Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
Postdoctoral clinical fellows Opportunities for postdoctoral clinicians to consolidate their research experience.
Breadcrumb Research A Z researchers Christophe Galichet Visiting Scientist Lovell-Badge lab Stem Cell Biology and Developmental Genetics Laboratory Email Address: Email Year published2022 (2)2021 (2)2012 (1)2010 (1) Facet Year publishedResearch topicsChemical Biology & High Throughput (2)Computational & Systems Biology (1)Developmental Biology (4)Genetics & Genomics (4)Genome Integrity & Repair (1)Model Organisms (4)Neurosciences (4)Stem Cells (4)Structural Biology & Biophysics (1)Tumour Biology (4) Facet Research topicsPublication typeJournal article (6) (-)Primary research (6) Facet Publication typeJournalDevelopmental Neurobiology (1)eLife (1)Genetics in Medicine (1)PLOS ONE (1)Proceedings of the National Academy of Sciences of the United States of America (1)Proceedings of the National Academy of Sciences of USA (1) Facet JournalCrick Pre-Crick (-)Crick publications (6) Facet Crick Pre-Crick Displaying 1 - 6 of 6Last updated : 23 April 2024 02:42 The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX Authors (5)Alessia CaramelloChristophe Galichet Miriam Llorian SopenaRobin Lovell-BadgeKarine Rizzoti Developmental Neurobiology Published 1 October 2022 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyBiological Research FacilityAdvanced SequencingFull details Pathogenic variants in RNPC3 are associated with hypopituitarism and primary ovarian insufficiency Authors (30) Leyla AkinKarine Rizzoti Louise C Gregory Beatriz Corredor Polona Le Quesne Stabej Hywel Williams[...] Luis A Pérez-Jurado Iain RobinsonRobin Lovell-Badge Jesús Argente Mehul T Dattani Genetics in Medicine Published 1 February 2022 Crick labs/ facilitiesRobin Lovell-BadgeStructural BiologyFull details SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice Authors (6)Veronica Moncho Amor Probir ChakravartyChristophe Galichet Ander MatheuRobin Lovell-BadgeKarine Rizzoti Proceedings of the National Academy of Sciences of USA Published 16 February 2021 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details Dentate gyrus development requires a cortical hem-derived astrocytic scaffold Authors (4)Alessia CaramelloChristophe GalichetKarine RizzotiRobin Lovell-Badge eLife Published 4 January 2021 Crick labs/ facilitiesRobin Lovell-BadgeLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis Authors (7) María Victoria Gómez-Gaviro Charlotte E Scott Abdul K Sesay Ander Matheu Sarah BoothChristophe GalichetRobin Lovell-Badge Proceedings of the National Academy of Sciences of the United States of America Published 9 January 2012 Crick labs/ facilitiesRobin Lovell-BadgeAdvanced SequencingFull details Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland Authors (3)Christophe GalichetRobin Lovell-BadgeKarine Rizzoti PLOS ONE Published 6 July 2010 Crick labsRobin Lovell-BadgeFull details
The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX Authors (5)Alessia CaramelloChristophe Galichet Miriam Llorian SopenaRobin Lovell-BadgeKarine Rizzoti Developmental Neurobiology Published 1 October 2022 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyBiological Research FacilityAdvanced SequencingFull details
Pathogenic variants in RNPC3 are associated with hypopituitarism and primary ovarian insufficiency Authors (30) Leyla AkinKarine Rizzoti Louise C Gregory Beatriz Corredor Polona Le Quesne Stabej Hywel Williams[...] Luis A Pérez-Jurado Iain RobinsonRobin Lovell-Badge Jesús Argente Mehul T Dattani Genetics in Medicine Published 1 February 2022 Crick labs/ facilitiesRobin Lovell-BadgeStructural BiologyFull details
SOX2 is required independently in both stem and differentiated cells for pituitary tumorigenesis in p27-null mice Authors (6)Veronica Moncho Amor Probir ChakravartyChristophe Galichet Ander MatheuRobin Lovell-BadgeKarine Rizzoti Proceedings of the National Academy of Sciences of USA Published 16 February 2021 Crick labs/ facilitiesRobin Lovell-BadgeBioinformatics and BiostatisticsLight MicroscopyFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Dentate gyrus development requires a cortical hem-derived astrocytic scaffold Authors (4)Alessia CaramelloChristophe GalichetKarine RizzotiRobin Lovell-Badge eLife Published 4 January 2021 Crick labs/ facilitiesRobin Lovell-BadgeLight MicroscopyExperimental HistopathologyBiological Research FacilityFull details
Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis Authors (7) María Victoria Gómez-Gaviro Charlotte E Scott Abdul K Sesay Ander Matheu Sarah BoothChristophe GalichetRobin Lovell-Badge Proceedings of the National Academy of Sciences of the United States of America Published 9 January 2012 Crick labs/ facilitiesRobin Lovell-BadgeAdvanced SequencingFull details
Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland Authors (3)Christophe GalichetRobin Lovell-BadgeKarine Rizzoti PLOS ONE Published 6 July 2010 Crick labsRobin Lovell-BadgeFull details