Cristina is a Clinical Geneticist and Wellcome Trust Clinical Research Career Development Fellow. Her research focuses on understanding how altered early brain development leads to intellectual disability (ID). Cristina aims to understand the role of BAF swi/snf chromatin remodellers in neurodevelopment, and the mechanism by which their dysfunction causes ID. In Francois Guillemot’s lab, she is using human neural stem cell models to interrogate these mechanisms. Aligned with this, Cristina is leading a clinical study – BUILD (BAF complex & related genes underlying intellectual disability) - a collaboration between Great Ormond Street Hospital, the Francis Crick Institute, and King’s College London aimed at providing a deeper understanding of these conditions clinically and biologically.