Mike studied pre-clinical medicine at King's College, Cambridge, and then completed his clinical studies at University College London.
After a period of postgraduate clinical training in London, he joined John Hardy's lab at UCL, to develop human stem cell models of Parkinson's disease. This included a year spent in Tilo Kunath's lab at the Institute of Stem Cell Research (now the MRC Centre for Regenerative Medicine) in Edinburgh.
Following completion of specialist clinical training in Neurology in London, he carried out postdoctoral work in Josef Kittler's lab at UCL, researching mitochondrial and synaptic dysfunction in Parkinson's disease.
He has recently been appointed as a clinical group leader at the Crick, to establish a new group examining the interaction between mitochondria and neuronal synapses, and how this can be disrupted in neurological and psychiatric disease. As a clinician, he sees patients at the National Hospital for Neurology and Neurosurgery, and University College Hospital.