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Breadcrumb Research A Z researchers Laure Botella SENIOR LABORATORY RESEARCH SCIENTIST Email Address: Email Year published2023 (4)2022 (1)2021 (1)2019 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (1)Cell Biology (6)Computational & Systems Biology (1)Genetics & Genomics (1)Infectious Disease (7)Metabolism (1)Model Organisms (6)Structural Biology & Biophysics (1) Facet Research topicsPublication typeJournal article (7)Primary research (7) Facet Publication typeJournalFEBS Open Bio (1)Journal of Clinical Investigation (1)mBio (1)Molecular Cell (1)Nature Microbiology (1)PLOS Pathogens (1)The Journal of Cell Biology (1) Facet JournalCrick Pre-CrickCrick publications (7) Facet Crick Pre-Crick Displaying 1 - 7 of 7Last updated : 10 December 2023 02:39 Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages Authors (9)Enrica PellegrinoBeren AylanClaudio BussiTony FearnsElliott BernardNatalia AthanasiadiPierre SantucciLaure BotellaMaximiliano Gutierrez The Journal of Cell Biology Published 4 December 2023 Crick labs/ facilitiesMaximiliano GutierrezLight MicroscopyHuman Embryonic Stem CellFull details ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages Authors (9)Beren AylanElliott BernardEnrica PellegrinoLaure BotellaTony FearnsNatalia AthanasiadiClaudio BussiPierre SantucciMaximiliano Gutierrez Nature Microbiology Published 1 May 2023 Crick labs/ facilitiesMaximiliano GutierrezLight MicroscopyHuman Embryonic Stem CellElectron MicroscopyFull details A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages Authors (23) Melissa Bedard Sanne van der NietElliott Bernard Gregory Babunovic Tan-Yun ChengBeren Aylan[...] Joseph Keane Sho YamasakiMaximiliano Gutierrez Nicole van der Wel D Branch Moody Journal of Clinical Investigation Published 15 March 2023 Crick labsMaximiliano GutierrezFull details High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages Authors (4)Beren AylanLaure BotellaMaximiliano GutierrezPierre Santucci FEBS Open Bio Published 1 July 2023 Crick labs/ facilitiesMaximiliano GutierrezLight MicroscopyFull details Visualizing pyrazinamide action by live single-cell imaging of phagosome acidification and Mycobacterium tuberculosis pH homeostasis Authors (8)Pierre SantucciBeren AylanLaure BotellaElliott BernardClaudio BussiEnrica PellegrinoNatalia AthanasiadiMaximiliano Gutierrez mBio Published 1 April 2022 Crick labsMaximiliano GutierrezFull details Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation Authors (15)Christophe QuevalTony FearnsLaure Botella Alicia Smyth Laura Schnettger Morgane Mitermite[...] Matthias Trost Dirk Werling Francisco J Salguero Stephen V GordonMaximiliano Gutierrez PLOS Pathogens Published 15 March 2021 Crick labs/ facilitiesMaximiliano GutierrezLight MicroscopyElectron MicroscopyFull details An NAD+ phosphorylase toxin triggers Mycobacterium tuberculosis cell death Authors (23) Diana Mendes Freire Claude GutierrezAcely Garza-Garcia Anna D Grabowska Ambre J Sala Kanchiyaphat Ariyachaokun[...] Pierre GenevauxLuiz Pedro Carvalho Matthias Wilmanns Annabel HA Parret Olivier Neyrolles Molecular Cell Published 18 February 2019 Crick labs/ facilitiesLuiz Pedro CarvalhoMRC Biomedical NMR CentreFull details
Peroxisomal ROS control cytosolic Mycobacterium tuberculosis replication in human macrophages Authors (9)Enrica PellegrinoBeren AylanClaudio BussiTony FearnsElliott BernardNatalia AthanasiadiPierre SantucciLaure BotellaMaximiliano Gutierrez The Journal of Cell Biology Published 4 December 2023 Crick labs/ facilitiesMaximiliano GutierrezLight MicroscopyHuman Embryonic Stem CellFull details
ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages Authors (9)Beren AylanElliott BernardEnrica PellegrinoLaure BotellaTony FearnsNatalia AthanasiadiClaudio BussiPierre SantucciMaximiliano Gutierrez Nature Microbiology Published 1 May 2023 Crick labs/ facilitiesMaximiliano GutierrezLight MicroscopyHuman Embryonic Stem CellElectron MicroscopyFull details
A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages Authors (23) Melissa Bedard Sanne van der NietElliott Bernard Gregory Babunovic Tan-Yun ChengBeren Aylan[...] Joseph Keane Sho YamasakiMaximiliano Gutierrez Nicole van der Wel D Branch Moody Journal of Clinical Investigation Published 15 March 2023 Crick labsMaximiliano GutierrezFull details
High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages Authors (4)Beren AylanLaure BotellaMaximiliano GutierrezPierre Santucci FEBS Open Bio Published 1 July 2023 Crick labs/ facilitiesMaximiliano GutierrezLight MicroscopyFull details
Visualizing pyrazinamide action by live single-cell imaging of phagosome acidification and Mycobacterium tuberculosis pH homeostasis Authors (8)Pierre SantucciBeren AylanLaure BotellaElliott BernardClaudio BussiEnrica PellegrinoNatalia AthanasiadiMaximiliano Gutierrez mBio Published 1 April 2022 Crick labsMaximiliano GutierrezFull details
Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation Authors (15)Christophe QuevalTony FearnsLaure Botella Alicia Smyth Laura Schnettger Morgane Mitermite[...] Matthias Trost Dirk Werling Francisco J Salguero Stephen V GordonMaximiliano Gutierrez PLOS Pathogens Published 15 March 2021 Crick labs/ facilitiesMaximiliano GutierrezLight MicroscopyElectron MicroscopyFull details
An NAD+ phosphorylase toxin triggers Mycobacterium tuberculosis cell death Authors (23) Diana Mendes Freire Claude GutierrezAcely Garza-Garcia Anna D Grabowska Ambre J Sala Kanchiyaphat Ariyachaokun[...] Pierre GenevauxLuiz Pedro Carvalho Matthias Wilmanns Annabel HA Parret Olivier Neyrolles Molecular Cell Published 18 February 2019 Crick labs/ facilitiesLuiz Pedro CarvalhoMRC Biomedical NMR CentreFull details