Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
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Breadcrumb Research A Z researchers Cristina Dias Visiting Scientist Guillemot lab Neural Stem Cell Biology Laboratory Email Address: Email LinksKCL profileYear published2023 (1)2022 (1)2021 (1)2020 (1)2019 (1)2017 (1) Facet Year publishedResearch topicsChemical Biology & High Throughput (1)Computational & Systems Biology (1)Developmental Biology (6)Gene Expression (6)Genetics & Genomics (6)Genome Integrity & Repair (1)Human Biology & Physiology (1)Model Organisms (6)Neurosciences (6)Stem Cells (6)Tumour Biology (1) Facet Research topicsPublication typeCommentary (1)Editorial (1)Journal article (6)Primary research (4) Facet Publication typeJournalEMBO Journal (1)Frontiers in Neuroscience (1)Genes and Development (1)Genetics in Medicine (1)Pediatrics (1)Stem Cell Research (1) Facet JournalCrick Pre-CrickCrick publications (6) Facet Crick Pre-Crick Displaying 1 - 6 of 6Last updated : 18 April 2024 02:44 Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation Authors (12)Oana PaunYu Xuan Tan Harshil Patel Stephanie StrohbueckerAvinash GhanateClementina Cobolli Gigli[...]Lina GerontogianniRobert GoldstoneSiew-Lan AngFrancois GuillemotCristina Dias Genes and Development Published 1 March 2023 Crick labs/ facilitiesFrancois GuillemotBioinformatics and BiostatisticsProteomicsLight MicroscopyHuman Embryonic Stem CellFlow CytometryAdvanced SequencingFull details Editorial: Transcription and chromatin regulators in neurodevelopmental disorders Authors (4) Debbie LC van den Berg Julian Ik-Tsen Heng Alessandro SessaCristina Dias Frontiers in Neuroscience Published 16 September 2022 Crick labsFrancois GuillemotFull details Generation of an iPSC line (CRICKi001-A) from an individual with a germline SMARCA4 missense mutation and autism spectrum disorder Authors (5)Liani Gasparini DevitoLyn Healy Shehla MohammedFrancois GuillemotCristina Dias Stem Cell Research Published 1 May 2021 Crick labs/ facilitiesFrancois GuillemotHuman Embryonic Stem CellCell ServicesAdvanced SequencingFull details De novo SMARCA2 variants clustered outside the helicase domain cause a new recognizable syndrome with intellectual disability and blepharophimosis distinct from Nicolaides-Baraitser syndrome Authors (48) Gerarda Cappuccio Camille Sayou Pauline Le Tanno Emilie Tisserant Ange-Line Bruel Sara El Kennani[...] Bekim Sadikovic Julien Thevenon Jérôme Govin Antonio Vitobello Nicola Brunetti-Pierri Genetics in Medicine Published 1 November 2020 Crick labsFrancois GuillemotFull details Inflammatory arthritis as a possible feature of Coffin-Siris syndrome Authors (7) Sonia Melo GomesCristina Dias Ebun Omoyinmi Sandrine Compeyrot-Lacassagne Nigel Klein Neil J Sebire Paul Brogan Pediatrics Published 1 July 2019 Crick labsFrancois GuillemotFull details Revealing the inner workings of organoids Authors (2)Cristina DiasFrancois Guillemot EMBO Journal Published 24 April 2017 Crick labsFrancois GuillemotFull details Related content Francois Guillemot | BUILD clinical study BUILD (BAF complex & related genes underlying intellectual disability) is a study focused on understanding intellectual developmental disorders caused by mutations in genes that encode the BAF swi/snf chromatin remodelling complex and associated proteins.
Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation Authors (12)Oana PaunYu Xuan Tan Harshil Patel Stephanie StrohbueckerAvinash GhanateClementina Cobolli Gigli[...]Lina GerontogianniRobert GoldstoneSiew-Lan AngFrancois GuillemotCristina Dias Genes and Development Published 1 March 2023 Crick labs/ facilitiesFrancois GuillemotBioinformatics and BiostatisticsProteomicsLight MicroscopyHuman Embryonic Stem CellFlow CytometryAdvanced SequencingFull details
Editorial: Transcription and chromatin regulators in neurodevelopmental disorders Authors (4) Debbie LC van den Berg Julian Ik-Tsen Heng Alessandro SessaCristina Dias Frontiers in Neuroscience Published 16 September 2022 Crick labsFrancois GuillemotFull details
Generation of an iPSC line (CRICKi001-A) from an individual with a germline SMARCA4 missense mutation and autism spectrum disorder Authors (5)Liani Gasparini DevitoLyn Healy Shehla MohammedFrancois GuillemotCristina Dias Stem Cell Research Published 1 May 2021 Crick labs/ facilitiesFrancois GuillemotHuman Embryonic Stem CellCell ServicesAdvanced SequencingFull details
De novo SMARCA2 variants clustered outside the helicase domain cause a new recognizable syndrome with intellectual disability and blepharophimosis distinct from Nicolaides-Baraitser syndrome Authors (48) Gerarda Cappuccio Camille Sayou Pauline Le Tanno Emilie Tisserant Ange-Line Bruel Sara El Kennani[...] Bekim Sadikovic Julien Thevenon Jérôme Govin Antonio Vitobello Nicola Brunetti-Pierri Genetics in Medicine Published 1 November 2020 Crick labsFrancois GuillemotFull details
Inflammatory arthritis as a possible feature of Coffin-Siris syndrome Authors (7) Sonia Melo GomesCristina Dias Ebun Omoyinmi Sandrine Compeyrot-Lacassagne Nigel Klein Neil J Sebire Paul Brogan Pediatrics Published 1 July 2019 Crick labsFrancois GuillemotFull details
Revealing the inner workings of organoids Authors (2)Cristina DiasFrancois Guillemot EMBO Journal Published 24 April 2017 Crick labsFrancois GuillemotFull details
Francois Guillemot | BUILD clinical study BUILD (BAF complex & related genes underlying intellectual disability) is a study focused on understanding intellectual developmental disorders caused by mutations in genes that encode the BAF swi/snf chromatin remodelling complex and associated proteins.
