Folkert van Werven: Biography

Folkert van Werven obtained a BSc from University College Utrecht in 2001, and an MSc in applied bioscience from Hokkaido University in 2003. In 2009 he obtained a PhD from the University of Utrecht. During his PhD he developed and used genome-wide approaches to understand how basal transcription factors are dynamically recruited to gene promoters.

After completing his PhD he joined the laboratory of Angelika Amon at the Massachusetts Institute of Technology in the USA. There he studied how entry into yeast gametogenesis is regulated. The work led to the discovery that in cells with a single mating type transcription of two long noncoding RNAs represses two master regulatory genes of gametogenesis. The mechanism involved includes transcription coupled recruitment and repression by highly conserved chromatin regulators.

Folkert's work at the Francis Crick Institute (previously at the Cancer Research UK London Research Institute) currently focuses on two main questions: (1) How does transcription of long noncoding RNAs regulate gene expression and cell fate? (2) How are multiple signals integrated to control cell fate decision making?

Folkert van Werven
+44 (0)20 379 62064

  • Qualifications and history
  • 2009 PhD, University Medical Center Utrecht/University of Utrecht, Netherlands
  • 2009 - 2013 Postdoctoral Associate/Fellow, Massachusetts Institute of Technology, Cambridge, USA 
  • 2013 Established lab at the London Research Institute, Cancer Research UK
  • 2015 Group Leader, the Francis Crick Institute, London, UK