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Breadcrumb Steve Gamblin Gamblin lab Structural Biology of Disease Processes Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Structures of proteins investigated in the Gamblin lab: AMPK, PRC2 and influenza hemagglutinin (left to right). Toggle to view hero caption PublicationsYear published (-)2020 (12) Facet Year publishedResearch topicsCell Cycle & Chromosomes (12)Infectious Disease (12)Metabolism (12)Structural Biology & Biophysics (12)Chemical Biology & High Throughput (9)Cell Biology (8)Model Organisms (7)Computational & Systems Biology (5)Genetics & Genomics (5)Human Biology & Physiology (5)Imaging (5)Genome Integrity & Repair (4)Neurosciences (4)Signalling & Oncogenes (4)Stem Cells (4)Tumour Biology (4)Immunology (3)Biochemistry & Proteomics (2)Developmental Biology (1)Gene Expression (1)Microfabrication & Bioengineering (1)Synthetic Biology (1) Facet Research topicsPublication typeJournal article (12)Primary research (8)Case report (1)Letter (1)Method (1)Review (1) Facet Publication typeJournalNature (2)The Lancet (2)Cell Host and Microbe (1)Cold Spring Harbor Perspectives in Medicine (1)Europace (1)Nature Biotechnology (1)Nature Communications (1)Nature Genetics (1)Nature Structural & Molecular Biology (1)Science (1) Facet Journal Publications Displaying 1 - 12 of 12Last updated : 19 April 2024 03:58 Preexisting and de novo humoral immunity to SARS-CoV-2 in humans Authors (47)Kevin NgNikhil Faulkner Georgina H CornishAnnachiara Rosa Ruth HarveySaira Hussain[...]Steve Gamblin Laura E MccoyPeter Cherepanov Eleni NastouliGeorge Kassiotis Science Published 11 December 2020 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeWorldwide Influenza CentreStructural BiologyFlow CytometryHigh Throughput ScreeningCell ServicesFull details Misuse of SARS-CoV-2 testing in symptomatic health-care staff in the UK – Authors' reply Authors (8) James RM Black Chris BaileyAska PrzewrockaKrijn DijkstraSonia GandhiSteve GamblinSam BarrellCharles Swanton The Lancet Published 24 October 2020 Crick labsCharles SwantonSonia GandhiSteve GamblinFull details Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein Authors (9)Antoni WrobelDonald BentonSaira Hussain Ruth Harvey Stephen R MartinChloe RoustanPeter Rosenthal John J SkehelSteve Gamblin Nature Communications Published 21 October 2020 Crick labs/ facilitiesPeter RosenthalNicola LewisSteve GamblinWorldwide Influenza CentreStructural BiologyScientific computingFull details Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option Authors (9)Kevin NgJan Attig William BollandGeorge YoungJack MajorAntoni WrobelSteve GamblinAndreas WackGeorge Kassiotis Nature Genetics Published 1 December 2020 Crick labs/ facilitiesAndreas WackJonathan StoyeGeorge KassiotisSteve GamblinScientific computingFlow CytometryCell ServicesAdvanced SequencingFull details Hemagglutinin traits determine transmission of avian A/H10N7 influenza virus between mammals Authors (20) Sander HerfstJie Zhang Mathilde Richard Ryan McBride Pascal Lexmond Theo M Bestebroer[...] Erhard van der Vries Albert DME Osterhaus James C Paulson John J Skehel Ron AM Fouchier Cell Host and Microbe Published 7 October 2020 Crick labs/ facilitiesSteve GamblinStructural BiologyFull details Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion Authors (8)Donald BentonAntoni Wrobel Pengqi XuChloe Roustan Stephen R MartinPeter Rosenthal John J SkehelSteve Gamblin Nature Published 10 December 2020 Crick labs/ facilitiesPeter RosenthalSteve GamblinStructural BiologyScientific computingFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects Authors (8)Antoni WrobelDonald Benton Pengqi XuChloe Roustan Stephen R MartinPeter Rosenthal John J SkehelSteve Gamblin Nature Structural & Molecular Biology Published 1 August 2020 Crick labs/ facilitiesPeter RosenthalSteve GamblinStructural BiologyScientific computingFull details Scalable and robust SARS-CoV-2 testing in an academic center Authors (81) Jim Aitken Karen Ambrose Sam BarrellRupert Beale Ganka Bineva-Todd Dhruva Biswas[...]Sophie Ward Wai Keong WongJoshua Wright Mary Wu The Crick COVID-19 Consortium Nature Biotechnology Published 1 August 2020 Crick labs/ facilitiesAndreas WackJames TurnerCharles SwantonCaetano Reis e SousaPeter RatcliffeVenizelos PapayannopoulosGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeStructural BiologyMetabolomicsHigh Throughput ScreeningGenetic Modification ServiceFermentationBiological Research FacilityAdvanced SequencingScientific computingFull details Hemagglutinin structure and activities Authors (6)Steve Gamblin Sébastien G Vachieri Xiaoli XiongJie Zhang Stephen R Martin John J Skehel Cold Spring Harbor Perspectives in Medicine Published 1 October 2021 Crick labs/ facilitiesSteve GamblinStructural BiologyFull details Structural transitions in influenza haemagglutinin at membrane fusion pH Authors (4)Donald BentonSteve GamblinPeter Rosenthal John J Skehel Nature Published 2 July 2020 Crick labs/ facilitiesPeter RosenthalSteve GamblinStructural BiologyScientific computingFull details Sudden death associated with a novel H401Q PRKAG2 mutation Authors (7) Maria Helena Albernaz Siqueira Kinulpe Honorato-Sampaio Glauber Monteiro DiasJon Wilson Arash Yavari Geraldo Brasileiro Filho Eduardo Back Sternick Europace Published 1 August 2020 Crick labsSteve GamblinFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Preexisting and de novo humoral immunity to SARS-CoV-2 in humans Authors (47)Kevin NgNikhil Faulkner Georgina H CornishAnnachiara Rosa Ruth HarveySaira Hussain[...]Steve Gamblin Laura E MccoyPeter Cherepanov Eleni NastouliGeorge Kassiotis Science Published 11 December 2020 Crick labs/ facilitiesCharles SwantonGitta StockingerNicola LewisGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeWorldwide Influenza CentreStructural BiologyFlow CytometryHigh Throughput ScreeningCell ServicesFull details
Misuse of SARS-CoV-2 testing in symptomatic health-care staff in the UK – Authors' reply Authors (8) James RM Black Chris BaileyAska PrzewrockaKrijn DijkstraSonia GandhiSteve GamblinSam BarrellCharles Swanton The Lancet Published 24 October 2020 Crick labsCharles SwantonSonia GandhiSteve GamblinFull details
Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein Authors (9)Antoni WrobelDonald BentonSaira Hussain Ruth Harvey Stephen R MartinChloe RoustanPeter Rosenthal John J SkehelSteve Gamblin Nature Communications Published 21 October 2020 Crick labs/ facilitiesPeter RosenthalNicola LewisSteve GamblinWorldwide Influenza CentreStructural BiologyScientific computingFull details
Tissue-specific and interferon-inducible expression of nonfunctional ACE2 through endogenous retroelement co-option Authors (9)Kevin NgJan Attig William BollandGeorge YoungJack MajorAntoni WrobelSteve GamblinAndreas WackGeorge Kassiotis Nature Genetics Published 1 December 2020 Crick labs/ facilitiesAndreas WackJonathan StoyeGeorge KassiotisSteve GamblinScientific computingFlow CytometryCell ServicesAdvanced SequencingFull details
Hemagglutinin traits determine transmission of avian A/H10N7 influenza virus between mammals Authors (20) Sander HerfstJie Zhang Mathilde Richard Ryan McBride Pascal Lexmond Theo M Bestebroer[...] Erhard van der Vries Albert DME Osterhaus James C Paulson John J Skehel Ron AM Fouchier Cell Host and Microbe Published 7 October 2020 Crick labs/ facilitiesSteve GamblinStructural BiologyFull details
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion Authors (8)Donald BentonAntoni Wrobel Pengqi XuChloe Roustan Stephen R MartinPeter Rosenthal John J SkehelSteve Gamblin Nature Published 10 December 2020 Crick labs/ facilitiesPeter RosenthalSteve GamblinStructural BiologyScientific computingFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects Authors (8)Antoni WrobelDonald Benton Pengqi XuChloe Roustan Stephen R MartinPeter Rosenthal John J SkehelSteve Gamblin Nature Structural & Molecular Biology Published 1 August 2020 Crick labs/ facilitiesPeter RosenthalSteve GamblinStructural BiologyScientific computingFull details
Scalable and robust SARS-CoV-2 testing in an academic center Authors (81) Jim Aitken Karen Ambrose Sam BarrellRupert Beale Ganka Bineva-Todd Dhruva Biswas[...]Sophie Ward Wai Keong WongJoshua Wright Mary Wu The Crick COVID-19 Consortium Nature Biotechnology Published 1 August 2020 Crick labs/ facilitiesAndreas WackJames TurnerCharles SwantonCaetano Reis e SousaPeter RatcliffeVenizelos PapayannopoulosGeorge KassiotisSonia GandhiSteve GamblinPeter Cherepanov Rupert BealeStructural BiologyMetabolomicsHigh Throughput ScreeningGenetic Modification ServiceFermentationBiological Research FacilityAdvanced SequencingScientific computingFull details
Hemagglutinin structure and activities Authors (6)Steve Gamblin Sébastien G Vachieri Xiaoli XiongJie Zhang Stephen R Martin John J Skehel Cold Spring Harbor Perspectives in Medicine Published 1 October 2021 Crick labs/ facilitiesSteve GamblinStructural BiologyFull details
Structural transitions in influenza haemagglutinin at membrane fusion pH Authors (4)Donald BentonSteve GamblinPeter Rosenthal John J Skehel Nature Published 2 July 2020 Crick labs/ facilitiesPeter RosenthalSteve GamblinStructural BiologyScientific computingFull details
Sudden death associated with a novel H401Q PRKAG2 mutation Authors (7) Maria Helena Albernaz Siqueira Kinulpe Honorato-Sampaio Glauber Monteiro DiasJon Wilson Arash Yavari Geraldo Brasileiro Filho Eduardo Back Sternick Europace Published 1 August 2020 Crick labsSteve GamblinFull details