Bethan Wallbank

The Toxoplasma Calcium-Dependent Kinase 3 has been shown to be important for rapid egress from the infected host-cell. A near-system wide quantitative phosphoproteome analysis has identified ~150 phosphorylation sites that are differentially phosphorylated between CDPK3 mutant and wild type parasites (Treeck et al., 2014). This revealed that CDPK3 is likely a regulator of basal biological processes in addition to controlling rapid egress. I am interested in identifying the role of CDPK3 that is unrelated to egress and how this feeds into the parasites basic biology.