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Breadcrumb Research A Z researchers Matthew Cockman Senior Laboratory Research Scientist Ratcliffe lab Hypoxia Biology Laboratory Email Address: Email Phone Number: +44 (0)20 3796 3488 Year published2022 (3)2019 (2)2018 (1) Facet Year publishedResearch topicsBiochemistry & Proteomics (6)Cell Biology (6)Chemical Biology & High Throughput (1)Computational & Systems Biology (1) (-)Metabolism (6)Signalling & Oncogenes (6) Facet Research topicsPublication typeJournal article (6)Primary research (6) Facet Publication typeJournalCardiovascular Research (1)eLife (1)EMBO Reports (1)Journal of Biological Chemistry (1)Nature Chemical Biology (1)Proceedings of the National Academy of Sciences of USA (1) Facet JournalCrick Pre-CrickCrick publications (6) Facet Crick Pre-Crick Displaying 1 - 6 of 6Last updated : 23 April 2024 03:59 Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6 Authors (10)Matthew CockmanYoichiro SugimotoHamish Pegg Norma Masson Eidarus Salah Anthony Tumber Helen R FlynnJoanna Kirkpatrick Christopher J SchofieldPeter Ratcliffe Proceedings of the National Academy of Sciences of USA Published 9 August 2022 Crick labs/ facilitiesPeter RatcliffeProteomicsFull details Factor inhibiting HIF can catalyse two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins Authors (16) Thomas M Leissing Adam P Hardy Hokfung Chan Yihua Wang Anthony Tumber Rasheduzzaman Chowdhury[...] Roman Fischer Benedikt M KesslerPeter Ratcliffe Xin Lu Christopher J Schofield Journal of Biological Chemistry Published 1 June 2022 Crick labsPeter RatcliffeFull details Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischaemia-reperfusion injury Authors (11) Michael Harris Junhui Sun Karen Keeran Angel Aponte Komudi Singh Danielle Springer Marjan Gucek Mehdi PiroozniaMatthew Cockman Elizabeth Murphy Leslie M Kennedy Cardiovascular Research Published 1 September 2022 Crick labsPeter RatcliffeFull details Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates Authors (11)Matthew Cockman Kerstin Lippl Ya-Min TianHamish Pegg William D Figg Martine I Abboud Raphael Heilig Roman Fischer Johanna Myllyharju Christopher J SchofieldPeter Ratcliffe eLife Published 10 September 2019 Crick labs/ facilitiesPeter RatcliffeProteomicsFull details Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin Authors (11) James A Smythies Min Sun Norma Masson Rafik Salama Peter D Simpson Elizabeth Murray Viviana NeumannMatthew Cockman Hani ChoudhryPeter Ratcliffe David R Mole EMBO Reports Published 1 January 2019 Crick labsPeter RatcliffeFull details The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases Authors (23) Suzana Markolovic Qinqin Zhuang Sarah E Wilkins Charlotte D Eaton Martine I Abboud Maximiliano J Katz[...] Roman Fischer Pablo Wappner Rasheduzzaman Chowdhury Mathew L Coleman Christopher J Schofield Nature Chemical Biology Published 18 June 2018 Crick labsKaren VousdenPeter RatcliffeFull details
Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6 Authors (10)Matthew CockmanYoichiro SugimotoHamish Pegg Norma Masson Eidarus Salah Anthony Tumber Helen R FlynnJoanna Kirkpatrick Christopher J SchofieldPeter Ratcliffe Proceedings of the National Academy of Sciences of USA Published 9 August 2022 Crick labs/ facilitiesPeter RatcliffeProteomicsFull details
Factor inhibiting HIF can catalyse two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins Authors (16) Thomas M Leissing Adam P Hardy Hokfung Chan Yihua Wang Anthony Tumber Rasheduzzaman Chowdhury[...] Roman Fischer Benedikt M KesslerPeter Ratcliffe Xin Lu Christopher J Schofield Journal of Biological Chemistry Published 1 June 2022 Crick labsPeter RatcliffeFull details
Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischaemia-reperfusion injury Authors (11) Michael Harris Junhui Sun Karen Keeran Angel Aponte Komudi Singh Danielle Springer Marjan Gucek Mehdi PiroozniaMatthew Cockman Elizabeth Murphy Leslie M Kennedy Cardiovascular Research Published 1 September 2022 Crick labsPeter RatcliffeFull details
Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates Authors (11)Matthew Cockman Kerstin Lippl Ya-Min TianHamish Pegg William D Figg Martine I Abboud Raphael Heilig Roman Fischer Johanna Myllyharju Christopher J SchofieldPeter Ratcliffe eLife Published 10 September 2019 Crick labs/ facilitiesPeter RatcliffeProteomicsFull details
Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin Authors (11) James A Smythies Min Sun Norma Masson Rafik Salama Peter D Simpson Elizabeth Murray Viviana NeumannMatthew Cockman Hani ChoudhryPeter Ratcliffe David R Mole EMBO Reports Published 1 January 2019 Crick labsPeter RatcliffeFull details
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases Authors (23) Suzana Markolovic Qinqin Zhuang Sarah E Wilkins Charlotte D Eaton Martine I Abboud Maximiliano J Katz[...] Roman Fischer Pablo Wappner Rasheduzzaman Chowdhury Mathew L Coleman Christopher J Schofield Nature Chemical Biology Published 18 June 2018 Crick labsKaren VousdenPeter RatcliffeFull details