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Breadcrumb Research A Z researchers Matt Newton VISITING SCIENTIST Boulton lab DSB Repair Metabolism Laboratory Email Address: Email Year published2023 (1)2022 (2)2021 (2) Facet Year publishedResearch topicsBiochemistry & Proteomics (5)Cell Biology (5)Cell Cycle & Chromosomes (5)Chemical Biology & High Throughput (1)Genetics & Genomics (5)Genome Integrity & Repair (5)Imaging (1)Microfabrication & Bioengineering (1)Model Organisms (5)Structural Biology & Biophysics (1) Facet Research topicsPublication typeJournal article (5)Method (1)Primary research (4) Facet Publication typeJournalMolecular Cell (2)Nature (1)Nature Communications (1)STAR Protocols (1) Facet JournalCrick Pre-CrickCrick publications (5) Facet Crick Pre-Crick Displaying 1 - 5 of 5Last updated : 08 December 2023 03:08 Negative DNA supercoiling induces genome-wide Cas9 off-target activity Authors (13)Matt Newton Marialucrezia Losito Quentin M SmithVenkata Nishita Mohan Parnandi Benjamin J Taylor Pinar Akcakaya[...] Simon H ReedSimon Boulton Graeme A King Maria Emanuela Cuomo David S Rueda Molecular Cell Published 5 October 2023 Crick labsSimon BoultonFull details Search and processing of Holliday junctions within long DNA by junction-resolving enzymes Authors (6) Artur P Kaczmarczyk Anne-Cécile DéclaisMatt NewtonSimon Boulton David MJ Lilley David S Rueda Nature Communications Published 7 October 2022 Crick labsSimon BoultonFull details HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51 Authors (10)Roopesh Anand Erika BuechelmaierOndrej BelanMatt NewtonAleksandra Vancevska Artur KaczmarczykTohru Takaki David S Rueda Simon N PowellSimon Boulton Nature Published 13 January 2022 Crick labsSimon BoultonFull details Generation of versatile ss-dsDNA hybrid substrates for single-molecule analysis Authors (7)Ondrej Belan George Moore Artur KaczmarczykMatt NewtonRoopesh AnandSimon Boulton David S Rueda STAR Protocols Published 18 June 2021 Crick labsSimon BoultonFull details Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins Authors (12)Ondrej Belan Consuelo Barroso Artur KaczmarczykRoopesh AnandStefania FedericoNicola O'Reilly[...]Erik MaeotsRadoslav Enchev Enrique Martinez-Perez David S RuedaSimon Boulton Molecular Cell Published 4 March 2021 Crick labs/ facilitiesRadoslav EnchevSimon BoultonFermentationFull details
Negative DNA supercoiling induces genome-wide Cas9 off-target activity Authors (13)Matt Newton Marialucrezia Losito Quentin M SmithVenkata Nishita Mohan Parnandi Benjamin J Taylor Pinar Akcakaya[...] Simon H ReedSimon Boulton Graeme A King Maria Emanuela Cuomo David S Rueda Molecular Cell Published 5 October 2023 Crick labsSimon BoultonFull details
Search and processing of Holliday junctions within long DNA by junction-resolving enzymes Authors (6) Artur P Kaczmarczyk Anne-Cécile DéclaisMatt NewtonSimon Boulton David MJ Lilley David S Rueda Nature Communications Published 7 October 2022 Crick labsSimon BoultonFull details
HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51 Authors (10)Roopesh Anand Erika BuechelmaierOndrej BelanMatt NewtonAleksandra Vancevska Artur KaczmarczykTohru Takaki David S Rueda Simon N PowellSimon Boulton Nature Published 13 January 2022 Crick labsSimon BoultonFull details
Generation of versatile ss-dsDNA hybrid substrates for single-molecule analysis Authors (7)Ondrej Belan George Moore Artur KaczmarczykMatt NewtonRoopesh AnandSimon Boulton David S Rueda STAR Protocols Published 18 June 2021 Crick labsSimon BoultonFull details
Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins Authors (12)Ondrej Belan Consuelo Barroso Artur KaczmarczykRoopesh AnandStefania FedericoNicola O'Reilly[...]Erik MaeotsRadoslav Enchev Enrique Martinez-Perez David S RuedaSimon Boulton Molecular Cell Published 4 March 2021 Crick labs/ facilitiesRadoslav EnchevSimon BoultonFermentationFull details