Annabel Borg

SENIOR LABORATORY RESEARCH SCIENTIST

Structural Biology

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Displaying 1 - 13 of 13

Last updated : 21 March 2023 02:29

O-linked sialoglycans modulate the proteolysis of SARS-CoV-2 spike and likely contribute to the mutational trajectory in variants of concern

Authors (22)

Edgar Gonzalez-Rodriguez
Mia Zol-Hanlon
Ganka Bineva-Todd
Andrea Marchesi
Mark Skehel
Keira E Mahoney
[...]
Robert Wilkinson
Emma C Wall
Ramón Hurtado-Guerrero
Stacy A Malaker
Ben Schumann

ACS Central Science

Published 16 February 2023

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Strong peak immunogenicity but rapid antibody waning following third vaccine dose in older residents of care homes

Authors (68)

G Tut
T Lancaster
M Krutikov
P Sylla
D Bone
E Spalkova
[...]
A Irwin-Singer
A Hayward
A Copas
L Shallcross
P Moss

Nature Aging

Published 1 January 2023

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A KLK6 activity-based probe reveals a role for KLK6 activity in pancreatic cancer cell invasion

Authors (11)

Leran Zhang
Scott Lovell
Elena De Vita
Pravin Kumar Ankush Jagtap
Daniel Lucy
Andrea Goya Grocin
Svend Kjaer
Annabel Borg
Janosch Hennig
Aubry K Miller
Edward W Tate

Journal of the American Chemical Society

Published 14 December 2022

Crick labs/ facilities

Structural Biology

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Evolution of the SARS-CoV-2 spike protein in the
human host

Authors (9)

Nature Communications

Published 4 March 2022

Crick labs/ facilities

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Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients

Authors (86)

The Lancet

Published 18 September 2021

Crick labs/ facilities

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The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2

Authors (9)

Proceedings of the National Academy of Sciences of USA

Published 2 March 2021

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Structure and binding properties of Pangolin-CoV spike glycoprotein inform the evolution of SARS-CoV-2

Authors (10)

Nature Communications

Published 5 February 2021

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A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing

Authors (14)

Sarah Adams
Andrew G Purkiss
Phillip P Knowles
Andrea Nans
David Briggs
Annabel Borg
[...]
Aaron J Borg
Pauline B McIntosh
Frankie Houghton
Svend Kjaer
Neil McDonald

Structure

Published 1 July 2021

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Cysteine-reactive free ISG15 generates IL-1β-producing CD8α+ dendritic cells at the site of infection

Authors (11)

Anna Napolitano
Annemarthe G van der Veen
Monique Bunyan
Annabel Borg
David Frith
Steven Howell
Svend Kjaer
Antje Beling
Bram Snijders
Klaus-Peter Knobeloch
Eva-Maria Frickel

Journal of Immunology

Published 15 July 2018

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The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells

Authors (9)

Annemarthe G van der Veen
Pierre V Maillard
Jan Marten Schmidt
Sonia Lee
Safia Deddouche-Grass
Annabel Borg
Svend Kjaer
Bram Snijders
Caetano Reis e Sousa

EMBO Journal

Published 15 February 2018

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RET functions as a dual-specificity kinase that requires allosteric inputs from juxtamembrane elements

Authors (10)

Iván Plaza-Menacho
Karin Barnouin
Rachael Barry
Annabel Borg
Mariam Orme
Rakhee Chauhan
Stephane Mouilleron
Rubén J Martínez-Torres
Pascal Meier
Neil McDonald

Cell Reports

Published 20 December 2016

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Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN

Authors (13)

Julian Stingele
Roberto Bellelli
Ferdinand Alte
Graeme Hewitt
Grzegorz Sarek
Sarah L Maslen
[...]
Svend Kjaer
John A Tainer
Mark Skehel
Michael Groll
Simon Boulton

Molecular Cell

Published 17 November 2016

Crick labs/ facilities

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About us

Annabel Borg

SENIOR LABORATORY RESEARCH SCIENTIST

Structural Biology

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Crick Pre-Crick

O-linked sialoglycans modulate the proteolysis of SARS-CoV-2 spike and likely contribute to the mutational trajectory in variants of concern

Strong peak immunogenicity but rapid antibody waning following third vaccine dose in older residents of care homes

A KLK6 activity-based probe reveals a role for KLK6 activity in pancreatic cancer cell invasion

Evolution of the SARS-CoV-2 spike protein in the
human host

Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase

The effect of the D614G substitution on the structure of the spike glycoprotein of SARS-CoV-2

Structure and binding properties of Pangolin-CoV spike glycoprotein inform the evolution of SARS-CoV-2

A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing

Cysteine-reactive free ISG15 generates IL-1β-producing CD8α+ dendritic cells at the site of infection

The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells

RET functions as a dual-specificity kinase that requires allosteric inputs from juxtamembrane elements

Mechanism and regulation of DNA-protein crosslink repair by the DNA-dependent metalloprotease SPRTN

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