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Breadcrumb Research A Z researchers Frankie Houghton Visiting Scientist McDonald lab Signalling and Structural Biology Laboratory Email Address: Email Year published2023 (2)2021 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (2)Chemical Biology & High Throughput (3)Computational & Systems Biology (2)Gene Expression (1)Genetics & Genomics (1)Model Organisms (1)Signalling & Oncogenes (3) (-)Structural Biology & Biophysics (3)Tumour Biology (1) Facet Research topicsPublication typeJournal article (3)Primary research (3) Facet Publication typeJournalNature Communications (1)Scientific Reports (1)Structure (1) Facet JournalCrick Pre-CrickCrick publications (3) Facet Crick Pre-Crick Displaying 1 - 3 of 3Last updated : 28 March 2024 03:32 Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly Authors (8)Frankie HoughtonSarah Adams AS RíosLaura Masino AG PurkissDavid Briggs F LeddaNeil McDonald Nature Communications Published 20 November 2023 Crick labs/ facilitiesNeil McDonaldStructural BiologyFlow CytometryBiological Research FacilityFull details Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α Authors (18)Soly Ismail Stephen R MartinRoger GeorgeFrankie HoughtonGeoff KellyRaphael Chaleil[...] Ning Sze HuiMiriam Molina ArcasDavid Hancock Ali TavassoliJulian Downward Scientific Reports Published 2 February 2023 Crick labs/ facilitiesJulian DownwardPaul BatesStructural BiologyMRC Biomedical NMR CentreFull details A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing Authors (14)Sarah Adams Andrew G Purkiss Phillip P KnowlesAndrea NansDavid BriggsAnnabel Borg[...] Aaron J Borg Pauline B McIntoshFrankie HoughtonSvend KjaerNeil McDonald Structure Published 1 July 2021 Crick labs/ facilitiesNeil McDonaldStructural BiologyProteomicsElectron MicroscopyFull details
Architecture and regulation of a GDNF-GFRα1 synaptic adhesion assembly Authors (8)Frankie HoughtonSarah Adams AS RíosLaura Masino AG PurkissDavid Briggs F LeddaNeil McDonald Nature Communications Published 20 November 2023 Crick labs/ facilitiesNeil McDonaldStructural BiologyFlow CytometryBiological Research FacilityFull details
Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α Authors (18)Soly Ismail Stephen R MartinRoger GeorgeFrankie HoughtonGeoff KellyRaphael Chaleil[...] Ning Sze HuiMiriam Molina ArcasDavid Hancock Ali TavassoliJulian Downward Scientific Reports Published 2 February 2023 Crick labs/ facilitiesJulian DownwardPaul BatesStructural BiologyMRC Biomedical NMR CentreFull details
A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing Authors (14)Sarah Adams Andrew G Purkiss Phillip P KnowlesAndrea NansDavid BriggsAnnabel Borg[...] Aaron J Borg Pauline B McIntoshFrankie HoughtonSvend KjaerNeil McDonald Structure Published 1 July 2021 Crick labs/ facilitiesNeil McDonaldStructural BiologyProteomicsElectron MicroscopyFull details