Eugenia Almacellas I Canals

Eugenia graduated in Biomedicine (Cancer Biology) at the University of Barcelona in 2014. In 2018, she completed her PhD in the Cancer Metabolism Laboratory co-directed by Dr. Albert Tauler and Dr. Caroline Mauvezin (IDIBELL,Barcelona). Focusing on the implication of lysosomes in cancer cell biology, she showed how the E2F1 transcription factor activates mTORC1 through the glycolytic enzymes PFK1 and PFKFB3 at the lysosome surface. In parallel, she specialized in the study of autophagy in mitotic cells where she uncovered the importance of lysosomal degradation for accurate chromosomal segregation and described a novel nuclear phenotype (the toroidal nucleus) as a novel biomarker for genomic instability.

After her PhD in Barcelona, she joined the laboratory of Sharon Tooze, where she is studying signaling cascades governing membrane trafficking routes. This state-of-the-art project involves a broad technical landscape, from confocal microscopy and biochemistry to mass spectrometry. Eugenia is a highly collaborative and curiosity-driven researcher, who will always be open to a scientific discussion in front of a cup of coffee. She enjoys ideating novel approaches to tackle exciting scientific questions and can spend hours working on image acquisition and analysis.