Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
PhD student recruitment Applications for the 2023 PhD programme are now open until 12:00 noon (GMT) on Wednesday 22 March 2023
Coronavirus (COVID-19) research Crick researchers are working at the forefront of the scientific response to answer some of the most urgent questions about the SARS-CoV-2 pathogen, from how we can improve testing, to why it’s deadly in some people but causes no symptoms in others.
Breadcrumb Research A Z researchers Birgit Aerne PRINCIPAL LABORATORY RESEARCH SCIENTIST Tapon lab Apoptosis and Proliferation Control Laboratory Phone Number: +44 (0)20 3796 1748 Year published2021 (1)2017 (1)2015 (4) Facet Year publishedResearch topicsCell Cycle & Chromosomes (5)Chemical Biology & High Throughput (5)Developmental Biology (5)Gene Expression (5)Genetics & Genomics (5)Imaging (1)Model Organisms (5)Signalling & Oncogenes (5)Tumour Biology (5) Facet Research topicsPublication typeJournal article (6)Primary research (6) Facet Publication typeJournalCurrent Biology (2)Development (1)eLife (1)PLOS ONE (1)Proceedings of the National Academy of Sciences of the United States of America (1) Facet JournalCrick Pre-CrickCrick publications (6) Facet Crick Pre-Crick Displaying 1 - 6 of 6Last updated : 27 March 2023 03:30 RASSF8-mediated transport of Echinoid via the exocyst promotes Drosophila wing elongation and epithelial ordering Authors (8) Eunice HY Chan Yanxiang ZhouBirgit AerneMaxine HolderAnne WestonDavid BarryLucy CollinsonNicolas Tapon Development Published 15 October 2021 Crick labs/ facilitiesNic TaponLight MicroscopyElectron MicroscopyFull details Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division Authors (6) Jennifer J BanerjeeBirgit AerneMaxine Holder Simon Hauri Matthias GstaigerNicolas Tapon eLife Published 30 June 2017 Crick labs/ facilitiesNic TaponLight MicroscopyFull details The Hippo pathway core cassette regulates asymmetric cell division Authors (6) Alyona Keder Noemí Rives-QuintoBirgit Aerne Maribel FrancoNicolas Tapon Ana Carmena Current Biology Published 2 November 2015 Crick labsNic TaponFull details Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system Authors (3) Ieva GailiteBirgit AerneNicolas Tapon Proceedings of the National Academy of Sciences of the United States of America Published 15 September 2015 Crick labs/ facilitiesNic TaponStructural BiologyFull details Hippo stabilises its adaptor Salvador by antagonising the HECT ubiquitin ligase Herc4 Authors (4)Birgit Aerne Ieva Gailite David SimsNicolas Tapon PLOS ONE Published 30 June 2015 Crick labsNic TaponFull details Zyxin antagonizes the FERM protein expanded to couple F-actin and Yorkie-dependent organ growth Authors (5) Pedro GasparMaxine HolderBirgit Aerne Florence JanodyNicolas Tapon Current Biology Published 16 March 2015 Crick labsNic TaponFull details
RASSF8-mediated transport of Echinoid via the exocyst promotes Drosophila wing elongation and epithelial ordering Authors (8) Eunice HY Chan Yanxiang ZhouBirgit AerneMaxine HolderAnne WestonDavid BarryLucy CollinsonNicolas Tapon Development Published 15 October 2021 Crick labs/ facilitiesNic TaponLight MicroscopyElectron MicroscopyFull details
Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division Authors (6) Jennifer J BanerjeeBirgit AerneMaxine Holder Simon Hauri Matthias GstaigerNicolas Tapon eLife Published 30 June 2017 Crick labs/ facilitiesNic TaponLight MicroscopyFull details
The Hippo pathway core cassette regulates asymmetric cell division Authors (6) Alyona Keder Noemí Rives-QuintoBirgit Aerne Maribel FrancoNicolas Tapon Ana Carmena Current Biology Published 2 November 2015 Crick labsNic TaponFull details
Differential control of Yorkie activity by LKB1/AMPK and the Hippo/Warts cascade in the central nervous system Authors (3) Ieva GailiteBirgit AerneNicolas Tapon Proceedings of the National Academy of Sciences of the United States of America Published 15 September 2015 Crick labs/ facilitiesNic TaponStructural BiologyFull details
Hippo stabilises its adaptor Salvador by antagonising the HECT ubiquitin ligase Herc4 Authors (4)Birgit Aerne Ieva Gailite David SimsNicolas Tapon PLOS ONE Published 30 June 2015 Crick labsNic TaponFull details
Zyxin antagonizes the FERM protein expanded to couple F-actin and Yorkie-dependent organ growth Authors (5) Pedro GasparMaxine HolderBirgit Aerne Florence JanodyNicolas Tapon Current Biology Published 16 March 2015 Crick labsNic TaponFull details
