Kevin Rouault-Pierre

Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia

Authors (11)

Alexander Waclawiczek
Ashley Hamilton
Kevin Rouault-Pierre
Ander Abarrategi
Manuel Garcia Albornoz
Farideh Miraki-Moud
Nourdine Bah
John Gribben
Jude Fitzgibbon
David Taussig
Dominique Bonnet

Journal of Clinical Investigation

Published 1 June 2020

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Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment

Authors (19)

Aurélie Caye
Kevin Rouault-Pierre
Marion Strullu
Elodie Lainey
Ander Abarrategi
Odile Fenneteau
[...]
Jean-Hugues Dalle
André Baruchel
Christine Chomienne
Hélène Cavé
Dominique Bonnet

Leukemia

Published 1 June 2020

Crick labs/ facilities

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The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia

Authors (9)

Alessandro Di Tullio
Kevin Rouault-Pierre
Ander Abarrategi
Syed Mian
William Grey
John Gribben
Aengus Stewart
Elizabeth Blackwood
Dominique Bonnet

Nature Communications

Published 22 November 2017

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Increased vascular permeability in the bone marrow microenvironment contributes to disease progression and drug response in acute myeloid leukemia

Authors (13)

Diana Passaro
Alessandro Di Tullio
Ander Abarrategi
Kevin Rouault-Pierre
Katie Foster
Linda Ariza-McNaughton
[...]
Leena Bhaw
Giovanni Diana
François Lassailly
John Gribben
Dominique Bonnet

Cancer Cell

Published 11 September 2017

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Adaptive from innate: Human IFN-γ+CD4+ T cells can arise directly from CXCL8-producing recent thymic emigrants in babies and adults

Authors (10)

Abhishek Das
Kevin Rouault-Pierre
Shraddha Kamdar
Iria Gomez-Tourino
Kristie Wood
Ian Donaldson
Charles A Mein
Dominique Bonnet
Adrian Hayday
Deena L Gibbons

Journal of Immunology

Published 1 September 2017

Crick labs

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Nuclear factor erythroid 2 regulates human HSC self-renewal and T cell differentiation by preventing NOTCH1 activation

Authors (5)

Stem Cell Reports

Published 11 July 2017

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Preclinical modeling of myelodysplastic syndromes

Authors (16)

Kevin Rouault-Pierre
Syed Mian
M Goulard
A Abarrategi
A Di Tulio
AE Smith
[...]
C Chomienne
P Fenaux
C Dosquet
GJ Mufti
Dominique Bonnet

Leukemia

Published 1 December 2017

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Myelodysplastic syndrome can propagate from the multipotent progenitor compartment

Authors (7)

Kevin Rouault-Pierre
Alexander E Smith
Syed Mian
Irene Pizzitola
Austin G Kulasekararaj
Ghulam J Mufti
Dominique Bonnet

Haematologica

Published 1 January 2017

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SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment

Authors (9)

Syed A Mian
Kevin Rouault-Pierre
Alexander E Smith
Thomas Seidl
Irene Pizzitola
Aytug Kizilors
Austin G Kulasekararaj
Dominique Bonnet
Ghulam J Mufti

Nature Communications

Published 8 December 2015

Crick labs/ facilities

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Different motile behaviors of human hematopoietic stem versus progenitor cells at the osteoblastic niche

Authors (6)

Katie Foster
François Lassailly
Fernando Dos Anjos Afonso
Erin Currie
Kevin Rouault-Pierre
Dominique Bonnet

Stem Cell Reports

Published 10 November 2015

Crick labs/ facilities

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Kevin Rouault-Pierre

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Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia

Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment

The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia

Increased vascular permeability in the bone marrow microenvironment contributes to disease progression and drug response in acute myeloid leukemia

Adaptive from innate: Human IFN-γ+CD4+ T cells can arise directly from CXCL8-producing recent thymic emigrants in babies and adults

Nuclear factor erythroid 2 regulates human HSC self-renewal and T cell differentiation by preventing NOTCH1 activation

Preclinical modeling of myelodysplastic syndromes

Myelodysplastic syndrome can propagate from the multipotent progenitor compartment

SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment

Different motile behaviors of human hematopoietic stem versus progenitor cells at the osteoblastic niche

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