Lipid droplets (shown in green) can build up in cells from malnourished humans and other animals

Health and ageing

How do organisms maintain health and balance throughout life and as they age?

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Our bodies are exceptionally good at staying constant in a changing environment. But as we age, the processes that keep things in balance start to break down. As a result, damage starts to accumulate, and can, over time, contribute to disease. 

At the Crick, we are researching the molecular and cellular causes of ageing so that we can identify ways to stave off neurodegenerative diseases, cardiovascular disease, cancer and other age-related conditions. 

We’re studying how the body heals itself so that organisms can stay healthy for longer, and are coming up with innovative stem cell approaches to repair or replace damaged tissue and organs.

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