Mary Wu

Antibody correlates of protection against Delta infection after vaccination: a nested case-control within the UK-based SIREN study

Authors (16)

Ana Atti
Ferdinando Insalata
Edward J Carr
Ashley D Otter
Sarah Foulkes
Mary Wu
[...]
Susan Hopkins
Andre Charlett
Rupert Beale
Victoria Hall
SIREN Study Group

Journal of Infection

Published 7 September 2023

Crick labs

Rupert Beale

Full details

CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study

Authors (31)

Isabel Neale
Mohammad Ali
Barbara Kronsteiner
Stephanie Longet
Priyanka Abraham
Alexandra S Deeks
[...]
Miles Carroll
Teresa Lambe
Paul Klenerman
Susanna Dunachie
PITCH Consortium

mBio

Published 1 September 2023

Crick labs

Rupert Beale

Full details

Commercial immunoglobulin products contain neutralising antibodies against SARS-CoV-2 spike protein

Authors (29)

Vinit Upasani
Katie Townsend
Mary Wu
Edward J Carr
Agnieszka Hobbs
Giulia Dowgier
[...]
Rupert Beale
Sonia Gandhi
Emma C Wall
Laura McCoy
David M Lowe

Clinical Infectious Diseases

Published 20 June 2023

Crick labs

Full details

Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London

Authors (54)

Chris Bailey
Theo Sanderson
Hermaleigh Townsley
Jacki Goldman
James RM Black
George Young
[...]
Jerome Nicod
Sonia Gandhi
David LV Bauer
Emma C Wall
Charles Swanton

The Lancet

Published 1 July 2023

Crick labs/ facilities

Full details

Neutralising immunity to omicron sublineages BQ.1.1, XBB, and XBB.1.5 in healthy adults is boosted by bivalent BA.1-containing mRNA vaccination and previous Omicron infection

Authors (36)

Edward J Carr
Mary Wu
Joshua Gahir
Ruth Harvey
Hermaleigh Townsley
Chris Bailey
[...]
Charles Swanton
Sonia Gandhi
David LV Bauer
Emma C Wall
Crick COVID Serology Consortium

Lancet Infectious Diseases

Published 1 July 2023

Crick labs/ facilities

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Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer

Authors (67)

Mary Wu
Scott Shepherd
Annika Fendler
Edward J Carr
Lewis Au
Ruth Harvey
[...]
Emma Nicholson
James Larkin
Emma C Wall
Samra Turajlic
CAPTURE consortium

Cancer Cell

Published 8 May 2023

Crick labs/ facilities

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Strong peak immunogenicity but rapid antibody waning following third vaccine dose in older residents of care homes

Authors (68)

G Tut
T Lancaster
M Krutikov
P Sylla
D Bone
E Spalkova
[...]
A Irwin-Singer
A Hayward
A Copas
L Shallcross
P Moss

Nature Aging

Published 1 January 2023

Crick labs/ facilities

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WHO's therapeutics and COVID-19 living guideline on mAbs needs to be reassessed

Authors (19)

Mary Wu
Edward J Carr
Ruth Harvey
Harriet Mears
Svend Kjaer
Hermaleigh Townsley
[...]
Bryan Williams
Sonia Gandhi
Charles Swanton
Emma C Wall
David LV Bauer

The Lancet

Published 17 December 2022

Crick labs/ facilities

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Functional immune responses against SARS-CoV-2 variants of concern after fourth COVID-19 vaccine dose or infection in patients with blood cancer

Authors (64)

Annika Fendler
Scott Shepherd
Lewis Au
Mary Wu
Ruth Harvey
Katalin Wilkinson
[...]
Emma Nicholson
Susanna Walker
Robert Wilkinson
James Larkin
Samra Turajlic

Cell Reports Medicine

Published 18 October 2022

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Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: a nested case-control within the SIREN study

Authors (37)

Ana Atti
Ferdinando Insalata
Edward J Carr
Ashley D Otter
Javier Castillo-Olivares
Mary Wu
[...]
Susan Hopkins
Tim Brooks
Victoria Hall
The SIREN Study Group
The Crick COVID Immunity Pipeline Consortium

Journal of Infection

Published 1 November 2022

Crick labs/ facilities

Full details

USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer

Authors (19)

Jessica Nelson
May Zaw Thin
Theo Evan
Steven Howell
Mary Wu
Bruna Coelho Almeida
[...]
Bram Snijders
Andreas Prachalias
Yoh Zen
Debashis Sarker
Axel Behrens

Nature Communications

Published 19 April 2022

Crick labs/ facilities

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Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance

Authors (19)

Jason SL Yu
Clara Correia-Melo
Francisco Zorrilla
Lucia Herrera-Dominguez
Mary Wu
Johannes Hartl
[...]
Michael Howell
Judith Berman
Kiran R Patil
Mohammad Tauqeer Alam
Markus Ralser

Nature Microbiology

Published 1 April 2022

Crick labs/ facilities

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Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer

Authors (62)

Annika Fendler
Scott Shepherd
Lewis Au
Mary Wu
Ruth Harvey
Andreas M Schmitt
[...]
Emma Nicholson
Susanna Walker
James Larkin
Samra Turajlic
The CAPTURE consortium

The Lancet

Published 5 March 2022

Crick labs/ facilities

Full details

Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients

Authors (19)

Edward J Carr
Mary Wu
Ruth Harvey
Roseanne E Billany
Emma C Wall
Gavin Kelly
[...]
Rachel B Jones
Rona M Smith
Stephen McAdoo
Michelle Willicombe
Rupert Beale

The Lancet

Published 26 February 2022

Crick labs/ facilities

Full details

Three-dose vaccination elicits neutralising antibodies against omicron

Authors (26)

Mary Wu
Emma C Wall
Edward J Carr
Ruth Harvey
Hermaleigh Townsley
Harriet Mears
[...]
Vincenzo Libri
Bryan Williams
Sonia Gandhi
Charles Swanton
David LV Bauer

The Lancet

Published 19 February 2022

Crick labs/ facilities

Full details

Functional profiling of long intergenic non-coding RNAs in fission yeast

Authors (15)

Maria Rodriguez-Lopez
Shajahan Anver
Cristina Cotobal
Stephan Kamrad
Michal Malecki
Clara Correia-Melo
[...]
Mary Wu
Luis Montemayor
Michael Howell
Markus Ralser
Jürg Bähler

eLife

Published 5 January 2022

Crick labs/ facilities

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Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer

Authors (65)

Annika Fendler
Scott Shepherd
Lewis Au
Katalin Wilkinson
Mary Wu
Andreas M Schmitt
[...]
Susanna Walker
Robert Wilkinson
James Larkin
Samra Turajlic
CAPTURE consortium

Cancer Cell

Published 14 February 2022

Crick labs/ facilities

Full details

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

Authors (98)

Nature Cancer

Published 1 December 2021

Crick labs/ facilities

Full details

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

Authors (98)

Nature Cancer

Published 1 December 2021

Crick labs/ facilities

Full details

Research case studies

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Cut + Paste exhibition

From local to global: preparing for the next pandemic

About us

Mary Wu

PRINCIPAL LABORATORY RESEARCH SCIENTIST

High Throughput Screening

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Crick Pre-Crick

Antibody correlates of protection against Delta infection after vaccination: a nested case-control within the UK-based SIREN study

CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study

Commercial immunoglobulin products contain neutralising antibodies against SARS-CoV-2 spike protein

Independent SARS-CoV-2 staff testing protected academic and health-care institutions in northwest London

Neutralising immunity to omicron sublineages BQ.1.1, XBB, and XBB.1.5 in healthy adults is boosted by bivalent BA.1-containing mRNA vaccination and previous Omicron infection

Sotrovimab restores neutralization against current Omicron subvariants in patients with blood cancer

Strong peak immunogenicity but rapid antibody waning following third vaccine dose in older residents of care homes

WHO's therapeutics and COVID-19 living guideline on mAbs needs to be reassessed

Functional immune responses against SARS-CoV-2 variants of concern after fourth COVID-19 vaccine dose or infection in patients with blood cancer

Antibody correlates of protection from SARS-CoV-2 reinfection prior to vaccination: a nested case-control within the SIREN study

SARS-CoV-2 S2-targeted vaccination elicits broadly neutralizing antibodies

USP25 promotes pathological HIF-1-driven metabolic reprogramming and is a potential therapeutic target in pancreatic cancer

Microbial communities form rich extracellular metabolomes that foster metabolic interactions and promote drug tolerance

Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer

Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients

Three-dose vaccination elicits neutralising antibodies against omicron

Functional profiling of long intergenic non-coding RNAs in fission yeast

Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study

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