Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
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Breadcrumb Research A Z researchers Colin Ratcliffe Postdoctoral Fellow Sahai lab Tumour Cell Biology Laboratory Qualifications and history 2018 McGill University, Canada Doctor of PhilosophyYear published2023 (1)2021 (1)2020 (1) Facet Year publishedResearch topicsCell Biology (3)Cell Cycle & Chromosomes (1)Chemical Biology & High Throughput (3)Computational & Systems Biology (3)Gene Expression (1) (-)Genetics & Genomics (3)Genome Integrity & Repair (3)Human Biology & Physiology (1)Imaging (3)Model Organisms (3)Stem Cells (1)Tumour Biology (3) Facet Research topicsPublication typeJournal article (3)Primary research (3) Facet Publication typeJournalCancer Cell (1)Cancers (1)Nature Cell Biology (1) Facet JournalCrick Pre-CrickCrick publications (3) Facet Crick Pre-Crick Displaying 1 - 3 of 3Last updated : 20 April 2024 02:03 Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia Authors (15)Ioannis LoukasFabrizio SimeoniMarta MilanPaolo Inglese Harshil PatelRobert Goldstone[...] Wenhao TangColin RatcliffeErik Sahai Vahid ShahrezaeiPaola Scaffidi Cancer Cell Published 9 January 2023 Crick labs/ facilitiesPaola ScaffidiErik SahaiBioinformatics and BiostatisticsStructural BiologyLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details EphB6 regulates TFEB-lysosomal pathway and survival of disseminated indolent breast cancer cells Authors (11) Manuela Zangrossi Patrizia Romani Probir ChakravartyColin RatcliffeSteven Hooper Martina Dori Mattia Forcato Silvio Bicciato Sirio DupontErik Sahai Marco Montagner Cancers Published 3 March 2021 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination Authors (12) Marco Montagner Rahul BhomeSteven Hooper Probir Chakravarty Xiao Qin Jahangir Sufi[...]Colin Ratcliffe Yutaka Naito Arianna Pocaterra Christopher J TapeErik Sahai Nature Cell Biology Published 1 March 2020 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details
Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia Authors (15)Ioannis LoukasFabrizio SimeoniMarta MilanPaolo Inglese Harshil PatelRobert Goldstone[...] Wenhao TangColin RatcliffeErik Sahai Vahid ShahrezaeiPaola Scaffidi Cancer Cell Published 9 January 2023 Crick labs/ facilitiesPaola ScaffidiErik SahaiBioinformatics and BiostatisticsStructural BiologyLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
EphB6 regulates TFEB-lysosomal pathway and survival of disseminated indolent breast cancer cells Authors (11) Manuela Zangrossi Patrizia Romani Probir ChakravartyColin RatcliffeSteven Hooper Martina Dori Mattia Forcato Silvio Bicciato Sirio DupontErik Sahai Marco Montagner Cancers Published 3 March 2021 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details
Crosstalk with lung epithelial cells regulates Sfrp2-mediated latency in breast cancer dissemination Authors (12) Marco Montagner Rahul BhomeSteven Hooper Probir Chakravarty Xiao Qin Jahangir Sufi[...]Colin Ratcliffe Yutaka Naito Arianna Pocaterra Christopher J TapeErik Sahai Nature Cell Biology Published 1 March 2020 Crick labs/ facilitiesErik SahaiBioinformatics and BiostatisticsFlow CytometryExperimental HistopathologyCell ServicesBiological Research FacilityAdvanced SequencingFull details