John Mccauley

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase

Authors (19)

Biochemical Journal

Published 16 July 2021

Crick labs/ facilities

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Diversity in the circulation of influenza A(H3N2) viruses in the northern hemisphere in the 2018-19 season

Authors (13)

Rakefet Pando
Shahar Stern
Ital Nemet
Aharona Glatman-Freedman
Hanna Sefty
Neta S Zuckerman
[...]
John Mccauley
Lital Keinan-Boker
Ella Mendelson
Rodney S Daniels
Michal Mandelboim

Vaccines (Basel)

Published 13 April 2021

Crick labs/ facilities

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Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans

Authors (23)

Barbara Holzer
Pramila Rijal
Adam McNee
Basudev Paudyal
Veronica Martini
Becky Clark
[...]
John Mccauley
Rodney S Daniels
John A Hammond
Alain R Townsend
Elma Tchilian

PLOS Pathogens

Published 4 March 2021

Crick labs/ facilities

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Breadth and function of antibody response to acute SARS-CoV-2 infection in humans

Authors (25)

Kuan-Ying A Huang
Tiong Kit Tan
Ting-Hua Chen
Chung-Guei Huang
Ruth Harvey
Saira Hussain
[...]
William James
Rodney S Daniels
John Mccauley
Pramila Rijal
Alain R Townsend

PLOS Pathogens

Published 26 February 2021

Crick labs/ facilities

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A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

Authors (54)

Tiong Kit Tan
Pramila Rijal
Rolle Rahikainen
Anthony H Keeble
Lisa Schimanski
Saira Hussain
[...]
John Mccauley
David I Stuart
Kuan-Ying A Huang
Mark Howarth
Alain R Townsend

Nature Communications

Published 22 January 2021

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Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

Authors (47)

Kevin Ng
Nikhil Faulkner
Georgina H Cornish
Annachiara Rosa
Ruth Harvey
Saira Hussain
[...]
Steve Gamblin
Laura E Mccoy
Peter Cherepanov
Eleni Nastouli
George Kassiotis

Science

Published 11 December 2020

Crick labs/ facilities

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2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

Authors (229)

Jens H Kuhn
Scott Adkins
Daniela Alioto
Sergey V Alkhovsky
Gaya K Amarasinghe
Simon J Anthony
[...]
F Murilo Zerbini
Tong Zhang
Yong-Zhen Zhang
Guohui Zhou
Xueping Zhou

Archives of Virology

Published 1 December 2020

Crick labs/ facilities

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Integrating genotypes and phenotypes improves long-term forecasts of seasonal influenza A/H3N2 evolution

Authors (20)

John Huddleston
John R Barnes
Thomas Rowe
Xiyan Xu
Rebecca Kondor
David E Wentworth
[...]
Ian Barr
Kanta Subbarao
Pierre Barrat-Charlaix
Richard A Neher
Trevor Bedford

eLife

Published 2 September 2020

Crick labs/ facilities

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Molecular characterization of Influenza C viruses from outbreaks in Hong Kong SAR, China

Authors (12)

Rodney S Daniels
Herman Tse
Burcu Ermetal
Zheng Xiang
Deb Jackson
Jeremy Guntoro
[...]
Aengus Stewart
Karen J Cross
Saira Hussain
John Mccauley
Janice Lo

Journal of Virology

Published 1 November 2020

Crick labs/ facilities

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Genetic diversity of influenza A viruses circulating in Bulgaria during the 2018-2019 winter season

Authors (9)

Neli Korsun
Rodney Daniels
Svetla Angelova
Burcu Ermetal
Iliyana Grigorova
Silvia Voleva
Ivelina Trifonova
Anna Kurchatova
John Mccauley

Journal of Medical Microbiology

Published 1 July 2020

Crick labs/ facilities

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Pandemic potential of highly pathogenic avian influenza clade 2.3.4.4 A(H5) viruses

Authors (12)

Reina Yamaji
Magdi D Saad
Charles T Davis
David E Swayne
Dayan Wang
Frank YK Wong
[...]
JS Malik Peiris
Richard J Webby
Ron AM Fouchier
Yoshihiro Kawaoka
Wenqing Zhang

Reviews in Medical Virology

Published 1 May 2020

Crick labs/ facilities

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Broadly inhibiting antineuraminidase monoclonal antibodies induced by trivalent influenza vaccine and H7N9 infection in humans

Authors (10)

Pramila Rijal
Bei Bei Wang
Tiong Kit Tan
Lisa Schimanski
Philipp Janesch
Tao Dong
John Mccauley
Rodney S Daniels
Alain R Townsend
Kuan-Ying A Huang

Journal of Virology

Published 31 January 2020

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Segment 2 from influenza A(H1N1) 2009 pandemic viruses confers temperature-sensitive haemagglutinin yield on candidate vaccine virus growth in eggs that can be epistatically complemented by PB2 701D

Authors (6)

Saira Hussain
Matthew L Turnbull
Rute M Pinto
John Mccauley
Othmar G Engelhardt
Paul Digard

Journal of General Virology

Published 1 July 2019

Crick labs/ facilities

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Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses

Authors (22)

Haixia Xiao
Tianling Guo
Mi Yang
Jianxun Qi
Chaobin Huang
Yuanyuan Hong
[...]
Jinghua Yan
Liling Chen
Yi Shi
Weizhi Chen
George Fu Gao

Cell Discovery

Published 16 April 2019

Crick labs/ facilities

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Detection of influenza C virus infection among hospitalized patients, Cameroon

Authors (7)

Richard Njouom
Gwladys Chavely Monamele
Burcu Ermetal
Serge Tchatchouang
Sylvie Moyo-Tetang
John Mccauley
Rodney S Daniels

Emerging Infectious Diseases

Published 1 March 2019

Crick labs/ facilities

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Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion

Authors (11)

Thomas P Peacock
Donald Benton
Jean-Remy Sadeyen
Pengxiang Chang
Joshua E Sealy
Juliet E Bryant
Stephen R Martin
Holly Shelton
John Mccauley
Wendy S Barclay
Munir Iqbal

Emerging Microbes & Infections

Published 15 January 2019

Crick labs/ facilities

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Association of increased receptor-binding avidity of influenza A(H9N2) viruses with escape from antibody-based immunity and enhanced zoonotic potential

Authors (13)

Joshua E Sealy
Tahir Yaqub
Thomas P Peacock
Pengxiang Chang
Burcu Ermetal
Anabel Clements
[...]
Holly Shelton
Juliet E Bryant
Rod S Daniels
John Mccauley
Munir Iqbal

Emerging Infectious Diseases

Published 1 January 2019

Crick labs/ facilities

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Cell culture-derived influenza vaccines in the severe 2017-2018 epidemic season: a step towards improved influenza vaccine effectiveness

Authors (8)

Ian G Barr
Ruben O Donis
Jacqueline M Katz
John Mccauley
Takato Odagiri
Heidi Trusheim
Theodore F Tsai
David E Wentworth

NPJ Vaccines

Published 9 October 2018

Crick labs/ facilities

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Overview of three influenza seasons in Georgia, 2014-2017

Authors (12)

Ann Machablishvili
Giorgi Chakhunashvili
Khatuna Zakhashvili
Irakli Karseladze
Olgha Tarkhan-Mouravi
Mari Gavashelidze
[...]
Lela Sabadze
Paata Imnadze
Rodney S Daniels
Burcu Ermetal
John Mccauley

PLOS ONE

Published 27 July 2018

Crick labs/ facilities

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Antigenic and genetic characterization of influenza viruses isolated in Mozambique during the 2015 season

Authors (15)

Almiro Tivane
Rodney Daniels
Neuza Nguenha
Loira Machalele
Afonso Nacoto
Mirela Pale
[...]
Judite Salência
Félix Albati
Eduardo Gudo
Tufária Mussá
John Mccauley

PLOS ONE

Published 26 July 2018

Crick labs/ facilities

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Coronavirus (COVID-19) response

Vacancies

A drop of hope

Coronavirus (COVID-19) research

About us

John Mccauley

DIRECTOR-WORLD INFLUENZA CENTRE

Influenza lab

Year published

Research topics

Publication type

Journal

Crick Pre-Crick

Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase

Diversity in the circulation of influenza A(H3N2) viruses in the northern hemisphere in the 2018-19 season

Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans

Breadth and function of antibody response to acute SARS-CoV-2 infection in humans

A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

Integrating genotypes and phenotypes improves long-term forecasts of seasonal influenza A/H3N2 evolution

Molecular characterization of Influenza C viruses from outbreaks in Hong Kong SAR, China

Genetic diversity of influenza A viruses circulating in Bulgaria during the 2018-2019 winter season

Pandemic potential of highly pathogenic avian influenza clade 2.3.4.4 A(H5) viruses

Broadly inhibiting antineuraminidase monoclonal antibodies induced by trivalent influenza vaccine and H7N9 infection in humans

Segment 2 from influenza A(H1N1) 2009 pandemic viruses confers temperature-sensitive haemagglutinin yield on candidate vaccine virus growth in eggs that can be epistatically complemented by PB2 701D

Light chain modulates heavy chain conformation to change protection profile of monoclonal antibodies against influenza A viruses

Detection of influenza C virus infection among hospitalized patients, Cameroon

Variability in H9N2 haemagglutinin receptor-binding preference and the pH of fusion

Association of increased receptor-binding avidity of influenza A(H9N2) viruses with escape from antibody-based immunity and enhanced zoonotic potential

Cell culture-derived influenza vaccines in the severe 2017-2018 epidemic season: a step towards improved influenza vaccine effectiveness

Overview of three influenza seasons in Georgia, 2014-2017

Antigenic and genetic characterization of influenza viruses isolated in Mozambique during the 2015 season

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