
Luiz Pedro Carvalho
- Lab: Mycobacterial Metabolism and Antibiotic Research Laboratory
- Job Title: Group Leader
- Email Address:
- Phone Number: +44 (0)20 3796 2300
Related links
Qualifications and history
- 1994-1999 BSc UFRGS, Porto Alegre, Brazil
- 2000-2001 MSc UFRGS, Porto Alegre, Brazil
- 2001-2006 PhD Albert Einstein College of Medicine, New York, USA
- 2006-2011 Postdoctoral fellow Weill Cornell Medical College, New York, USA
- 2011-2015 Group Leader at MRC National Institute for Medical Research, London, UK
- 2015-current Group Leader, the Francis Crick Institute, London, UK
Luiz was born and grew up in the south of Brazil and obtained undergraduate (pharmacy) and MSc (cell and molecular biology) degrees from UFRGS. He then moved to the USA to pursue his PhD studies in the laboratory of John S. Blanchard at the Biochemistry Department of the Albert Einstein College of Medicine in New York. He studied mechanistic enzymology, inhibition kinetics and protein chemistry.
For postdoctoral training Luiz joined Carl Nathan's laboratory at the Weill Cornell Medical College (2006-2011) in New York, exploring the use of rational approaches to antibiotic research and studying Mycobacterium tuberculosis and its interaction with the host. In addition to antibiotic research, Luiz contributed to the first applications of LC-MS-based metabolomics methods for functional genomics and system-level studies of M. tuberculosis, under guidance of Kyu Y. Rhee, also at Cornell.
In 2011 Luiz moved to the Medical Research Council (MRC) National Institute for Medical Research (now part of the Francis Crick Institute) to establish his laboratory working on how Mtb enzymes work, how they are inhibited by antibiotics and how they are organised together to form M. tuberculosis metabolic network. Luiz has been awarded an MRC Centenary Award and the 2014 ASM - Merck Irving S. Sigal Award.
Year published
Research topics
- Biochemistry & Proteomics (26)
- Cell Biology (4)
- Cell Cycle & Chromosomes (2)
- Chemical Biology & High Throughput (6)
- Computational & Systems Biology (26)
- Developmental Biology (1)
- Gene Expression (3)
- Genetics & Genomics (26)
- Genome Integrity & Repair (3)
- Human Biology & Physiology (1)
- Imaging (2)
- Immunology (3)
- Infectious Disease (26)
- Metabolism (26)
- Microfabrication & Bioengineering (1)
- Model Organisms (5)
- Neurosciences (1)
- Signalling & Oncogenes (2)
- Stem Cells (1)
- Structural Biology & Biophysics (26)
- Synthetic Biology (1)
- Tumour Biology (2)
Crick Pre-Crick
Journal
- ACS Infectious Diseases (1)
- ACS Medicinal Chemistry Letters (1)
- Antimicrobial Agents and Chemotherapy (1)
- Biochemical Journal (1)
- Biochemistry (4)
- Bioorganic & Medicinal Chemistry (1)
- Bioorganic & Medicinal Chemistry Letters (1)
- Chemistry & Biology (3)
- ChemistryOpen (1)
- eLife (1)
- EMBO Reports (1)
- FEBS Journal (1)
- Frontiers in Molecular Biosciences (1)
- Journal of Bacteriology (1)
- Journal of Biological Chemistry (2)
- Journal of Experimental Medicine (1)
- Journal of Medicinal Chemistry (3)
- Methods in Molecular Biology (1)
- Microbiology (1)
- Molecular Cell (1)
- Molecular Microbiology (2)
- Nature (1)
- Nature Chemical Biology (2)
- Nature Communications (4)
- PLOS Pathogens (2)
- Proceedings of the National Academy of Sciences of the United States of America (2)
- Structure (1)
- The Lancet (1)
- Tuberculosis (1)