
James Macrae
STP LEAD
James completed a PhD on structural glycobiology in trypanosomatid parasites at the University of Dundee, before moving to the University of Melbourne in 2006.
Here, he expanded these interests into developing novel techniques in order to study the metabolism of apicomplexan parasites, including Toxoplasma gondii and the malaria parasite Plasmodium falciparum. This mass spectrometry-based metabolism research has now grown into a field in its own right – metabolomics.
Since 2013 James has been of Head of Metabolomics at the Francis Crick Institute, where he develops new tools for metabolomics research in a number of areas (e.g. cancer metabolism, heart disease, mitochondrial dysfunction), while maintaining interests in host-parasite metabolism.
Qualifications and history
Year published
Research topics
- Biochemistry & Proteomics (48)
- Cell Biology (49)
- Cell Cycle & Chromosomes (14)
- Chemical Biology & High Throughput (28)
- Computational & Systems Biology (49)
- Developmental Biology (48)
- Gene Expression (9)
- Genetics & Genomics (25)
- Genome Integrity & Repair (21)
- Human Biology & Physiology (48)
- Imaging (15)
- Immunology (47)
- Infectious Disease (47)
- Metabolism (48)
- Microfabrication & Bioengineering (3)
- Model Organisms (33)
- Neurosciences (20)
- Signalling & Oncogenes (48)
- Stem Cells (22)
- Structural Biology & Biophysics (18)
- Synthetic Biology (7)
- Tumour Biology (49)
Journal
- Angewandte Chemie International Edition (1)
- Antimicrobial Agents and Chemotherapy (1)
- BMC Biology (1)
- British Journal of Cancer (1)
- Cancer Cell (2)
- Cell (1)
- Cell Host & Microbe (2)
- Cell Reports (1)
- Cell Reports Medicine (1)
- Cellular Microbiology (1)
- Communications Biology (1)
- Current Biology (1)
- Current Pharmaceutical Design (1)
- Developmental Cell (1)
- Diabetes (1)
- eLife (1)
- Environmental Pollution (1)
- Environmental Science & Technology (1)
- FEBS Journal (2)
- Frontiers in Cellular and Infection Microbiology (1)
- Human Molecular Genetics (1)
- Immunity (1)
- Journal of Biological Chemistry (2)
- Journal of Clinical Investigation (1)
- Methods in Molecular Biology (1)
- Molecular Biology and Evolution (1)
- Molecular Microbiology (2)
- Molecular Systems Biology (1)
- Nature Biotechnology (1)
- Nature Cancer (3)
- Nature Cell Biology (1)
- Nature Chemical Biology (1)
- Nature Communications (7)
- Nature Metabolism (2)
- Oncogene (1)
- Parasitology (1)
- PLOS Biology (1)
- PLOS Pathogens (4)
- Proceedings of the National Academy of Sciences of the United States of America (2)
- Science (2)
- Science advances (1)
- Science of the Total Environment (1)
- The Lancet (3)
- Trends in Parasitology (1)
- Wellcome Open Research (1)