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Breadcrumb Research A-Z researchers Mika Kintzel PHD Student Hess lab Biological Inorganic Chemistry Laboratory Email Address: Crick email Email Year published 2026 (4) 2025 (1) Facet Year published Research topics Biochemistry & Proteomics (3) Chemical Biology & High Throughput (3) Facet Research topics Crick Pre-Crick Crick publications (5) Facet Crick Pre-Crick Publication type Journal article (3) Preprint (2) Primary research (3) Facet Publication type Journal Angewandte Chemie (1) Angewandte Chemie International Edition (1) chemRxiv (2) Journal of the American Chemical Society (1) Facet Journal Displaying 1 - 5 of 5Last updated : 15 August 2026 02:08 Expanding metal complex enzyme inhibitor discovery through high-throughput virtual screening Preprint Authors (15) Mika Kintzel Yew Mun Yip Daniella Hares Jonathan Bailey Alain Oregioni Sarah Maslen [...] Marcus Fischer Mark Skehel Geoff Kelly Joanna Redmond Jeannine Hess chemRxiv Published 15 July 2026 Crick labs/ facilities Jeannine Hess Structural Biology Proteomics MRC Biomedical NMR Centre Chemical Biology Full details Proteome-wide target identification using reactive metallo-scaffolds (r-mS): A platform for metallodrug discovery Authors (16) Jessica Waters Harry Wilders George S Biggs Mika Kintzel Emma E Cawood Jonathan Bailey [...] Joanna Redmond Mark Skehel David House Jacob Bush Jeannine Hess Angewandte Chemie International Edition Published 10 July 2026 Crick labs/ facilities Jeannine Hess Proteomics Chemical Biology Full details Proteome‐wide target identification using reactive metallo‐scaffolds (r‐mS): A platform for metallodrug discovery Authors (16) Jessica Waters Harry Wilders George S Biggs Mika Kintzel Emma E Cawood Jonathan Bailey [...] Joanna Redmond Mark Skehel David House Jacob Bush Jeannine Hess Angewandte Chemie Published 10 July 2026 Crick labs/ facilities Jeannine Hess Proteomics Chemical Biology Full details Rationally designed ruthenium(II) complexes combat drug resistance in Staphylococcus aureus via type IIA topoisomerase inhibition Preprint Authors (24) Blake Ho Thomas Rees Mollie A Phillips Enkai Jin Evangelos Christodoulou Andrew G Purkiss [...] Michael Howell J Mark Sutton Svend Kjaer Dimitrios Evangelopoulos Jeannine Hess chemRxiv Published 1 April 2026 Crick labs/ facilities Jeannine Hess Structural Biology Screening and Automated Science Chemical Biology Bioinformatics and Biostatistics Genomics Full details Light-activated metal-dependent protein degradation: A heterobifunctional ruthenium(II) photosensitizer targeting New Delhi metallo-β-lactamase 1 Authors (23) Lars Stevens-Cullinane Thomas Rees Calum Evans Blake Ho Mika Kintzel Yew Mun Yip [...] Mark Skehel Manuel M Müller Eachan Johnson Maxie M Roessler Jeannine Hess Journal of the American Chemical Society Published 10 December 2025 Crick labs/ facilities Eachan Johnson Jeannine Hess Structural Biology Proteomics Screening and Automated Science Chemical Biology Full details
Expanding metal complex enzyme inhibitor discovery through high-throughput virtual screening Preprint Authors (15) Mika Kintzel Yew Mun Yip Daniella Hares Jonathan Bailey Alain Oregioni Sarah Maslen [...] Marcus Fischer Mark Skehel Geoff Kelly Joanna Redmond Jeannine Hess chemRxiv Published 15 July 2026 Crick labs/ facilities Jeannine Hess Structural Biology Proteomics MRC Biomedical NMR Centre Chemical Biology Full details
Proteome-wide target identification using reactive metallo-scaffolds (r-mS): A platform for metallodrug discovery Authors (16) Jessica Waters Harry Wilders George S Biggs Mika Kintzel Emma E Cawood Jonathan Bailey [...] Joanna Redmond Mark Skehel David House Jacob Bush Jeannine Hess Angewandte Chemie International Edition Published 10 July 2026 Crick labs/ facilities Jeannine Hess Proteomics Chemical Biology Full details
Proteome‐wide target identification using reactive metallo‐scaffolds (r‐mS): A platform for metallodrug discovery Authors (16) Jessica Waters Harry Wilders George S Biggs Mika Kintzel Emma E Cawood Jonathan Bailey [...] Joanna Redmond Mark Skehel David House Jacob Bush Jeannine Hess Angewandte Chemie Published 10 July 2026 Crick labs/ facilities Jeannine Hess Proteomics Chemical Biology Full details
Rationally designed ruthenium(II) complexes combat drug resistance in Staphylococcus aureus via type IIA topoisomerase inhibition Preprint Authors (24) Blake Ho Thomas Rees Mollie A Phillips Enkai Jin Evangelos Christodoulou Andrew G Purkiss [...] Michael Howell J Mark Sutton Svend Kjaer Dimitrios Evangelopoulos Jeannine Hess chemRxiv Published 1 April 2026 Crick labs/ facilities Jeannine Hess Structural Biology Screening and Automated Science Chemical Biology Bioinformatics and Biostatistics Genomics Full details
Light-activated metal-dependent protein degradation: A heterobifunctional ruthenium(II) photosensitizer targeting New Delhi metallo-β-lactamase 1 Authors (23) Lars Stevens-Cullinane Thomas Rees Calum Evans Blake Ho Mika Kintzel Yew Mun Yip [...] Mark Skehel Manuel M Müller Eachan Johnson Maxie M Roessler Jeannine Hess Journal of the American Chemical Society Published 10 December 2025 Crick labs/ facilities Eachan Johnson Jeannine Hess Structural Biology Proteomics Screening and Automated Science Chemical Biology Full details
