Barbara Clough

Lab: Host-Toxoplasma Interaction Laboratory
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Job Title: Principal Laboratory Research Scientist

Displaying 1 - 10 of 10

Last updated : 24 September 2020 03:29

Mimicry embedding facilitates advanced neural network training for image-based pathogen detection

Authors (8)

Artur Yakimovich
Moona Huttunen
Jerzy Samolej
Barbara Clough
Nagisa Yoshida
Serge Mostowy
Eva Frickel
Jason Mercer

mSphere

Published 9 September 2020

Crick labs

Eva Frickel

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Human GBP1 differentially targets Salmonella and Toxoplasma to license recognition of microbial ligands and caspase-mediated death

Authors (10)

Daniel Fisch
Barbara Clough
Marie-Charlotte Domart
Vesela Encheva
Hironori Bando
Bram Snijders
Lucy Collinson
Masahiro Yamamoto
Avinash R Shenoy
Eva Frickel

Cell Reports

Published 11 August 2020

Crick labs/ facilities

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Human immunity to Toxoplasma gondii

Authors (3)

PLOS Pathogens

Published 12 December 2019

Crick labs

Eva Frickel

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Image-based quantitation of host cell-Toxoplasma gondii interplay using HRMAn: A host response to microbe analysis pipeline

Authors (5)

Daniel Fisch
Artur Yakimovich
Barbara Clough
Jason Mercer
Eva Frickel

Methods in Molecular Biology

Published 1 January 2020

Crick labs

Eva Frickel

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C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo

Authors (8)

Barbara Clough
Ryan Finethy
Rabia T Khan
Daniel Fisch
Sarah Jordan
Harshil Patel
Jörn Coers
Eva Frickel

Wellcome Open Research

Published 20 August 2019

Crick labs/ facilities

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Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis

Authors (7)

Daniel Fisch
Hironori Bando
Barbara Clough
Veit Hornung
Masahiro Yamamoto
Avinash R Shenoy
Eva Frickel

EMBO Journal

Published 31 May 2019

Crick labs/ facilities

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Defining host-pathogen interactions employing an artificial intelligence workflow

Authors (8)

Daniel Fisch
Artur Yakimovich
Barbara Clough
Joseph Wright
Monique Bunyan
Michael Howell
Jason Mercer
Eva Frickel

eLife

Published 12 February 2019

Crick labs/ facilities

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TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles

Authors (6)

Clémence Foltz
Anna Napolitano
Rabia Khan
Barbara Clough
Elizabeth M Hirst
Eva Frickel

Scientific Reports

Published 12 July 2017

Crick labs/ facilities

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K63-linked ubiquitination targets Toxoplasma gondii for endo-lysosomal destruction in IFNγ-stimulated human cells

Authors (7)

Barbara Clough
Joseph Wright
Pedro M Pereira
Elizabeth M Hirst
Ashleigh C Johnston
Ricardo Henriques
Eva Frickel

PLOS Pathogens

Published 22 November 2016

Crick labs/ facilities

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Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii

Authors (7)

Ashleigh C Johnston
Anthony Piro
Barbara Clough
Malvin Siew
Sebastian Virreira Winter
Jörn Coers
Eva Frickel

Cellular Microbiology

Published 1 August 2016

Crick labs/ facilities

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Barbara Clough

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Mimicry embedding facilitates advanced neural network training for image-based pathogen detection

Human GBP1 differentially targets Salmonella and Toxoplasma to license recognition of microbial ligands and caspase-mediated death

Human immunity to Toxoplasma gondii

Image-based quantitation of host cell-Toxoplasma gondii interplay using HRMAn: A host response to microbe analysis pipeline

C57BL/6 and 129 inbred mouse strains differ in Gbp2 and Gbp2b expression in response to inflammatory stimuli in vivo

Human GBP1 is a microbe-specific gatekeeper of macrophage apoptosis and pyroptosis

Defining host-pathogen interactions employing an artificial intelligence workflow

TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles

K63-linked ubiquitination targets Toxoplasma gondii for endo-lysosomal destruction in IFNγ-stimulated human cells

Human GBP1 does not localize to pathogen vacuoles but restricts Toxoplasma gondii

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