Following a degree in natural sciences at Jesus College, University of Cambridge (1993-1996), Nick studied for a PhD with Janet Thornton at UCL (University College London) (1996-2000) on the basis for specificity of DNA-binding proteins. He then moved to Yale University, USA, as an Anna Fuller Postdoctoral Fellow with Mark Gerstein (2000-2005), where he shifted research focus to genomics with a particular emphasis on yeast transcriptional regulation.
He was a Group Leader at the EMBL-European Bioinformatics Institute (2005-2012) in Cambridge and built a computational biology laboratory with an emphasis on genomics and gene regulation. During this time, he joined the Okinawa Institute of Science & Technology as an Adjunct Faculty to establish a small group focused on developmental regulation (2011-present).
He recently returned to UCL as a Chair in Computational Biology in the UCL Genetics Institute and holds a joint appointment as a Senior Winton Group Leader at the Francis Crick Institute, in recognition of the Winton Charitable Foundation's generous donation towards establishing the Francis Crick Institute. Nick was elected as an EMBO Member in 2013.