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Breadcrumb Caetano Reis e Sousa Reis e Sousa lab Immunobiology Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies News Alumni Dendritic cells are white blood cells that get their name from their tree-like shape (dendron is the Greek word for tree). 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(4)Journal of Immunology (4)Nature (4)Nature Immunology (4)Science (4)Current Opinion in Immunology (3)eLife (3)Science Immunology (3)Annual Review of Immunology (2)Blood (2)Journal of Clinical Investigation (2)Nature Communications (2)Seminars in Immunology (2)BioEssays (1)Cell Host & Microbe (1)Cell Stem Cell (1)Current Opinion in Microbiology (1)Developmental Cell (1)EMBO Molecular Medicine (1)ESMO Open (1)European Journal of Clinical Investigation (1)Frontiers in Immunology (1)Immunological Reviews (1)Journal for ImmunoTherapy of Cancer (1)Journal of Experimental Medicine (1)Methods in Molecular Biology (1)Nature Biotechnology (1)Oncoimmunology (1)Open Biol (1)PLOS Pathogens (1)Proceedings of the National Academy of Sciences of the United States of America (1)The EMBO Journal (1)The Lancet (1)Trends in Cancer (1)Trends in Immunology (1)Wellcome Open Research (1) Facet Journal Publications Displaying 1 - 20 of 95Last updated : 19 April 2024 02:34 Myeloid C-type lectin receptors in innate immune recognition Authors (3)Caetano Reis e Sousa Sho Yamasaki Gordon D Brown Immunity Published 9 April 2024 Crick labsCaetano Reis e SousaFull details Distinct ontogenetic lineages dictate cDC2 heterogeneity Authors (15)Carlos Munoz MinuttiCecile PiotMariana Pereira Da Costa Probir ChakravartyNeil RogersHector Huerga Encabo[...] Jean LanghorneDominique Bonnet Marc Dalod Elena TomaselloCaetano Reis e Sousa Nature Immunology Published 1 March 2024 Crick labs/ facilitiesCaetano Reis e SousaJean LanghorneGeorge KassiotisDominique BonnetBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells Authors (15)Conor Henry Carlos A CastellanosMichael BuckEvangelos GiampazoliasBruno FredericoAna Matos Cardoso Da Silva[...]Peter FaullBram Snijders Bhopal Mohapatra Hamid BandCaetano Reis e Sousa Cell Reports Published 26 December 2023 Crick labs/ facilitiesCaetano Reis e SousaProteomicsFlow CytometryBiological Research FacilityFull details Endothelial AHR activity prevents lung barrier disruption in viral infection Authors (13)Jack MajorStefania CrottaKatja Finsterbusch Probir ChakravartyKathleen ShahBruno Frederico[...] Lucy Meader Alejandro Suarez-BonnetSimon PriestnallBrigitta StockingerAndreas Wack Nature Published 28 September 2023 Crick labs/ facilitiesAndreas WackGitta StockingerCaetano Reis e SousaLight MicroscopyExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details Interplay between CXCR4 and CCR2 regulates bone marrow exit of dendritic cell progenitors Authors (11)Mariana Pereira Da CostaCarlos Munoz MinuttiCecile PiotEvangelos GiampazoliasAna Matos Cardoso Da SilvaMaria Del Mar Cabeza CabrerizoNeil RogersMarta de Lebrusant FernandezChrysante IliakisAndreas WackCaetano Reis e Sousa Cell Reports Published 29 August 2023 Crick labs/ facilitiesAndreas WackCaetano Reis e SousaPatricia BarralFlow CytometryBiological Research FacilityFull details Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils Authors (22)Hector Huerga EncaboIker Valle AramburuManuel Garcia AlbornozMarion Piganeau Henry Wood Anna Song[...] Daniel H Wiseman Kiran Batta Rajeev GuptaVenizelos PapayannopoulosDominique Bonnet Cell Stem Cell Published 1 June 2023 Crick labs/ facilitiesCaetano Reis e SousaVenizelos PapayannopoulosDominique BonnetLight MicroscopyElectron MicroscopyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details The dietary sweetener sucralose is a negative modulator of T cell-mediated responses Authors (16)Fabio ZaniJulianna Blagih Tim GruberMichael Buck Nicholas JonesMarc Hennequart[...]Eric Cheung Ian S GilmoreAlex Gould Cristina Garcia-CaceresKaren Vousden Nature Published 23 March 2023 Crick labs/ facilitiesKaren VousdenCaetano Reis e SousaAlex GouldMetabolomicsBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details In vivo analysis of dendritic cell clonality Authors (1)Maria Del Mar Cabeza Cabrerizo Methods in Molecular Biology Published 12 March 2023 Crick labs/ facilitiesCaetano Reis e SousaLight MicroscopyFlow CytometryBiological Research FacilityFull details DNGR-1-mediated cross-presentation of dead cell-associated antigens Authors (3)Conor Henry Carlos A CastellanosCaetano Reis e Sousa Seminars in Immunology Published 7 February 2023 Crick labsCaetano Reis e SousaFull details Loss of secreted gelsolin enhances response to anticancer therapies Authors (8)Jonathan LimEvangelos GiampazoliasOliver SchulzNeil Rogers Anna WilkinsErik Sahai Jessica StridCaetano Reis e Sousa Journal for ImmunoTherapy of Cancer Published 26 September 2022 Crick labs/ facilitiesErik SahaiCaetano Reis e SousaBiological Research FacilityFull details DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential Authors (17)Bruno Frederico Isaura Martins Diana ChapelaFrancesca Gasparrini Probir ChakravartyTobias Ackels[...]James BriscoeFrancois GuillemotAndreas Schaefer Leonor SaúdeCaetano Reis e Sousa Developmental Cell Published 22 August 2022 Crick labs/ facilitiesAndreas SchaeferCaetano Reis e SousaFrancois GuillemotJames BriscoeLight MicroscopyExperimental HistopathologyElectron MicroscopyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency Authors (8) Jorn E Stok Timo Oosenbrug Laurens R ter Haar Dennis Gravekamp Christian P Bromley Santiago ZelenayCaetano Reis e Sousa Annemarthe G van der Veen The EMBO Journal Published 15 March 2022 Crick labsCaetano Reis e SousaFull details The impact of COVID-19 on oncology professionals-one year on: lessons learned from the ESMO Resilience Task Force survey series Authors (17) KHJ Lim K Murali E Thorne K Punie K Kamposioras C Oing[...] CB Westphalen G Morgan JBAG Haanen C Hardy S Banerjee ESMO Open Published 1 February 2022 Crick labsCaetano Reis e SousaFull details Epithelial colonization by gut dendritic cells promotes their functional diversification Authors (23) Claudia A Rivera Violaine Randrian Wilfrid Richer Yohan Gerber-Ferder Maria-Graciela Delgado Aleksandra S Chikina[...] Hélène D Moreau Julie Helft Danijela Matic Vignjevic Eduardo J Villablanca Ana-Maria Lennon-Duménil Immunity Published 11 January 2022 Crick labsCaetano Reis e SousaFull details Maintenance and loss of endocytic organelle integrity: mechanisms and implications for antigen cross-presentation Authors (4)Eleanor ChildsConor Henry Johnathan CantonCaetano Reis e Sousa Open Biol Published 10 November 2021 Crick labsCaetano Reis e SousaFull details Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity Authors (18)Maria Del Mar Cabeza CabrerizoCarlos Munoz Minutti Mariana Pereira da CostaAna Matos Cardoso Da SilvaRob JenkinsJustina Kulikauskaite[...] Judith E Allen Manolis PasparakisAndreas WackErik SahaiCaetano Reis e Sousa Science Immunology Published 5 November 2021 Crick labs/ facilitiesAndreas WackErik SahaiCaetano Reis e SousaNicola LewisDominique BonnetWorldwide Influenza CentreFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsFull details From mRNA sensing to vaccines Authors (9) Anthony S Fauci Miriam Merad Soumya Swaminathan Sun Hur Eric Topol Kate FitzgeraldCaetano Reis e Sousa Kizzmekia S Corbett Stefan Bauer Immunity Published 14 December 2021 Crick labsCaetano Reis e SousaFull details An isoform of Dicer protects mammalian stem cells against multiple RNA viruses Authors (10)Enzo PoirierMichael Buck Probir ChakravartyJoana Do Vale Viegas Silva CarvalhoBruno FredericoAna Matos Cardoso Da SilvaLyn HealyRachel UlfertsRupert BealeCaetano Reis e Sousa Science Published 9 July 2021 Crick labs/ facilitiesCaetano Reis e SousaRupert BealeHuman Embryonic Stem CellExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryAdvanced SequencingFull details Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity Authors (17)Evangelos GiampazoliasOliver SchulzJonathan LimNeil Rogers Probir Chakravarty Naren Srinivasan[...] Stefano Sammicheli Natalia MoncautSunita Varsani-BrownIan RosewellCaetano Reis e Sousa Cell Published 22 July 2021 Crick labs/ facilitiesCaetano Reis e SousaGenetic Modification ServiceBiological Research FacilityBioinformatics and BiostatisticsFlow CytometryFull details Dendritic cells revisited Authors (5)Maria Del Mar Cabeza CabrerizoAna Matos Cardoso Da SilvaCarlos Munoz MinuttiMariana Pereira Da CostaCaetano Reis e Sousa Annual Review of Immunology Published 1 April 2021 Crick labsCaetano Reis e SousaFull 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Myeloid C-type lectin receptors in innate immune recognition Authors (3)Caetano Reis e Sousa Sho Yamasaki Gordon D Brown Immunity Published 9 April 2024 Crick labsCaetano Reis e SousaFull details
Distinct ontogenetic lineages dictate cDC2 heterogeneity Authors (15)Carlos Munoz MinuttiCecile PiotMariana Pereira Da Costa Probir ChakravartyNeil RogersHector Huerga Encabo[...] Jean LanghorneDominique Bonnet Marc Dalod Elena TomaselloCaetano Reis e Sousa Nature Immunology Published 1 March 2024 Crick labs/ facilitiesCaetano Reis e SousaJean LanghorneGeorge KassiotisDominique BonnetBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells Authors (15)Conor Henry Carlos A CastellanosMichael BuckEvangelos GiampazoliasBruno FredericoAna Matos Cardoso Da Silva[...]Peter FaullBram Snijders Bhopal Mohapatra Hamid BandCaetano Reis e Sousa Cell Reports Published 26 December 2023 Crick labs/ facilitiesCaetano Reis e SousaProteomicsFlow CytometryBiological Research FacilityFull details
Endothelial AHR activity prevents lung barrier disruption in viral infection Authors (13)Jack MajorStefania CrottaKatja Finsterbusch Probir ChakravartyKathleen ShahBruno Frederico[...] Lucy Meader Alejandro Suarez-BonnetSimon PriestnallBrigitta StockingerAndreas Wack Nature Published 28 September 2023 Crick labs/ facilitiesAndreas WackGitta StockingerCaetano Reis e SousaLight MicroscopyExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Interplay between CXCR4 and CCR2 regulates bone marrow exit of dendritic cell progenitors Authors (11)Mariana Pereira Da CostaCarlos Munoz MinuttiCecile PiotEvangelos GiampazoliasAna Matos Cardoso Da SilvaMaria Del Mar Cabeza CabrerizoNeil RogersMarta de Lebrusant FernandezChrysante IliakisAndreas WackCaetano Reis e Sousa Cell Reports Published 29 August 2023 Crick labs/ facilitiesAndreas WackCaetano Reis e SousaPatricia BarralFlow CytometryBiological Research FacilityFull details
Loss of TET2 in human hematopoietic stem cells alters the development and function of neutrophils Authors (22)Hector Huerga EncaboIker Valle AramburuManuel Garcia AlbornozMarion Piganeau Henry Wood Anna Song[...] Daniel H Wiseman Kiran Batta Rajeev GuptaVenizelos PapayannopoulosDominique Bonnet Cell Stem Cell Published 1 June 2023 Crick labs/ facilitiesCaetano Reis e SousaVenizelos PapayannopoulosDominique BonnetLight MicroscopyElectron MicroscopyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
The dietary sweetener sucralose is a negative modulator of T cell-mediated responses Authors (16)Fabio ZaniJulianna Blagih Tim GruberMichael Buck Nicholas JonesMarc Hennequart[...]Eric Cheung Ian S GilmoreAlex Gould Cristina Garcia-CaceresKaren Vousden Nature Published 23 March 2023 Crick labs/ facilitiesKaren VousdenCaetano Reis e SousaAlex GouldMetabolomicsBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
In vivo analysis of dendritic cell clonality Authors (1)Maria Del Mar Cabeza Cabrerizo Methods in Molecular Biology Published 12 March 2023 Crick labs/ facilitiesCaetano Reis e SousaLight MicroscopyFlow CytometryBiological Research FacilityFull details
DNGR-1-mediated cross-presentation of dead cell-associated antigens Authors (3)Conor Henry Carlos A CastellanosCaetano Reis e Sousa Seminars in Immunology Published 7 February 2023 Crick labsCaetano Reis e SousaFull details
Loss of secreted gelsolin enhances response to anticancer therapies Authors (8)Jonathan LimEvangelos GiampazoliasOliver SchulzNeil Rogers Anna WilkinsErik Sahai Jessica StridCaetano Reis e Sousa Journal for ImmunoTherapy of Cancer Published 26 September 2022 Crick labs/ facilitiesErik SahaiCaetano Reis e SousaBiological Research FacilityFull details
DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential Authors (17)Bruno Frederico Isaura Martins Diana ChapelaFrancesca Gasparrini Probir ChakravartyTobias Ackels[...]James BriscoeFrancois GuillemotAndreas Schaefer Leonor SaúdeCaetano Reis e Sousa Developmental Cell Published 22 August 2022 Crick labs/ facilitiesAndreas SchaeferCaetano Reis e SousaFrancois GuillemotJames BriscoeLight MicroscopyExperimental HistopathologyElectron MicroscopyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityFull details
RNA sensing via the RIG-I-like receptor LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency Authors (8) Jorn E Stok Timo Oosenbrug Laurens R ter Haar Dennis Gravekamp Christian P Bromley Santiago ZelenayCaetano Reis e Sousa Annemarthe G van der Veen The EMBO Journal Published 15 March 2022 Crick labsCaetano Reis e SousaFull details
The impact of COVID-19 on oncology professionals-one year on: lessons learned from the ESMO Resilience Task Force survey series Authors (17) KHJ Lim K Murali E Thorne K Punie K Kamposioras C Oing[...] CB Westphalen G Morgan JBAG Haanen C Hardy S Banerjee ESMO Open Published 1 February 2022 Crick labsCaetano Reis e SousaFull details
Epithelial colonization by gut dendritic cells promotes their functional diversification Authors (23) Claudia A Rivera Violaine Randrian Wilfrid Richer Yohan Gerber-Ferder Maria-Graciela Delgado Aleksandra S Chikina[...] Hélène D Moreau Julie Helft Danijela Matic Vignjevic Eduardo J Villablanca Ana-Maria Lennon-Duménil Immunity Published 11 January 2022 Crick labsCaetano Reis e SousaFull details
Maintenance and loss of endocytic organelle integrity: mechanisms and implications for antigen cross-presentation Authors (4)Eleanor ChildsConor Henry Johnathan CantonCaetano Reis e Sousa Open Biol Published 10 November 2021 Crick labsCaetano Reis e SousaFull details
Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity Authors (18)Maria Del Mar Cabeza CabrerizoCarlos Munoz Minutti Mariana Pereira da CostaAna Matos Cardoso Da SilvaRob JenkinsJustina Kulikauskaite[...] Judith E Allen Manolis PasparakisAndreas WackErik SahaiCaetano Reis e Sousa Science Immunology Published 5 November 2021 Crick labs/ facilitiesAndreas WackErik SahaiCaetano Reis e SousaNicola LewisDominique BonnetWorldwide Influenza CentreFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsFull details
From mRNA sensing to vaccines Authors (9) Anthony S Fauci Miriam Merad Soumya Swaminathan Sun Hur Eric Topol Kate FitzgeraldCaetano Reis e Sousa Kizzmekia S Corbett Stefan Bauer Immunity Published 14 December 2021 Crick labsCaetano Reis e SousaFull details
An isoform of Dicer protects mammalian stem cells against multiple RNA viruses Authors (10)Enzo PoirierMichael Buck Probir ChakravartyJoana Do Vale Viegas Silva CarvalhoBruno FredericoAna Matos Cardoso Da SilvaLyn HealyRachel UlfertsRupert BealeCaetano Reis e Sousa Science Published 9 July 2021 Crick labs/ facilitiesCaetano Reis e SousaRupert BealeHuman Embryonic Stem CellExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryAdvanced SequencingFull details
Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity Authors (17)Evangelos GiampazoliasOliver SchulzJonathan LimNeil Rogers Probir Chakravarty Naren Srinivasan[...] Stefano Sammicheli Natalia MoncautSunita Varsani-BrownIan RosewellCaetano Reis e Sousa Cell Published 22 July 2021 Crick labs/ facilitiesCaetano Reis e SousaGenetic Modification ServiceBiological Research FacilityBioinformatics and BiostatisticsFlow CytometryFull details
Dendritic cells revisited Authors (5)Maria Del Mar Cabeza CabrerizoAna Matos Cardoso Da SilvaCarlos Munoz MinuttiMariana Pereira Da CostaCaetano Reis e Sousa Annual Review of Immunology Published 1 April 2021 Crick labsCaetano Reis e SousaFull details