Technical training Our platforms and facilities have training available for researchers outside the Crick.
We Go Way Back 16 Jul - 2 Jul Unlock the secrets hidden in our DNA and discover the extraordinary story of humanity.
Breadcrumb Research A-Z researchers Aurora Idilli Postdoctoral Fellow Boulton lab DSB Repair Metabolism Laboratory Email Address: Crick email Email Year published 2026 (4) 2025 (1) 2021 (2) Facet Year published Research topics Biochemistry & Proteomics (2) Cell Biology (4) Cell Cycle & Chromosomes (4) Genetics & Genomics (3) Genome Integrity & Repair (4) Model Organisms (2) Signalling & Oncogenes (1) Facet Research topics Crick Pre-Crick Crick publications (7) Facet Crick Pre-Crick Publication type Journal article (4) Method (1) Preprint (3) Primary research (3) Facet Publication type Journal BioRxiv (3) Nature Cell Biology (1) Nature Communications (1) Nature Structural & Molecular Biology (1) STAR Protocols (1) Facet Journal Displaying 1 - 7 of 7Last updated : 04 September 2026 03:37 MEN1 deficiency creates a selenite-dependent switch in ferroptosis Preprint Authors (8) Ronnie Ren Jie Low Venkata Nishita Mohan Parnandi Aurora Idilli Ersa Gjelaj Fernanda Teixeira Subtil Sandra Segura-Bayona James MacRae Simon Boulton bioRxiv Published 16 July 2026 Crick labs/ facilities Simon Boulton Metabolomics Genomics Cell Science Full details Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard replication and telomere integrity Authors (20) Sandra Segura-Bayona Marija Maric Tohru Takaki Zornitsa Manova Tyler Stanage Aurora Idilli [...] Harshil Patel Steven Howell Panagiotis Kotsantis Michael Howell Simon Boulton Nature Structural & Molecular Biology Published 1 July 2026 Crick labs/ facilities Simon Boulton Proteomics Light Microscopy Screening and Automated Science Bioinformatics and Biostatistics Making Lab Genomics Flow Cytometry Cell Science Full details Phenotype-first covalent fragment screening identifies a synthetic lethal TYMS inhibitor in ATRX-deficient cells Preprint Authors (18) Federica Raguseo Elliot Fellows Cesira De Chiara Benjamin Mortishire-Smith Sandra Segura-Bayona Emma Cawood [...] Mark Skehel Andrew J Powell David House Jacob T Bush Simon Boulton bioRxiv Published 11 June 2026 Crick labs/ facilities Katrin Rittinger Simon Boulton Translation team Proteomics Metabolomics Screening and Automated Science Structural Biology Cell Science Full details RPA exhaustion activates SLFN11 to eliminate cells with heightened replication stress Authors (7) Tyler Stanage Shudong Li Sandra Segura-Bayona Aurora Idilli Rhona Millar Graeme Hewitt Simon Boulton Nature Cell Biology Published 1 February 2026 Crick labs/ facilities Simon Boulton Screening and Automated Science Genomics Flow Cytometry Cell Science Full details SLFN11 restricts escape from telomere crisis to prevent alternative lengthening of telomeres Preprint Authors (25) Sandra Segura-Bayona Valerie Borel Tyler Stanage Marija Maric Melanie Walter Rafaela A Oliveira [...] Roderick J O'Sullivan Aatur D Singhi Thijn R Brummelkamp Anthony J Cesare Simon Boulton bioRxiv Published 10 September 2025 Crick labs/ facilities Simon Boulton Genomics Experimental Histopathology Bioinformatics and Biostatistics Light Microscopy Screening and Automated Science Flow Cytometry Cell Science Full details A C-circle assay for detection of alternative lengthening of telomere activity in FFPE tissue Authors (4) Aurora Idilli Sandra Segura-Bayona Timothy P Lippert Simon Boulton STAR Protocols Published 18 June 2021 Crick labs/ facilities Simon Boulton Experimental Histopathology Full details Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres Authors (10) Timothy P Lippert Paulina Marzec Aurora Idilli Grzegorz Sarek Aleksandra Vancevska Mark Bower Paul J Farrell Päivi M Ojala Niklas Feldhahn Simon Boulton Nature Communications Published 21 January 2021 Crick labs/ facilities Simon Boulton Experimental Histopathology Full details
MEN1 deficiency creates a selenite-dependent switch in ferroptosis Preprint Authors (8) Ronnie Ren Jie Low Venkata Nishita Mohan Parnandi Aurora Idilli Ersa Gjelaj Fernanda Teixeira Subtil Sandra Segura-Bayona James MacRae Simon Boulton bioRxiv Published 16 July 2026 Crick labs/ facilities Simon Boulton Metabolomics Genomics Cell Science Full details
Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard replication and telomere integrity Authors (20) Sandra Segura-Bayona Marija Maric Tohru Takaki Zornitsa Manova Tyler Stanage Aurora Idilli [...] Harshil Patel Steven Howell Panagiotis Kotsantis Michael Howell Simon Boulton Nature Structural & Molecular Biology Published 1 July 2026 Crick labs/ facilities Simon Boulton Proteomics Light Microscopy Screening and Automated Science Bioinformatics and Biostatistics Making Lab Genomics Flow Cytometry Cell Science Full details
Phenotype-first covalent fragment screening identifies a synthetic lethal TYMS inhibitor in ATRX-deficient cells Preprint Authors (18) Federica Raguseo Elliot Fellows Cesira De Chiara Benjamin Mortishire-Smith Sandra Segura-Bayona Emma Cawood [...] Mark Skehel Andrew J Powell David House Jacob T Bush Simon Boulton bioRxiv Published 11 June 2026 Crick labs/ facilities Katrin Rittinger Simon Boulton Translation team Proteomics Metabolomics Screening and Automated Science Structural Biology Cell Science Full details
RPA exhaustion activates SLFN11 to eliminate cells with heightened replication stress Authors (7) Tyler Stanage Shudong Li Sandra Segura-Bayona Aurora Idilli Rhona Millar Graeme Hewitt Simon Boulton Nature Cell Biology Published 1 February 2026 Crick labs/ facilities Simon Boulton Screening and Automated Science Genomics Flow Cytometry Cell Science Full details
SLFN11 restricts escape from telomere crisis to prevent alternative lengthening of telomeres Preprint Authors (25) Sandra Segura-Bayona Valerie Borel Tyler Stanage Marija Maric Melanie Walter Rafaela A Oliveira [...] Roderick J O'Sullivan Aatur D Singhi Thijn R Brummelkamp Anthony J Cesare Simon Boulton bioRxiv Published 10 September 2025 Crick labs/ facilities Simon Boulton Genomics Experimental Histopathology Bioinformatics and Biostatistics Light Microscopy Screening and Automated Science Flow Cytometry Cell Science Full details
A C-circle assay for detection of alternative lengthening of telomere activity in FFPE tissue Authors (4) Aurora Idilli Sandra Segura-Bayona Timothy P Lippert Simon Boulton STAR Protocols Published 18 June 2021 Crick labs/ facilities Simon Boulton Experimental Histopathology Full details
Oncogenic herpesvirus KSHV triggers hallmarks of alternative lengthening of telomeres Authors (10) Timothy P Lippert Paulina Marzec Aurora Idilli Grzegorz Sarek Aleksandra Vancevska Mark Bower Paul J Farrell Päivi M Ojala Niklas Feldhahn Simon Boulton Nature Communications Published 21 January 2021 Crick labs/ facilities Simon Boulton Experimental Histopathology Full details
