Dhira Joshi

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease

Authors (22)

Biochemical Journal

Published 16 July 2021

Crick labs/ facilities

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An improved method for the incorporation of fluoromethyl ketones into solid phase peptide synthesis techniques

Authors (6)

RSC Advances: an international journal to further the chemical sciences

Published 8 June 2021

Crick labs/ facilities

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Phosphorylation of the LIR domain of SCOC modulates ATG8 binding affinity and specificity

Authors (15)

Martina Wirth
Stephane Mouilleron
Wenxin Zhang
Eva Sjottem
Yakubu Princely Abudu
Ashish Jain
[...]
Rebecca Lee
Dhira Joshi
Nicola O'Reilly
Terje Johansen
Sharon Tooze

Journal of Molecular Biology

Published 25 June 2021

Crick labs/ facilities

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Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization

Authors (11)

Ilaria Gori
Roger George
Andrew G Purkiss
Stephanie Strohbuecker
Rebecca A Randall
Roksana Ogrodowicz
Virginie Carmignac
Laurence Faivre
Dhira Joshi
Svend Kjaer
Caroline Hill

eLife

Published 8 January 2021

Crick labs/ facilities

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Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

Authors (47)

Kevin Ng
Nikhil Faulkner
Georgina H Cornish
Annachiara Rosa
Ruth Harvey
Saira Hussain
[...]
Steve Gamblin
Laura E Mccoy
Peter Cherepanov
Eleni Nastouli
George Kassiotis

Science

Published 11 December 2020

Crick labs/ facilities

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Glypicans shield the Wnt lipid moiety to enable signalling at a distance

Authors (10)

Ian Mcgough
Luca Vecchia
Benjamin Bishop
Tomas Malinauskas
Karen Beckett
Dhira Joshi
Nicola O'Reilly
Christian Siebold
E Yvonne Jones
Jean-Paul Vincent

Nature

Published 3 September 2020

Crick labs/ facilities

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The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition

Authors (12)

Joanna R Kelly
Silvia Martini
Nicola Brownlow
Dhira Joshi
Stefania Federico
Shirin Jamshidi
[...]
Nicola Lockwood
Khondaker Miraz Rahman
Franca Fraternali
Peter Parker
Tanya Soliman

Nature Communications

Published 13 March 2020

Crick labs/ facilities

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Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins

Authors (9)

Nature Communications

Published 3 May 2019

Crick labs/ facilities

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VE-cadherin-mediated epigenetic regulation of endothelial gene expression

Authors (21)

Marco F Morini
Costanza Giampietro
Monica Corada
Federica Pisati
Elisa Lavarone
Sara I Cunha
[...]
Ugo Cavallaro
Diego Pasini
Dinis Calado
Elisabetta Dejana
Andrea Taddei

Circulation Research

Published 19 January 2018

Crick labs/ facilities

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Differential recognition preferences of the three Src homology 3 (SH3) domains from the adaptor CD2-associated protein (CD2AP) and direct association with Ras and Rab interactor 3 (RIN3)

Authors (14)

Evgenia Rouka
Philip C Simister
Melanie Janning
Joerg Kumbrink
Tassos Konstantinou
João RC Muniz
[...]
Brigitte Ritter
Stefan Knapp
Frank von Delft
Kathrin H Kirsch
Stephan M Feller

Journal of Biological Chemistry

Published 16 October 2015

Crick labs/ facilities

Peptide Chemistry

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Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex

Authors (10)

Zuzana Hořejší
Lasse Stach
Thomas G Flower
Dhira Joshi
Helen Flynn
J Mark Skehel
Nicola O'Reilly
Roksana Ogrodowicz
Stephen J Smerdon
Simon Boulton

Cell Reports

Published 18 March 2014

Crick labs/ facilities

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Coronavirus (COVID-19) response

Vacancies

A drop of hope

Coronavirus (COVID-19) research

About us

Dhira Joshi

STP DEPUTY

Peptide Chemistry

Year published

Research topics

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Journal

Crick Pre-Crick

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease

An improved method for the incorporation of fluoromethyl ketones into solid phase peptide synthesis techniques

Phosphorylation of the LIR domain of SCOC modulates ATG8 binding affinity and specificity

Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

Glypicans shield the Wnt lipid moiety to enable signalling at a distance

The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition

Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins

VE-cadherin-mediated epigenetic regulation of endothelial gene expression

Differential recognition preferences of the three Src homology 3 (SH3) domains from the adaptor CD2-associated protein (CD2AP) and direct association with Ras and Rab interactor 3 (RIN3)

Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex

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