James Macrae
STP Lead
James completed a PhD on structural glycobiology in trypanosomatid parasites at the University of Dundee, before moving to the University of Melbourne in 2006.
Here, he expanded these interests into developing novel techniques in order to study the metabolism of apicomplexan parasites, including Toxoplasma gondii and the malaria parasite Plasmodium falciparum. This mass spectrometry-based metabolism research has now grown into a field in its own right – metabolomics.
Since 2013 James has been of Head of Metabolomics at the Francis Crick Institute, where he develops new tools for metabolomics research in a number of areas (e.g. cancer metabolism, heart disease, mitochondrial dysfunction), while maintaining interests in host-parasite metabolism.
Qualifications and history
Research topics
- Biochemistry & Proteomics (29)
- Cell Biology (30)
- Cell Cycle & Chromosomes (15)
- (-)Chemical Biology & High Throughput (30)
- Computational & Systems Biology (30)
- Developmental Biology (29)
- Gene Expression (9)
- Genetics & Genomics (23)
- Genome Integrity & Repair (21)
- Human Biology & Physiology (29)
- Imaging (11)
- Immunology (28)
- Infectious Disease (28)
- Metabolism (29)
- Microfabrication & Bioengineering (3)
- Model Organisms (25)
- Neurosciences (15)
- Signalling & Oncogenes (29)
- Stem Cells (18)
- Structural Biology & Biophysics (19)
- Synthetic Biology (6)
- Tumour Biology (30)
Publication type
Journal
- British Journal of Cancer (1)
- Cancer Cell (2)
- Cell Reports Medicine (1)
- FEBS Journal (1)
- Immunity (1)
- Journal of Biological Chemistry (1)
- Journal of Clinical Investigation (1)
- Molecular Systems Biology (1)
- Nature Biotechnology (2)
- Nature Cancer (3)
- Nature Cell Biology (1)
- Nature Chemical Biology (1)
- Nature Communications (5)
- Nature Metabolism (1)
- Oncogene (1)
- PLOS Pathogens (1)
- Science (1)
- Science advances (1)
- The Lancet (3)
- Wellcome Open Research (1)