Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
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Breadcrumb Research A Z researchers Ben Davies HEAD OF GEMS Biological Research Facility: Genetic Modification ServiceScience Technology Platform Email Address: Email Year published2022 (1)2021 (1)2019 (1)2013 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (2)Cell Biology (2)Metabolism (2)Signalling & Oncogenes (2) Facet Research topicsPublication typeJournal article (4)Primary research (4) Facet Publication typeJournalCell Reports (1)Circulation Research (1)Frontiers in Immunology (1)Journal of Clinical Investigation (1) Facet JournalCrick Pre-CrickCrick publications (2)Pre-Crick publications (2) Facet Crick Pre-Crick Displaying 1 - 4 of 4Last updated : 28 March 2023 03:01 A human CD68 promoter-driven inducible cre-recombinase mouse line allows specific targeting of tissue resident macrophages Authors (5) Agata N RumianekBen Davies Keith M Channon David R Greaves Gareth SD Purvis Frontiers in Immunology Published 6 July 2022 Crick labs/ facilitiesGenetic Modification ServiceFull details Precisely tuned inhibition of HIF prolyl hydroxylases is key for cardioprotection after ischemia Authors (11) Aline Jatho Anke Zieseniss Katja Brechtel-Curth Atsushi Yamamoto Mathew L Coleman Ana M Vergel Leon Daniel BiggsBen Davies Chris W PughPeter Ratcliffe Dörthe M Katschinski Circulation Research Published 16 April 2021 Crick labsPeter RatcliffeFull details Systemic silencing of Phd2 causes reversible immune regulatory dysfunction Authors (25) Atsushi Yamamoto Joanna Hester Philip S Macklin Kento Kawai Masateru Uchiyama Daniel Biggs[...] Cheryl L Scudamore Elizabeth Soilleux Fadi IssaPeter Ratcliffe Chris W Pugh Journal of Clinical Investigation Published 3 September 2019 Crick labsPeter RatcliffeFull details A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia Authors (23) Julie Adam Ming Yang Christina Bauerschmidt Mitsuhiro Kitagawa Linda O'Flaherty Pratheesh Maheswaran[...]Peter Ratcliffe Mona El-Bahrawy Houman Ashrafian Tomoyoshi Soga Patrick J Pollard Cell Reports Published 30 May 2013 Crick labsPeter RatcliffeFull details
A human CD68 promoter-driven inducible cre-recombinase mouse line allows specific targeting of tissue resident macrophages Authors (5) Agata N RumianekBen Davies Keith M Channon David R Greaves Gareth SD Purvis Frontiers in Immunology Published 6 July 2022 Crick labs/ facilitiesGenetic Modification ServiceFull details
Precisely tuned inhibition of HIF prolyl hydroxylases is key for cardioprotection after ischemia Authors (11) Aline Jatho Anke Zieseniss Katja Brechtel-Curth Atsushi Yamamoto Mathew L Coleman Ana M Vergel Leon Daniel BiggsBen Davies Chris W PughPeter Ratcliffe Dörthe M Katschinski Circulation Research Published 16 April 2021 Crick labsPeter RatcliffeFull details
Systemic silencing of Phd2 causes reversible immune regulatory dysfunction Authors (25) Atsushi Yamamoto Joanna Hester Philip S Macklin Kento Kawai Masateru Uchiyama Daniel Biggs[...] Cheryl L Scudamore Elizabeth Soilleux Fadi IssaPeter Ratcliffe Chris W Pugh Journal of Clinical Investigation Published 3 September 2019 Crick labsPeter RatcliffeFull details
A role for cytosolic fumarate hydratase in urea cycle metabolism and renal neoplasia Authors (23) Julie Adam Ming Yang Christina Bauerschmidt Mitsuhiro Kitagawa Linda O'Flaherty Pratheesh Maheswaran[...]Peter Ratcliffe Mona El-Bahrawy Houman Ashrafian Tomoyoshi Soga Patrick J Pollard Cell Reports Published 30 May 2013 Crick labsPeter RatcliffeFull details
