenopus frogs, deepening our understanding of the mechanisms that support this crucial process.
23 March 2018

Placenta defects a factor in prenatal deaths

The role of the placenta in healthy fetal development is being seriously under-appreciated, according to new research.
14 March 2018

Scientists find new antimalarial drug targets

Researchers have discovered crucial new processes that allow malaria parasites to escape red blood cells and infect other cells, offering potential new treatment targets.
20 February 2018

Research reveals how our brains develop the right mix of cells

Research reveals how our brains develop the right mix of cells
13 February 2018

Molecular ‘magnets’ could improve cancer immunotherapy

Molecular ‘magnets’ could improve cancer immunotherapy
08 February 2018

Research uncovers gene network that regulates motor neuron formation during embryonic development

Scientists have uncovered the inner workings of a gene network that regulates the development of spinal motor neurons in the growing embryo.
02 February 2018

Newly-discovered TB blood signal provides early warning for at-risk patients

Tuberculosis can be detected in people with HIV infection via a unique blood signal before symptoms appear.
17 January 2018

New method to map miniature brain circuits

In a feat of nanoengineering, scientists have developed a new technique to map electrical circuits in the brain far more comprehensively than ever before.
12 January 2018