Cesira De Chiara

Lab: Mycobacterial Metabolism and Antibiotic Research Laboratory
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Job Title: Principal Laboratory Research Scientist

Displaying 1 - 7 of 7

Last updated : 24 November 2020 03:29

D-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition

Authors (9)

Cesira De Chiara
Miha Homšak
Gareth A Prosser
Holly Douglas
Acely Garza-Garcia
Geoff Kelly
Andrew G Purkiss
Edward W Tate
Luiz Pedro Carvalho

Nature Chemical Biology

Published 1 June 2020

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The mechanism of acetyl transfer catalyzed by Mycobacterium tuberculosis GlmU

Authors (8)

Peter Craggs
Stephane Mouilleron
Martin Rejzek
Cesira De Chiara
Robert J Young
Robert A Field
Argyrides Argyrou
Luiz Pedro Carvalho

Biochemistry

Published 19 June 2018

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Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

Authors (13)

Sarah Batson
Cesira De Chiara
Vita Majce
Adrian J Lloyd
Stanislav Gobec
Dean Rea
[...]
Katie J Simmons
Christopher G Dowson
Colin WG Fishwick
Luiz Pedro Carvalho
David I Roper

Nature Communications

Published 5 December 2017

Crick labs/ facilities

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Uncoupling conformational states from activity in an allosteric enzyme

Authors (9)

Nature Communications

Published 7 August 2017

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Conformational rigidity within plasticity promotes differential target recognition of nerve growth factor

Authors (9)

Francesca Paoletti
Cesira De Chiara
Geoff Kelly
Sonia Covaceuszach
Francesca Malerba
Robert Yan
Doriano Lamba
Antonino Cattaneo
Annalisa Pastore

Frontiers in Molecular Biosciences

Published 26 December 2016

Crick labs/ facilities

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Glutamate racemase is the primary target of β-chloro-ᴅ-alanine in Mycobacterium tuberculosis

Authors (7)

Gareth A Prosser
Anne Rodenburg
Hania Khoury
Cesira De Chiara
Steve Howell
Bram Snijders
Luiz Pedro Carvalho

Antimicrobial Agents and Chemotherapy

Published 1 October 2016

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Self-assembly and conformational heterogeneity of the AXH domain of ataxin-1: an unusual example of a chameleon fold

Authors (10)

Cesira De Chiara
M Rees
RP Menon
K Pauwels
C Lawrence
PV Konarev
DI Svergun
SR Martin
YW Chen
A Pastore

Biophysical Journal

Published 1 January 2013

Crick labs/ facilities

Structural Biology

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D-Cycloserine destruction by alanine racemase and the limit of irreversible inhibition

The mechanism of acetyl transfer catalyzed by Mycobacterium tuberculosis GlmU

Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine

Uncoupling conformational states from activity in an allosteric enzyme

Conformational rigidity within plasticity promotes differential target recognition of nerve growth factor

Glutamate racemase is the primary target of β-chloro-ᴅ-alanine in Mycobacterium tuberculosis

Self-assembly and conformational heterogeneity of the AXH domain of ataxin-1: an unusual example of a chameleon fold

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