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Breadcrumb Research A Z researchers Ben Davies HEAD OF GEMS Biological Research Facility: Genetic Modification ServiceScience Technology Platform Email Address: Email Year published2023 (3)2022 (1)2021 (1)2019 (1)2013 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (2)Cell Biology (2)Genetics & Genomics (3)Imaging (3)Metabolism (2)Model Organisms (3)Signalling & Oncogenes (2) Facet Research topicsPublication typeJournal article (7)Method (2)Primary research (5) Facet Publication typeJournalCell Reports (1)Circulation Research (1)Frontiers in Cell and Developmental Biology (1)Frontiers in Immunology (1)Genome Research (1)Journal of Clinical Investigation (1)Methods in Molecular Biology (1) Facet JournalCrick Pre-CrickCrick publications (5)Pre-Crick publications (2) Facet Crick Pre-Crick Displaying 1 - 7 of 7Last updated : 01 December 2023 03:48 Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice Authors (8)Ben Davies Gang Zhang Daniela Moralli Samy Alghadban Daniel Biggs Chris Preece Peter Donnelly Anjali Gupta Hinch Genome Research Published 17 November 2023 Crick labs/ facilitiesGenetic Modification ServiceBiological Research FacilityFull details A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility Authors (13) Katrin Meindl Naomi Issler Sara Afonso Alberto Cebrian-Serrano Karin Müller Christina Sterner[...] Ralph Witzgall Enriko KlootwijkBen Davies Robert Kleta Richard Warth Frontiers in Cell and Developmental Biology Published 12 October 2023 Crick labs/ facilitiesGenetic Modification ServiceBiological Research FacilityFull details Targeted integration of transgenes at the mouse Gt(ROSA)26Sor locus Authors (3) Daniel Biggs Chiann-mun ChenBen Davies Methods in Molecular Biology Published 31 March 2023 Crick labs/ facilitiesGenetic Modification ServiceBiological Research FacilityFull details A human CD68 promoter-driven inducible cre-recombinase mouse line allows specific targeting of tissue resident macrophages Authors (5) Agata N RumianekBen Davies Keith M Channon David R Greaves Gareth SD Purvis Frontiers in Immunology Published 6 July 2022 Crick labs/ facilitiesGenetic Modification ServiceFull details Precisely tuned inhibition of HIF prolyl hydroxylases is key for cardioprotection after ischemia Authors (11) Aline Jatho Anke Zieseniss Katja Brechtel-Curth Atsushi Yamamoto Mathew L Coleman Ana M Vergel Leon Daniel BiggsBen Davies Chris W PughPeter Ratcliffe Dörthe M Katschinski Circulation Research Published 16 April 2021 Crick labsPeter RatcliffeFull details Systemic silencing of Phd2 causes reversible immune regulatory dysfunction Authors (25) Atsushi Yamamoto Joanna Hester Philip S Macklin Kento Kawai Masateru Uchiyama Daniel Biggs[...] Cheryl L Scudamore Elizabeth Soilleux Fadi IssaPeter Ratcliffe Chris W Pugh Journal of Clinical Investigation Published 3 September 2019 Crick labsPeter RatcliffeFull details A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia Authors (23) Julie Adam Ming Yang Christina Bauerschmidt Mitsuhiro Kitagawa Linda O'Flaherty Pratheesh Maheswaran[...]Peter Ratcliffe Mona El-Bahrawy Houman Ashrafian Tomoyoshi Soga Patrick J Pollard Cell Reports Published 30 May 2013 Crick labsPeter RatcliffeFull details
Characterization of meiotic recombination intermediates through gene knockouts in founder hybrid mice Authors (8)Ben Davies Gang Zhang Daniela Moralli Samy Alghadban Daniel Biggs Chris Preece Peter Donnelly Anjali Gupta Hinch Genome Research Published 17 November 2023 Crick labs/ facilitiesGenetic Modification ServiceBiological Research FacilityFull details
A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility Authors (13) Katrin Meindl Naomi Issler Sara Afonso Alberto Cebrian-Serrano Karin Müller Christina Sterner[...] Ralph Witzgall Enriko KlootwijkBen Davies Robert Kleta Richard Warth Frontiers in Cell and Developmental Biology Published 12 October 2023 Crick labs/ facilitiesGenetic Modification ServiceBiological Research FacilityFull details
Targeted integration of transgenes at the mouse Gt(ROSA)26Sor locus Authors (3) Daniel Biggs Chiann-mun ChenBen Davies Methods in Molecular Biology Published 31 March 2023 Crick labs/ facilitiesGenetic Modification ServiceBiological Research FacilityFull details
A human CD68 promoter-driven inducible cre-recombinase mouse line allows specific targeting of tissue resident macrophages Authors (5) Agata N RumianekBen Davies Keith M Channon David R Greaves Gareth SD Purvis Frontiers in Immunology Published 6 July 2022 Crick labs/ facilitiesGenetic Modification ServiceFull details
Precisely tuned inhibition of HIF prolyl hydroxylases is key for cardioprotection after ischemia Authors (11) Aline Jatho Anke Zieseniss Katja Brechtel-Curth Atsushi Yamamoto Mathew L Coleman Ana M Vergel Leon Daniel BiggsBen Davies Chris W PughPeter Ratcliffe Dörthe M Katschinski Circulation Research Published 16 April 2021 Crick labsPeter RatcliffeFull details
Systemic silencing of Phd2 causes reversible immune regulatory dysfunction Authors (25) Atsushi Yamamoto Joanna Hester Philip S Macklin Kento Kawai Masateru Uchiyama Daniel Biggs[...] Cheryl L Scudamore Elizabeth Soilleux Fadi IssaPeter Ratcliffe Chris W Pugh Journal of Clinical Investigation Published 3 September 2019 Crick labsPeter RatcliffeFull details
A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia Authors (23) Julie Adam Ming Yang Christina Bauerschmidt Mitsuhiro Kitagawa Linda O'Flaherty Pratheesh Maheswaran[...]Peter Ratcliffe Mona El-Bahrawy Houman Ashrafian Tomoyoshi Soga Patrick J Pollard Cell Reports Published 30 May 2013 Crick labsPeter RatcliffeFull details
