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Breadcrumb Research A-Z researchers George Pobegalov Affiliated Researcher Molodtsov lab Mechanobiology and Biophysics Laboratory Email Address: Crick email Email Year published 2026 (1) 2025 (1) 2024 (4) 2023 (2) 2021 (1) 2014 (1) Facet Year published Research topics Biochemistry & Proteomics (3) Cell Biology (6) Cell Cycle & Chromosomes (5) Computational & Systems Biology (3) Gene Expression (1) Genetics & Genomics (4) Imaging (4) Microfabrication & Bioengineering (4) Model Organisms (4) Structural Biology & Biophysics (5) Facet Research topics Crick Pre-Crick Crick publications (9) Pre-Crick publications (1) Facet Crick Pre-Crick Publication type Dataset (1) Journal article (7) Preprint (2) Primary research (7) Facet Publication type Journal BioRxiv (2) eLife (1) Molecular Cell (1) Nature Communications (2) Nature Structural and Molecular Biology (1) Structure (1) The EMBO Journal (2) Facet Journal Displaying 1 - 10 of 10Last updated : 16 August 2026 03:38 Symmetry and force response of cohesin loop extrusion are determined by diffusion of its motor and anchor domains Preprint Authors (7) George Pobegalov Runze Sha Oleg Dobrokhotov Torahiko Higashi Chris A Brackley Frank Uhlmann Maxim Molodtsov bioRxiv Published 10 June 2026 Crick labs Frank Uhlmann Maxim Molodtsov Full details Bending friction: a new mechanism of dissipation within DNA explains its slow looping dynamics Preprint Authors (3) George Pobegalov Maxim Molodtsov Bhavin S Khatri bioRxiv Published 16 July 2025 Crick labs Maxim Molodtsov Full details Force-transducing molecular ensembles at growing microtubule tips control mitotic spindle size Authors (6) Lee-Ya Chu Daniel Stedman Julian Gannon Susan Cox George Pobegalov Maxim Molodtsov Nature Communications Published 14 November 2024 Crick labs/ facilities Maxim Molodtsov Light Microscopy Full details BioStudies deposit S-SCDT-10_1038-S44318-024-00202-5: An extrinsic motor directs chromatin loop formation by cohesin Authors (5) Thomas Guerin Christopher Barrington George Pobegalov Maxim Molodtsov Frank Uhlmann BioStudies Published 19 September 2024 Crick labs/ facilities Frank Uhlmann Maxim Molodtsov Bioinformatics and Biostatistics Scientific computing Genomics Full details An extrinsic motor directs chromatin loop formation by cohesin Authors (5) Thomas Guerin Christopher Barrington George Pobegalov Maxim Molodtsov Frank Uhlmann The EMBO Journal Published 1 October 2024 Crick labs/ facilities Frank Uhlmann Maxim Molodtsov Bioinformatics and Biostatistics Scientific computing Genomics Full details Mechanical disengagement of the cohesin ring Authors (6) Martina Richeldi George Pobegalov Torahiko Higashi Karolina Gmurczyk Frank Uhlmann Maxim Molodtsov Nature Structural and Molecular Biology Published 1 January 2024 Crick labs Frank Uhlmann Maxim Molodtsov Full details Establishment of dsDNA-dsDNA interactions by the condensin complex Authors (8) Tony Tang George Pobegalov Hideki Tanizawa Zhuo A Chen Juri Rappsilber Maxim Molodtsov Ken-ichi Noma Frank Uhlmann Molecular Cell Published 1 November 2023 Crick labs/ facilities Frank Uhlmann Maxim Molodtsov Fermentation Bioinformatics and Biostatistics Full details Single cohesin molecules generate force by two distinct mechanisms Authors (4) George Pobegalov Lee-Ya Chu Jan-Michael Peters Maxim Molodtsov Nature Communications Published 4 July 2023 Crick labs/ facilities Maxim Molodtsov Electron Microscopy Full details A Brownian ratchet model for DNA loop extrusion by the cohesin complex Authors (5) Torahiko Higashi George Pobegalov Tony Tang Maxim Molodtsov Frank Uhlmann eLife Published 26 July 2021 Crick labs/ facilities Frank Uhlmann Maxim Molodtsov Structural Biology Full details Lytic water dynamics reveal evolutionarily conserved mechanisms of ATP hydrolysis by TIP49 AAA+ ATPases Authors (11) Arina Afanasyeva Angela Hirtreiter Anne Schreiber Dina Grohmann George Pobegalov Adam R McKay Irina Tsaneva Michael Petukhov Emmanuel Käs Mikhail Grigoriev Finn Werner Structure Published 8 April 2014 Crick labs Anne Schreiber Full details
Symmetry and force response of cohesin loop extrusion are determined by diffusion of its motor and anchor domains Preprint Authors (7) George Pobegalov Runze Sha Oleg Dobrokhotov Torahiko Higashi Chris A Brackley Frank Uhlmann Maxim Molodtsov bioRxiv Published 10 June 2026 Crick labs Frank Uhlmann Maxim Molodtsov Full details
Bending friction: a new mechanism of dissipation within DNA explains its slow looping dynamics Preprint Authors (3) George Pobegalov Maxim Molodtsov Bhavin S Khatri bioRxiv Published 16 July 2025 Crick labs Maxim Molodtsov Full details
Force-transducing molecular ensembles at growing microtubule tips control mitotic spindle size Authors (6) Lee-Ya Chu Daniel Stedman Julian Gannon Susan Cox George Pobegalov Maxim Molodtsov Nature Communications Published 14 November 2024 Crick labs/ facilities Maxim Molodtsov Light Microscopy Full details
BioStudies deposit S-SCDT-10_1038-S44318-024-00202-5: An extrinsic motor directs chromatin loop formation by cohesin Authors (5) Thomas Guerin Christopher Barrington George Pobegalov Maxim Molodtsov Frank Uhlmann BioStudies Published 19 September 2024 Crick labs/ facilities Frank Uhlmann Maxim Molodtsov Bioinformatics and Biostatistics Scientific computing Genomics Full details
An extrinsic motor directs chromatin loop formation by cohesin Authors (5) Thomas Guerin Christopher Barrington George Pobegalov Maxim Molodtsov Frank Uhlmann The EMBO Journal Published 1 October 2024 Crick labs/ facilities Frank Uhlmann Maxim Molodtsov Bioinformatics and Biostatistics Scientific computing Genomics Full details
Mechanical disengagement of the cohesin ring Authors (6) Martina Richeldi George Pobegalov Torahiko Higashi Karolina Gmurczyk Frank Uhlmann Maxim Molodtsov Nature Structural and Molecular Biology Published 1 January 2024 Crick labs Frank Uhlmann Maxim Molodtsov Full details
Establishment of dsDNA-dsDNA interactions by the condensin complex Authors (8) Tony Tang George Pobegalov Hideki Tanizawa Zhuo A Chen Juri Rappsilber Maxim Molodtsov Ken-ichi Noma Frank Uhlmann Molecular Cell Published 1 November 2023 Crick labs/ facilities Frank Uhlmann Maxim Molodtsov Fermentation Bioinformatics and Biostatistics Full details
Single cohesin molecules generate force by two distinct mechanisms Authors (4) George Pobegalov Lee-Ya Chu Jan-Michael Peters Maxim Molodtsov Nature Communications Published 4 July 2023 Crick labs/ facilities Maxim Molodtsov Electron Microscopy Full details
A Brownian ratchet model for DNA loop extrusion by the cohesin complex Authors (5) Torahiko Higashi George Pobegalov Tony Tang Maxim Molodtsov Frank Uhlmann eLife Published 26 July 2021 Crick labs/ facilities Frank Uhlmann Maxim Molodtsov Structural Biology Full details
Lytic water dynamics reveal evolutionarily conserved mechanisms of ATP hydrolysis by TIP49 AAA+ ATPases Authors (11) Arina Afanasyeva Angela Hirtreiter Anne Schreiber Dina Grohmann George Pobegalov Adam R McKay Irina Tsaneva Michael Petukhov Emmanuel Käs Mikhail Grigoriev Finn Werner Structure Published 8 April 2014 Crick labs Anne Schreiber Full details
