I am scientist with a deep interest in understanding how macromolecular interactions regulate complex biological events. My unique preparation and working experience have been pivotal to develop my broad scientific interests, spanning from physical chemistry and structural biology to molecular biology and biochemistry.
I obtained a degree in Chemistry from the University of Naples, “Federico II” (Italy); there I also obtained my PhD in physical chemistry in 2009. During my PhD, I worked on the biophysical and structural characterization of DNA quadruplex assemblies and their ability to bind small molecules of pharmaceutical interest.
After my PhD, at the beginning of 2010, I was awarded a long term EMBO fellowship, which I spent in Prof Maria R Conte’s group at the Randall Division of Cell and Molecular Biophysics, King’s College London. Here, I studied the structure and the function of RNA binding proteins with important roles in mRNA translation and regulation.
At the end of 2012, I became a Research Fellow at the MRC National Institute for Medical Research-London, today known as The Francis Crick Institute, in Dr Katrin Rittinger’s group. Here, I work on the structural characterization of receptors and E3 ubiquitin ligases, involved in regulating the innate immune system.