
Andreas Wack
- Lab: Immunoregulation Laboratory
- Job Title: Group Leader
- Email Address:
- Phone Number: +44 (0)20 3796 1624
Qualifications and history
- 1999 PhD, MRC-NIMR and University of Konstanz, Germany
- 1999-2009 Post doctoral fellow then group leader, Novartis Vaccines, Siena, Italy
- 2009 Group leader, Medical Research Council National Institute for Medical Research, London, UK
- 2015 Group leader, the Francis Crick Institute, London, UK
Andreas Wack was born in Frankfurt, studied biology in Konstanz and got his first degree based upon a thesis on the clonal composition of T cell populations in the elderly. He performed his PhD work at the Medical Research Council National Institute for Medical Research (now part of the Francis Crick Institute) under the supervision of Dimitris Kioussis on thymocyte lineage decisions and went on to do a postdoc and work as a staff scientist in the research institute of Novartis Vaccines, formely Chiron, in Siena, Italy.
The focus of his work there was the modulation of T and NK cell function by the hepatitis C virus, human dendritic cell subsets and their crosstalk, the mechanism of action of mucosal and parenteral vaccine adjuvants, and next generation influenza vaccines.
His current research interests at the Crick include the understanding of pathogenesis and protection in influenza infection and influenza-bacterial coinfection. He is also interested in the anti-influenza response of airway epithelia and their interplay with the immune system. To address these questions, human and murine primary airway epithelial cell cultures and immune cells are used as well as in vivo infection models.
Year published
Research topics
- Biochemistry & Proteomics (1)
- Cell Biology (5)
- Cell Cycle & Chromosomes (3)
- Chemical Biology & High Throughput (6)
- Computational & Systems Biology (8)
- Developmental Biology (3)
- Gene Expression (2)
- Genetics & Genomics (7)
- Genome Integrity & Repair (6)
- Human Biology & Physiology (20)
- Imaging (2)
- Immunology (19)
- Infectious Disease (20)
- Metabolism (3)
- Microfabrication & Bioengineering (1)
- Model Organisms (19)
- Neurosciences (2)
- Signalling & Oncogenes (4)
- Stem Cells (3)
- Structural Biology & Biophysics (4)
- Synthetic Biology (1)
- Tumour Biology (6)
Crick Pre-Crick
Journal
- Cell (1)
- Cell Reports (1)
- Current Opinion in Virology (1)
- eLife (1)
- EMBO Molecular Medicine (1)
- EMBO Reports (1)
- Human Immunology (1)
- Journal of Experimental Medicine (4)
- Journal of hepatology (1)
- Journal of Immunology (3)
- Journal of Infectious Diseases (1)
- Journal of Innate Immunity (1)
- Journal of Interferon & Cytokine Research (1)
- Nature Biotechnology (1)
- Nature Communications (4)
- Nature Genetics (1)
- Nature Immunology (4)
- Nature Reviews Immunology (1)
- PLOS Pathogens (1)
- Proceedings of the National Academy of Sciences of the United States of America (1)
- Scandinavian Journal of Immunology (1)
- Science (1)
- The Lancet (1)
- Trends in Immunology (1)
- Vaccine (1)