Michael Way: Publications

  • Burbage, M; Gasparrini, F; Aggarwal, S; Gaya, M; Arnold, J; Nair, U; Way, M; Bruckbauer, A and Batista, FD (2018)
    Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity.
    eLife 7, e26556 PubMed abstract
  • Way, M (2018)
    2017 Winner: Seth Zimmerman.
    Journal of Cell Science 131, 1 PubMed abstract
  • Ahmad, SA and Way, M (2017)
    New Editor on Journal of Cell Science.
    Journal of Cell Science 130, 303 PubMed abstract
  • Durkin, CH; Leite, F; Cordeiro, JV; Handa, Y; Arakawa, Y; Valderrama, F and Way, M (2017)
    RhoD inhibits RhoC-ROCK-dependent cell contraction via PAK6.
    Developmental Cell 41, 315-329.e317 PubMed abstract
  • Peddie, CJ; Domart, M-C; Snetkov, X; O'Toole, P; Larijani, B; Way, M; Cox, S and Collinson, LM (2017)
    Correlative super-resolution fluorescence and electron microscopy using conventional fluorescent proteins in vacuo.
    Journal of Structural Biology 199, 120-131 PubMed abstract
  • Postigo, A; Ramsden, AE; Howell, M and Way, M (2017)
    Cytoplasmic ATR activation promotes vaccinia virus genome replication.
    Cell Reports 19, 1022-1032 PubMed abstract
  • Roman, W; Martins, JP; Carvalho, FA; Voituriez, R; Abella, JVG; Santos, NC; Cadot, B; Way, M and Gomes, ER (2017)
    Myofibril contraction and crosslinking drive nuclear movement to the periphery of skeletal muscle.
    Nature Cell Biology 19, 1189-1201 PubMed abstract
  • Sansregret, L; Patterson, JO; Dewhurst, S; López-García, C; Koch, A; McGranahan, N; Chao, WCH; Barry, DJ; Rowan, A; Instrell, R; Horswell, S; Way, M; Howell, M; Singleton, MR; Medema, RH; Nurse, P; Petronczki, M and Swanton, C (2017)
    APC/C dysfunction limits excessive cancer chromosomal instability.
    Cancer Discovery 7, 218-233 PubMed abstract
  • Way, M (2017)
    2016 Winner: Viswanadh Madugula.
    Journal of Cell Science 130, 1197 PubMed abstract
  • Way, M (2017)
    Publisher's Note - Relating to the retraction of: Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitration. Azza B. El-Remessy, Manuela Bartoli, Danial H. Platt, David Fulton, Ruth B. Caldwell. J. Cell Sci. doi:10.1242/jcs.195966.
    Journal of Cell Science 130, 1856 PubMed abstract
  • Way, M (2017)
    "What I cannot create, I do not understand".
    Journal of Cell Science 130, 2941-2942 PubMed abstract
  • Abella, JVG; Galloni, C; Pernier, J; Barry, DJ; Kjær, S; Carlier, M-F and Way, M (2016)
    Isoform diversity in the Arp2/3 complex determines actin filament dynamics.
    Nature Cell Biology 18, 76-86 PubMed abstract
  • Abella, JVG and Way, M (2016)
    Actin'g against the ball and chain.
    Developmental Cell 37, 11-12 PubMed abstract
  • Ahmad, SA and Way, M (2016)
    New Editor on Journal of Cell Science.
    Journal of Cell Science 129, 2287 PubMed abstract
  • Fernández-Escobar, M; Nájera, JL; Baldanta, S; Rodriguez, D; Way, M; Esteban, M and Guerra, S (2016)
    Suppression of NYVAC infection in HeLa cells requires RNase L but is independent of Protein Kinase R activity.
    Journal of Virology 90, 2135-2141 PubMed abstract
  • Sirianni, A; Krokowski, S; Lobato-Márquez, D; Buranyi, S; Pfanzelter, J; Galea, D; Willis, A; Culley, S; Henriques, R; Larrouy-Maumus, G; Hollinshead, M; Sancho-Shimizu, V; Way, M and Mostowy, S (2016)
    Mitochondria mediate septin cage assembly to promote autophagy of Shigella.
    EMBO Reports 17, 1029-1043 PubMed abstract
  • Snetkov, X; Weisswange, I; Pfanzelter, J; Humphries, AC and Way, M (2016)
    NPF motifs in the vaccinia virus protein A36 recruit intersectin-1 to promote Cdc42:N-WASP-mediated viral release from infected cells.
    Nature Microbiology 1, 16141 PubMed abstract
  • Way, M (2016)
    2015 Winner: Monika Zwerger.
    Journal of Cell Science 129, 1083-1084 PubMed abstract
  • Way, M (2016)
    The good, the bad and the median.
    Journal of Cell Science 129, 3205 PubMed abstract
  • Way, M (2016)
    Journal of Cell Science is going green.
    Journal of Cell Science 129, 3519 PubMed abstract
  • Ahmad, SA and Way, M (2015)
    Plus ça change.
    Journal of Cell Science 128, 4247-4248 PubMed abstract
  • Barry, DJ; Durkin, CH; Abella, JV and Way, M (2015)
    Open source software for quantification of cell migration, protrusions, and fluorescence intensities.
    Journal of Cell Biology 209, 163-180 PubMed abstract
  • Brama, E; Peddie, CJ; Jones, ML; Domart, M-C; Snetkov, X; Way, M; Larijani, B and Collinson, LM (2015)
    Standard fluorescent proteins as dual-modality probes for correlative experiments in an integrated light and electron microscope.
    Journal of Chemical Biology 8, 179-188
  • Ferrari, N; Riggio, AI; Mason, S; McDonald, L; King, A; Higgins, T; Rosewell, I; Neil, JC; Smalley, MJ; Sansom, OJ; Morris, J; Cameron, ER and Blyth, K (2015)
    Runx2 contributes to the regenerative potential of the mammary epithelium.
    Scientific Reports 5, 15658 PubMed abstract
  • Gill, MB; Turner, R; Stevenson, PG and Way, M (2015)
    KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction.
    EMBO Journal 34, 448-465 PubMed abstract
  • Hanč, P; Fujii, T; Iborra, S; Yamada, Y; Huotari, J; Schulz, O; Ahrens, S; Kjær, S; Way, M; Sancho, D; Namba, K and Reis e Sousa, C (2015)
    Structure of the complex of F-actin and DNGR-1, a C-type lectin receptor involved in dendritic cell cross-presentation of dead cell-associated antigens.
    Immunity 42, 839-849 PubMed abstract
  • Keppler, SJ; Gasparrini, F; Burbage, M; Aggarwal, S; Frederico, B; Geha, RS; Way, M; Bruckbauer, A and Batista, FD (2015)
    Wiskott-Aldrich syndrome interacting protein deficiency uncovers the role of the co-receptor CD19 as a generic hub for PI3 kinase signaling in B cells.
    Immunity 43, 660-673 PubMed abstract
  • Leite, F and Way, M (2015)
    The role of signalling and the cytoskeleton during Vaccinia Virus egress.
    Virus Research 209, 87-99 PubMed abstract
  • Way, M (2015)
    2014 winners: Anne-Lise Gaffuri and Elizabeth Crowell.
    Journal of Cell Science 128, 1255-1256 PubMed abstract
  • Way, M (2015)
    Andrew Ewald takes the helm of first JCS Guest Editorship.
    Journal of Cell Science 128, 2743 PubMed abstract
  • Way, M and Ahmad, SA (2015)
    JCS Editor changes.
    Journal of Cell Science 128, 831 PubMed abstract
  • Chen, XJ; Squarr, AJ; Stephan, R; Chen, B; Higgins, TE; Barry, DJ; Martin, MC; Rosen, MK; Bogdan, S and Way, M (2014)
    Ena/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton.
    Developmental Cell 30, 569-584 PubMed abstract
  • Humphries, AC; Donnelly, SK and Way, M (2014)
    Cdc42 and the Rho GEF intersectin-1 collaborate with Nck to promote N-WASP-dependent actin polymerisation.
    Journal of Cell Science 127, 673-685 PubMed abstract
  • Way, M (2014)
    JCS Prize. 2013 winner: Liam Cheeseman.
    Journal of Cell Science 127, 2121 PubMed abstract
  • Young, JC; Clements, A; Lang, AE; Garnett, JA; Munera, D; Arbeloa, A; Pearson, J; Hartland, EL; Matthews, SJ; Mousnier, A; Barry, DJ; Way, M; Schlosser, A; Aktories, K and Frankel, G (2014)
    The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation.
    Nature Communications 5, 5887 PubMed abstract
  • Donnelly, SK; Weisswange, I; Zettl, M and Way, M (2013)
    WIP provides an essential link between Nck and N-WASP during Arp2/3-dependent actin polymerization.
    Current Biology 23, 999-1006 PubMed abstract
  • Gerlic, M; Faustin, B; Postigo, A; Yu, EC-W; Proell, M; Gombosuren, N; Krajewska, M; Flynn, R; Croft, M; Way, M; Satterthwait, A; Liddington, RC; Salek-Ardakani, S; Matsuzawa, S-i and Reed, JC (2013)
    Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation.
    Proceedings of the National Academy of Sciences of the United States of America 110, 7808-7813 PubMed abstract
  • Handa, Y; Durkin, CH; Dodding, MP and Way, M (2013)
    Vaccinia virus F11 promotes viral spread by acting as a PDZ-containing scaffolding protein to bind Myosin-9A and inhibit RhoA signaling.
    Cell Host & Microbe 14, 51-62 PubMed abstract
  • Humphries, AC and Way, M (2013)
    The non-canonical roles of clathrin and actin in pathogen internalization, egress and spread.
    Nature Reviews Microbiology 11, 551-560 PubMed abstract
  • Stricker, SH; Feber, A; Engström, PG; Carén, H; Kurian, KM; Takashima, Y; Watts, C; Way, M; Dirks, P; Bertone, P; Smith, A; Beck, S and Pollard, SM (2013)
    Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner.
    Genes & Development 27, 654-669 PubMed abstract
  • Way, M (2013)
    JCS Prize. 2012 winners: Vincent Pasque and Aliaksandra Radzisheuskaya.
    Journal of Cell Science 126, 1287-1288
  • Way, M and Ahmad, SA (2013)
    New JCS editor.
    Journal of Cell Science 126, 4807
  • Way, M and Ahmad, SA (2013)
    The San Francisco declaration on research assessment.
    Journal of Cell Science 126, 1903-1904 PubMed abstract
  • Welch, MD and Way, M (2013)
    Arp2/3-mediated actin-based motility: a tail of pathogen abuse.
    Cell Host & Microbe 14, 242-255 PubMed abstract
  • Ahrens, S; Zelenay, S; Sancho, D; Hanč, P; Kjær, S; Feest, C; Fletcher, G; Durkin, C; Postigo, A; Skehel, M; Batista, F; Thompson, B; Way, M; Reis e Sousa, C and Schulz, O (2012)
    F-actin is an evolutionarily conserved damage-associated molecular pattern recognized by DNGR-1, a receptor for dead cells.
    Immunity 36, 635-645 PubMed abstract
  • Dart, AE; Donnelly, SK; Holden, DW; Way, M and Caron, E (2012)
    Nck and Cdc42 co-operate to recruit N-WASP to promote FcγR-mediated phagocytosis.
    Journal of Cell Science 125, 2825-2830 PubMed abstract
  • Humphries, AC; Dodding, MP; Barry, DJ; Collinson, LM; Durkin, CH and Way, M (2012)
    Clathrin potentiates vaccinia-induced actin polymerization to facilitate viral spread.
    Cell Host & Microbe 12, 346-359 PubMed abstract
  • Lynn, H; Horsington, J; Ter, LK; Han, S; Chew, YL; Diefenbach, RJ; Way, M; Chaudhri, G; Karupiah, G and Newsome, TP (2012)
    Loss of cytoskeletal transport during egress critically attenuates ectromelia virus infection in vivo.
    Journal of Virology 86, 7427-7443 PubMed abstract
  • Postigo, A and Way, M (2012)
    The vaccinia virus-encoded Bcl-2 homologues do not act as direct Bax inhibitors.
    Journal of Virology 86, 203-213 PubMed abstract
  • Way, M (2012)
    A fresh start--but business as usual.
    Journal of Cell Science 125, 1-2 PubMed abstract
  • Way, M (2012)
    JCS Prize. 2011 winner: Carla Lopes.
    Journal of Cell Science 125, 791
  • Wiezlak, M; Diring, J; Abella, J; Mouilleron, S; Way, M; McDonald, NQ and Treisman, R (2012)
    G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly.
    Journal of Cell Science 125, 5860-5872 PubMed abstract
  • Alberts, A and Way, M (2011)
    Actin motility: formin a SCAry tail.
    Current Biology 21, R27-R30 PubMed abstract
  • Boëda, B; Knowles, PP; Briggs, DC; Murray-Rust, J; Soriano, E; Garvalov, BK; McDonald, NQ and Way, M (2011)
    Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A.
    Journal of Biological Chemistry 286, 11543-11554 PubMed abstract
  • Dodding, MP; Mitter, R; Humphries, AC and Way, M (2011)
    A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome.
    EMBO Journal 30, 4523-4538 PubMed abstract
  • Dodding, MP and Way, M (2011)
    Coupling viruses to dynein and kinesin-1.
    EMBO Journal 30, 3527-3539 PubMed abstract
  • Strunze, S; Engelke, MF; Wang, IH; Puntener, D; Boucke, K; Schleich, S; Way, M; Schoenenberger, P; Burckhardt, CJ and Greber, UF (2011)
    Kinesin-1-mediated capsid disassembly and disruption of the nuclear pore complex promote virus infection.
    Cell Host & Microbe 10, 210-223 PubMed abstract

[Page last updated 1 Jun 2018]

Michael Way

+44 (0)20 379 62068

  • Qualifications and History
  • 1988 PhD in Structural Studies, Cambridge University, UK
  • 1989 Postdoctoral Fellow, LMB, Cambridge, UK
  • 1992 Postdoctoral Fellow, Whitehead Institute, Massachusetts, USA
  • 1995 Group Leader, Cell Biology Programme, EMBL, Germany
  • 2001 Established lab at the Imperial Cancer Research Fund, UK (in 2002 the Imperial Cancer Research Fund became Cancer Research UK)
  • 2015 Group Leader, the Francis Crick Institute, London, UK