Jamie Mitchell

VISITING SCIENTIST

Human stem cell derived spinal motor neurons.

Patani lab

Human Stem Cells and Neurodegeneration Laboratory

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Displaying 1 - 8 of 8

Last updated : 27 May 2022 03:50

MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration

Authors (34)

Roberto Simone
Faiza Javad
Warren Emmett
Oscar Wilkins
Filipa Lourenço Almeida
Natalia Barahona-Torres
[...]
Per Svenningsson
Thomas T Warner
Vincent Plagnol
Jernej Ule
Rohan de Silva

Nature

Published 3 June 2021

Crick labs

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A non-toxic concentration of telomerase inhibitor BIBR1532 fails to reduce TERT expression in a feeder-free induced pluripotent stem cell model of human motor neurogenesis

Authors (4)

International Journal of Molecular Sciences

Published 23 March 2021

Crick labs

Rickie Patani

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Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis

Authors (10)

Phillip Smethurst
Emmanuel Risse
Giulia Tyzack
Jamie Mitchell
Doaa Taha
Yun-Ru Chen
Jia Newcombe
John Collinge
Katie Sidle
Rickie Patani

Brain

Published 10 February 2020

Crick labs

Rickie Patani

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Delineating astrocytic cytokine responses in a human stem cell model of neural trauma

Authors (12)

Eric Peter Thelin
Claire E Hall
Giulia Tyzack
Arvid Frostell
Susan Giorgi-Coll
Aftab Alam
[...]
Jamie Mitchell
Tamara Tajsic
Peter J Hutchinson
Rickie Patani
Adel Helmy

Journal of Neurotrauma

Published 1 January 2020

Crick labs

Rickie Patani

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Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis

Authors (12)

Brain

Published 1 September 2019

Crick labs

Full details

Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS

Authors (13)

Raphaelle Luisier
Giulia Tyzack
Claire E Hall
Jamie Mitchell
Helen Devine
Doaa Taha
[...]
Linda Greensmith
Jia Newcombe
Jernej Ule
Nicholas Luscombe
Rickie Patani

Nature Communications

Published 22 May 2018

Crick labs

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Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering

Authors (22)

Sara Martina Maffioletti
Shilpita Sarcar
Alexander BH Henderson
Ingra Mannhardt
Luca Pinton
Louise Anne Moyle
[...]
Rickie Patani
Peter S Zammit
Dominic J Wells
Thomas Eschenhagen
Francesco Saverio Tedesco

Cell Reports

Published 17 April 2018

Crick labs

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G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

Authors (33)

Roberto Simone
Rubika Balendra
Thomas G Moens
Elisavet Preza
Katherine M Wilson
Amanda Heslegrave
[...]
Gary Parkinson
Stephen Neidle
Rickie Patani
Pietro Fratta
Adrian M Isaacs

EMBO Molecular Medicine

Published 1 January 2018

Crick labs

Rickie Patani

Full details

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Coronavirus (COVID-19) research

About us

Jamie Mitchell

VISITING SCIENTIST

Patani lab

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Crick Pre-Crick

MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration

A non-toxic concentration of telomerase inhibitor BIBR1532 fails to reduce TERT expression in a feeder-free induced pluripotent stem cell model of human motor neurogenesis

Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis

Delineating astrocytic cytokine responses in a human stem cell model of neural trauma

Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis

Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS

Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering

G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

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