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Breadcrumb Research A Z researchers Jonas Demeulemeester VISITING SCIENTIST Van Loo lab Cancer Genomics Laboratory Year published2022 (2)2021 (3)2020 (9)2019 (1)2018 (1)2017 (1)2016 (1) Facet Year publishedResearch topicsChemical Biology & High Throughput (4)Computational & Systems Biology (18)Gene Expression (1)Genetics & Genomics (18)Genome Integrity & Repair (4)Human Biology & Physiology (18)Signalling & Oncogenes (4)Structural Biology & Biophysics (6)Tumour Biology (18) Facet Research topicsPublication typeJournal article (18)Primary research (18) Facet Publication typeJournalCell (1)Genome Biology (1)Journal of Pathology (1)Nature (2)Nature Biotechnology (2)Nature Communications (9)Nature Genetics (2) Facet JournalCrick Pre-CrickCrick publications (18) Facet Crick Pre-Crick Displaying 1 - 18 of 18Last updated : 31 March 2023 03:58 Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression Authors (40) Shaolong Cao Jennifer R Wang Shuangxi Ji Peng Yang Yaoyi Dai Shuai Guo[...] Hongtu Zhu Alfonso UrbanucciJonas DemeulemeesterPeter Van Loo Wenyi Wang Nature Biotechnology Published 1 November 2022 Crick labsPeter Van LooCharles SwantonFull details Biallelic mutations in cancer genomes reveal local mutational determinants Authors (4)Jonas Demeulemeester Stefan C Dentro Moritz GerstungPeter Van Loo Nature Genetics Published 1 February 2022 Crick labsPeter Van LooFull details Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture Authors (43) Eva G ÁlvarezJonas Demeulemeester Paula OteroClemency Jolly Daniel García-Souto Ana Pequeño-Valtierra[...] Urtzi Garaigorta Peter J Campbell Hidewaki NakagawaPeter Van Loo Jose MC Tubio Nature Communications Published 25 November 2021 Crick labsPeter Van LooFull details A pan-cancer landscape of somatic mutations in non-unique regions of the human genome Authors (6)Maxime TarabichiJonas DemeulemeesterAnnelien Verfaillie Adrienne M FlanaganPeter Van Loo Tomasz Konopka Nature Biotechnology Published 1 December 2021 Crick labs/ facilitiesPeter Van LooScientific computingFull details Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes Authors (121) Stefan C Dentro Ignaty Leshchiner Kerstin HaaseMaxime Tarabichi Jeff Wintersinger Amit G Deshwar[...] Paul T Spellman David C Wedge Peter Van Loo PCAWG Evolution and Heterogeneity Working Group PCAWG Consortium Cell Published 15 April 2021 Crick labs/ facilitiesPeter Van LooCharles SwantonScientific computingFull details Pervasive chromosomal instability and karyotype order in tumour evolution Authors (55)Tom WatkinsEmilia Lim Marina Petkovic Sergi ElizaldeNicolai BirkbakGareth Wilson[...]Peter Van Loo Samuel F Bakhoum Roland F Schwarz Nicholas McGranahanCharles Swanton Nature Published 5 November 2020 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonNicholas LuscombeBioinformatics and BiostatisticsScientific computingFull details Drivers underpinning the malignant transformation of giant cell tumour of bone Authors (21)Matthew Fittall Iben Lyskjaer Peter Ellery Patrick Lombard Jannat Ijaz Anna-Christina Strobl[...] David TW Jones Nischalan PillayPeter Van Loo Sam Behjati Adrienne M Flanagan Journal of Pathology Published 1 December 2020 Crick labsPeter Van LooFull details A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns Authors (1385) Wei Jiao Gurnit Atwal Paz Polak Rosa Karlic Edwin Cuppen Fatima Al-Shahrour[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details Combined burden and functional impact tests for cancer driver discovery using DriverPower Authors (1455) Shimin Shuai Federico Abascal Samirkumar B Amin Gary D Bader Pratiti Bandopadhayay Jonathan Barenboim[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details Divergent mutational processes distinguish hypoxic and normoxic tumours Authors (1328) Vinayak Bhandari Constance H Li Robert G Bristow Paul C Boutros Lauri A Aaltonen Federico Abascal[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details Genomic footprints of activated telomere maintenance mechanisms in cancer Authors (1413) Lina Sieverling Chen Hong Sandra D Koser Philip Ginsbach Kortine Kleinheinz Barbara Hutter[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details Integrative pathway enrichment analysis of multivariate omics data Authors (1459) Marta Paczkowska Jonathan Barenboim Nardnisa Sintupisut Natalie S Fox Helen Zhu Diala Abd-Rabbo[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition Authors (53) Bernardo Rodriguez-Martin Eva G Alvarez Adrian Baez-Ortega Jorge Zamora Fran SupekJonas Demeulemeester[...] Kathleen H Burns PCAWG Structural Variation Working Group Peter J Campbell Jose MC Tubio PCAWG Consortium Nature Genetics Published 1 March 2020 Crick labsPeter Van LooFull details Pathway and network analysis of more than 2500 whole cancer genomes Authors (1453) Matthew A Reyna David Haan Marta Paczkowska Lieven PC Verbeke Miguel Vazquez Abdullah Kahraman[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details Neoantigen-directed immune escape in lung cancer evolution Authors (29)Rachel RosenthalElizabeth Larose Cadieux Roberto SalgadoMaise Al Bakir David A MooreCrispin Hiley[...]Peter Van Loo Stephan Beck Nicholas McGranahanCharles Swanton The TRACERx Consortium Nature Published 20 March 2019 Crick labs/ facilitiesPeter Van LooCharles SwantonExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Recurrent rearrangements of FOS and FOSB define osteoblastoma Authors (22)Matthew Fittall William Mifsud Nischalan Pillay Hongtao Ye Anna-Christina StroblAnnelien Verfaillie[...]Peter Van Loo Cristina R Antonescu Peter J Campbell Adrienne M Flanagan Sam Behjati Nature Communications Published 1 June 2018 Crick labsPeter Van LooFull details Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors Authors (18) Jiqiu ChengJonas Demeulemeester David C Wedge Hans Kristian Vollan Jason J Pitt Hege G Russnes[...] Vessela N Kristensen Michael R Stratton Ole Christian Lingjærde Yves MoreauPeter Van Loo Nature Communications Published 31 October 2017 Crick labsPeter Van LooFull details Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing Authors (20)Jonas Demeulemeester Parveen Kumar Elen K Møller Silje Nord David C Wedge April Peterson[...] Kevin P White Vessela N KristensenPeter Van Loo Thierry Voet Bjørn Naume Genome Biology Published 9 December 2016 Crick labsPeter Van LooFull details
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression Authors (40) Shaolong Cao Jennifer R Wang Shuangxi Ji Peng Yang Yaoyi Dai Shuai Guo[...] Hongtu Zhu Alfonso UrbanucciJonas DemeulemeesterPeter Van Loo Wenyi Wang Nature Biotechnology Published 1 November 2022 Crick labsPeter Van LooCharles SwantonFull details
Biallelic mutations in cancer genomes reveal local mutational determinants Authors (4)Jonas Demeulemeester Stefan C Dentro Moritz GerstungPeter Van Loo Nature Genetics Published 1 February 2022 Crick labsPeter Van LooFull details
Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture Authors (43) Eva G ÁlvarezJonas Demeulemeester Paula OteroClemency Jolly Daniel García-Souto Ana Pequeño-Valtierra[...] Urtzi Garaigorta Peter J Campbell Hidewaki NakagawaPeter Van Loo Jose MC Tubio Nature Communications Published 25 November 2021 Crick labsPeter Van LooFull details
A pan-cancer landscape of somatic mutations in non-unique regions of the human genome Authors (6)Maxime TarabichiJonas DemeulemeesterAnnelien Verfaillie Adrienne M FlanaganPeter Van Loo Tomasz Konopka Nature Biotechnology Published 1 December 2021 Crick labs/ facilitiesPeter Van LooScientific computingFull details
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes Authors (121) Stefan C Dentro Ignaty Leshchiner Kerstin HaaseMaxime Tarabichi Jeff Wintersinger Amit G Deshwar[...] Paul T Spellman David C Wedge Peter Van Loo PCAWG Evolution and Heterogeneity Working Group PCAWG Consortium Cell Published 15 April 2021 Crick labs/ facilitiesPeter Van LooCharles SwantonScientific computingFull details
Pervasive chromosomal instability and karyotype order in tumour evolution Authors (55)Tom WatkinsEmilia Lim Marina Petkovic Sergi ElizaldeNicolai BirkbakGareth Wilson[...]Peter Van Loo Samuel F Bakhoum Roland F Schwarz Nicholas McGranahanCharles Swanton Nature Published 5 November 2020 Crick labs/ facilitiesPeter Van LooSamra TurajlicCharles SwantonNicholas LuscombeBioinformatics and BiostatisticsScientific computingFull details
Drivers underpinning the malignant transformation of giant cell tumour of bone Authors (21)Matthew Fittall Iben Lyskjaer Peter Ellery Patrick Lombard Jannat Ijaz Anna-Christina Strobl[...] David TW Jones Nischalan PillayPeter Van Loo Sam Behjati Adrienne M Flanagan Journal of Pathology Published 1 December 2020 Crick labsPeter Van LooFull details
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns Authors (1385) Wei Jiao Gurnit Atwal Paz Polak Rosa Karlic Edwin Cuppen Fatima Al-Shahrour[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details
Combined burden and functional impact tests for cancer driver discovery using DriverPower Authors (1455) Shimin Shuai Federico Abascal Samirkumar B Amin Gary D Bader Pratiti Bandopadhayay Jonathan Barenboim[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details
Divergent mutational processes distinguish hypoxic and normoxic tumours Authors (1328) Vinayak Bhandari Constance H Li Robert G Bristow Paul C Boutros Lauri A Aaltonen Federico Abascal[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details
Genomic footprints of activated telomere maintenance mechanisms in cancer Authors (1413) Lina Sieverling Chen Hong Sandra D Koser Philip Ginsbach Kortine Kleinheinz Barbara Hutter[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details
Integrative pathway enrichment analysis of multivariate omics data Authors (1459) Marta Paczkowska Jonathan Barenboim Nardnisa Sintupisut Natalie S Fox Helen Zhu Diala Abd-Rabbo[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition Authors (53) Bernardo Rodriguez-Martin Eva G Alvarez Adrian Baez-Ortega Jorge Zamora Fran SupekJonas Demeulemeester[...] Kathleen H Burns PCAWG Structural Variation Working Group Peter J Campbell Jose MC Tubio PCAWG Consortium Nature Genetics Published 1 March 2020 Crick labsPeter Van LooFull details
Pathway and network analysis of more than 2500 whole cancer genomes Authors (1453) Matthew A Reyna David Haan Marta Paczkowska Lieven PC Verbeke Miguel Vazquez Abdullah Kahraman[...] Nicholas van As Carolien HM van Deurzen Marc J van de Vijver L van’t Veer Christian von Mering Nature Communications Published 5 February 2020 Crick labsPeter Van LooDavid JonesFull details
Neoantigen-directed immune escape in lung cancer evolution Authors (29)Rachel RosenthalElizabeth Larose Cadieux Roberto SalgadoMaise Al Bakir David A MooreCrispin Hiley[...]Peter Van Loo Stephan Beck Nicholas McGranahanCharles Swanton The TRACERx Consortium Nature Published 20 March 2019 Crick labs/ facilitiesPeter Van LooCharles SwantonExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Recurrent rearrangements of FOS and FOSB define osteoblastoma Authors (22)Matthew Fittall William Mifsud Nischalan Pillay Hongtao Ye Anna-Christina StroblAnnelien Verfaillie[...]Peter Van Loo Cristina R Antonescu Peter J Campbell Adrienne M Flanagan Sam Behjati Nature Communications Published 1 June 2018 Crick labsPeter Van LooFull details
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors Authors (18) Jiqiu ChengJonas Demeulemeester David C Wedge Hans Kristian Vollan Jason J Pitt Hege G Russnes[...] Vessela N Kristensen Michael R Stratton Ole Christian Lingjærde Yves MoreauPeter Van Loo Nature Communications Published 31 October 2017 Crick labsPeter Van LooFull details
Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing Authors (20)Jonas Demeulemeester Parveen Kumar Elen K Møller Silje Nord David C Wedge April Peterson[...] Kevin P White Vessela N KristensenPeter Van Loo Thierry Voet Bjørn Naume Genome Biology Published 9 December 2016 Crick labsPeter Van LooFull details
