Conor Henry received his B.A. (Mod.) in Genetics (2009) from Trinity College Dublin. Conor obtained his PhD (2015) from Trinity College Dublin under the supervision of Professor Seamus J. Martin. During his PhD he focused on how cytokines that are associated with tissue damage regulate inflammatory signaling. He was the first to discover proteases (molecular scissors) that switch on IL-36 cytokines (IL-1 family cytokines) during tissue injury to promote inflammation. His PhD work also described how death receptors of the TNF-superfamily (CD95/TRAIL-R) promote inflammatory signaling.
Conor subsequently joined the group of Professor Caetano Reis e Sousa at the Francis Crick Institute in London, UK, as a Postdoctoral Fellow. With funding from a Long-term FEBS fellowship (2017) and a Marie Skłodowska-Curie Actions Individual Fellowship (2018), he identified damage signals derived from the cytoskeleton that is sensed to coordinate repair responses. His current work focuses on molecular mechanisms that permit dendritic cells to acquire and process extracellular material from dying cancer cells to boost anti-cancer immunity.