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Breadcrumb Research A-Z researchers Kelvin Dempster Affiliated Researcher Ultanir lab Kinases and Brain Development Laboratory Year published 2026 (1) 2024 (2) 2023 (2) Facet Year published Research topics Cell Biology (2) Chemical Biology & High Throughput (2) Developmental Biology (2) Neurosciences (4) Signalling & Oncogenes (2) Facet Research topics Crick Pre-Crick Crick publications (5) Facet Crick Pre-Crick Publication type Dataset (1) Journal article (3) Preprint (1) Primary research (3) Facet Publication type Journal ACS Chemical Neuroscience (1) BioRxiv (1) eLife (1) Molecular Psychiatry (2) Facet Journal Displaying 1 - 5 of 5Last updated : 19 August 2026 02:46 CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development Preprint Authors (21) Simeon Mihaylov Andre Teixeira Lopes Margaux Silvestre Gaia Bianchini Helen R Flynn Almaz Huseynova [...] Marcel Köhn Mark Skehel Jernej Ule Florencia Iacaruso Sila Ultanir bioRxiv Published 7 April 2026 Crick labs/ facilities Sila Ultanir Jernej Ule | Ben Blencowe Flor Iacaruso Proteomics Bioinformatics and Biostatistics Structural Biology Genetic Modification Service Biological Research Facility Full details Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain Authors (5) Margaux Silvestre Kelvin Dempster Simeon Mihaylov Suzanne Claxton Sila Ultanir Molecular Psychiatry Published 1 June 2024 Crick labs/ facilities Sila Ultanir Genetic Modification Service Biological Research Facility Full details Data associated with "Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain" Authors (5) Margaux Silvestre Kelvin Dempster Simeon Mihaylov Suzanne Claxton Sila Ultanir Figshare Published 15 January 2024 Crick labs/ facilities Sila Ultanir Genetic Modification Service Biological Research Facility Full details Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology Authors (19) Anna Castano Margaux Silvestre Carrow I Wells Jennifer L Sanderson Carla A Ferrer Han Wee Ong [...] Navlot S Pabla Alex N Bullock Tim A Benke Sila Ultanir Alison D Axtman eLife Published 25 July 2023 Crick labs Sila Ultanir Full details Discovery of a potent and selective CDKL5/GSK3 chemical probe that is neuroprotective Authors (16) Han Wee Ong Yi Liang William Richardson Emily R Lowry Carrow I Wells Xiangrong Chen [...] Navjot S Pabla Sila Ultanir Alex N Bullock David H Drewry Alison D Axtman ACS Chemical Neuroscience Published 3 May 2023 Crick labs Sila Ultanir Full details
CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development Preprint Authors (21) Simeon Mihaylov Andre Teixeira Lopes Margaux Silvestre Gaia Bianchini Helen R Flynn Almaz Huseynova [...] Marcel Köhn Mark Skehel Jernej Ule Florencia Iacaruso Sila Ultanir bioRxiv Published 7 April 2026 Crick labs/ facilities Sila Ultanir Jernej Ule | Ben Blencowe Flor Iacaruso Proteomics Bioinformatics and Biostatistics Structural Biology Genetic Modification Service Biological Research Facility Full details
Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain Authors (5) Margaux Silvestre Kelvin Dempster Simeon Mihaylov Suzanne Claxton Sila Ultanir Molecular Psychiatry Published 1 June 2024 Crick labs/ facilities Sila Ultanir Genetic Modification Service Biological Research Facility Full details
Data associated with "Cell type-specific expression, regulation and compensation of CDKL5 activity in mouse brain" Authors (5) Margaux Silvestre Kelvin Dempster Simeon Mihaylov Suzanne Claxton Sila Ultanir Figshare Published 15 January 2024 Crick labs/ facilities Sila Ultanir Genetic Modification Service Biological Research Facility Full details
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology Authors (19) Anna Castano Margaux Silvestre Carrow I Wells Jennifer L Sanderson Carla A Ferrer Han Wee Ong [...] Navlot S Pabla Alex N Bullock Tim A Benke Sila Ultanir Alison D Axtman eLife Published 25 July 2023 Crick labs Sila Ultanir Full details
Discovery of a potent and selective CDKL5/GSK3 chemical probe that is neuroprotective Authors (16) Han Wee Ong Yi Liang William Richardson Emily R Lowry Carrow I Wells Xiangrong Chen [...] Navjot S Pabla Sila Ultanir Alex N Bullock David H Drewry Alison D Axtman ACS Chemical Neuroscience Published 3 May 2023 Crick labs Sila Ultanir Full details
