Donald Benton

Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein

Authors (9)

Antoni Wrobel
Donald Benton
Saira Hussain
Ruth Harvey
Stephen R Martin
Chloe Roustan
Peter Rosenthal
John J Skehel
Steve Gamblin

Nature Communications

Published 21 October 2020

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Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

Authors (8)

Donald Benton
Antoni Wrobel
Pengqi Xu
Chloe Roustan
Stephen R Martin
Peter Rosenthal
John J Skehel
Steve Gamblin

Nature

Published 17 September 2020

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SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

Authors (8)

Antoni Wrobel
Donald Benton
Pengqi Xu
Chloe Roustan
Stephen R Martin
Peter Rosenthal
John J Skehel
Steve Gamblin

Nature Structural & Molecular Biology

Published 1 August 2020

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Structural transitions in influenza haemagglutinin at membrane fusion pH

Authors (4)

Nature

Published 2 July 2020

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Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion

Authors (11)

Thomas P Peacock
Donald Benton
Jean-Remy Sadeyen
Pengxiang Chang
Joshua E Sealy
Juliet E Bryant
Stephen R Martin
Holly Shelton
John McCauley
Wendy S Barclay
Munir Iqbal

Emerging Microbes & Infections

Published 15 January 2019

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Influenza hemagglutinin membrane anchor

Authors (13)

Donald Benton
Andrea Nans
Lesley Calder
Jack Turner
Ursula Neu
Yi Pu Lin
[...]
Davide Corti
Antonio Lanzavecchia
Steve Gamblin
Peter Rosenthal
John J Skehel

Proceedings of the National Academy of Sciences of the United States of America

Published 17 September 2018

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Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis

Authors (5)

PLOS Pathogens

Published 15 June 2018

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Immune escape variants of H9N2 influenza viruses containing deletions at the hemagglutinin receptor binding site retain fitness in vivo and display enhanced zoonotic characteristics

Authors (11)

Thomas P Peacock
Donald Benton
Joe James
Jean-Remy Sadeyen
Pengxiang Chang
Joshua E Sealy
Juliet E Bryant
Stephen R Martin
Holly Shelton
Wendy S Barclay
Munir Iqbal

Journal of Virology

Published 26 June 2017

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Dual recognition element lateral flow assay toward multiplex strain specific influenza virus detection

Authors (6)

Thao T Le
Pengxiang Chang
Donald Benton
John McCauley
Munir Iqbal
Anthony EG Cass

Analytical Chemistry

Published 30 May 2017

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Role of neuraminidase in influenza A(H7N9) receptor binding

Authors (4)

Donald Benton
Stephen A Wharton
Stephen R Martin
John McCauley

Journal of Virology

Published 12 May 2017

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The role of the B-allele of the influenza A virus segment 8 in setting mammalian host range and pathogenicity

Authors (20)

Matthew L Turnbull
Helen M Wise
Marlynne Q Nicol
Nikki Smith
Rebecca L Dunfee
Philippa M Beard
[...]
Jeffery K Taubenberger
Samantha J Lycett
Michael P Weekes
Bernadette M Dutia
Paul Digard

Journal of Virology

Published 15 October 2016

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Identification of low- and high-impact hemagglutinin amino acid substitutions that drive antigenic drift of influenza A(H1N1) viruses

Authors (10)

William T Harvey
Donald Benton
Victoria Gregory
James PJ Hall
Rodney S Daniels
Trevor Bedford
Daniel T Haydon
Alan J Hay
John McCauley
Richard Reeve

PLOS Pathogens

Published 8 April 2016

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Biophysical measurement of the balance of influenza A hemagglutinin and neuraminidase activities

Authors (4)

Donald Benton
Stephen R Martin
Stephen A Wharton
John McCauley

Journal of Biological Chemistry

Published 6 March 2015

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Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein

Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion

SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

Structural transitions in influenza haemagglutinin at membrane fusion pH

Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion

Influenza hemagglutinin membrane anchor

Murine leukemia virus p12 tethers the capsid-containing pre-integration complex to chromatin by binding directly to host nucleosomes in mitosis

Immune escape variants of H9N2 influenza viruses containing deletions at the hemagglutinin receptor binding site retain fitness in vivo and display enhanced zoonotic characteristics

Dual recognition element lateral flow assay toward multiplex strain specific influenza virus detection

Role of neuraminidase in influenza A(H7N9) receptor binding

The role of the B-allele of the influenza A virus segment 8 in setting mammalian host range and pathogenicity

Identification of low- and high-impact hemagglutinin amino acid substitutions that drive antigenic drift of influenza A(H1N1) viruses

Biophysical measurement of the balance of influenza A hemagglutinin and neuraminidase activities

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