Nicholas Owen

VISITING SCIENTIST

Moosajee lab

Ocular Genomics and Therapeutics Laboratory

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Displaying 1 - 11 of 11

Last updated : 30 September 2023 02:08

Identification of novel coloboma candidate genes through conserved gene expression analyses across four vertebrate species

Authors (7)

Violeta Trejo-Reveles
Nicholas Owen
Brian Ho Ching Chan
Maria Toms
Jeffrey J Schoenebeck
Mariya Moosajee
Joe Rainger

Biomolecules

Published 4 February 2023

Crick labs

Mariya Moosajee

Full details

Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina

Authors (10)

Nicholas Owen
Maria Toms
Yuan Tian
Lyes Toualbi
Rose Richardson
Rodrigo Young
Dhani Tracey-White
Pawan Dhami
Stephan Beck
Mariya Moosajee

Journal of Pathology

Published 1 April 2023

Crick labs

Mariya Moosajee

Full details

Identification of 4 novel human ocular coloboma genes ANK3, BMPR1B, PDGFRA, and CDH4 through evolutionary conserved vertebrate gene analysis

Authors (8)

Nicholas Owen
Maria Toms
Rodrigo M Young
Jonathan Eintracht
Hajrah Sarkar
Brian P Brooks
Mariya Moosajee
Genomics England Research Consortium

Genetics in Medicine

Published 1 May 2022

Crick labs

Mariya Moosajee

Full details

REP1-deficiency causes systemic dysfunction of lipid metabolism and oxidative stress in choroideremia

Authors (11)

Dulce Lima Cunha
Rose Richardson
Dhani Tracey-White
Alessandro Abbouda
Andreas Mitsios
Verena Horneffer-van der Sluis
Panteleimon Takis
Nicholas Owen
Jane Skinner
Ailsa A Welch
Mariya Moosajee

JCI insight

Published 22 April 2021

Crick labs

Mariya Moosajee

Full details

EPHA2 segregates with microphthalmia and congenital cataracts in two unrelated families

Authors (7)

Philippa Harding
Maria Toms
Elena Schiff
Nicholas Owen
Suzannah Bell
Ian Christopher Lloyd
Mariya Moosajee

International Journal of Molecular Sciences

Published 22 February 2021

Crick labs

Mariya Moosajee

Full details

Ocular phenotype associated with DYRK1A variants

Authors (4)

Genes (Basel)

Published 5 February 2021

Crick labs

Mariya Moosajee

Full details

From transcriptomics to treatment in inherited optic neuropathies

Authors (4)

Michael James Gilhooley
Nicholas Owen
Mariya Moosajee
Patrick Yu Wai Man

Genes

Published 22 January 2021

Crick labs

Mariya Moosajee

Full details

PAX6 missense variants in two families with isolated foveal hypoplasia and nystagmus: evidence of paternal postzygotic mosaicism

Authors (6)

Dulce Lima Cunha
Nicholas Owen
Vijay Tailor
Marta Corton
Maria Theodorou
Mariya Moosajee

European Journal of Human Genetics

Published 1 February 2021

Crick labs

Mariya Moosajee

Full details

RNA-sequencing in ophthalmology research: considerations for experimental design and analysis

Authors (2)

Therapeutic Advances in Ophthalmology

Published 15 March 2019

Crick labs

Mariya Moosajee

Full details

Transcriptome profiling of zebrafish optic fissure fusion

Authors (6)

R Richardson
Nicholas Owen
M Toms
Rodrigo M Young
D Tracey-White
Mariya Moosajee

Scientific Reports

Published 7 February 2019

Crick labs

Mariya Moosajee

Full details

Nonsyndromic retinal dystrophy due to bi-allelic mutations in the ciliary transport gene IFT140

Authors (18)

Sarah Hull
Nicholas Owen
Farrah Islam
Dhani Tracey-White
Vincent Plagnol
Graham E Holder
[...]
Ajoy Sarkar
Mariya Moosajee
Andrew R Webster
Gavin Arno
Anthony T Moore

Investigative Ophthalmology and Visual Science

Published 1 March 2016

Crick labs

Mariya Moosajee

Full details

Research case studies

Vacancies

Cut + Paste exhibition

From local to global: preparing for the next pandemic

About us

Nicholas Owen

VISITING SCIENTIST

Moosajee lab

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Identification of novel coloboma candidate genes through conserved gene expression analyses across four vertebrate species

Loss of the crumbs cell polarity complex disrupts epigenetic transcriptional control and cell cycle progression in the developing retina

Identification of 4 novel human ocular coloboma genes ANK3, BMPR1B, PDGFRA, and CDH4 through evolutionary conserved vertebrate gene analysis

REP1-deficiency causes systemic dysfunction of lipid metabolism and oxidative stress in choroideremia

EPHA2 segregates with microphthalmia and congenital cataracts in two unrelated families

Ocular phenotype associated with DYRK1A variants

From transcriptomics to treatment in inherited optic neuropathies

PAX6 missense variants in two families with isolated foveal hypoplasia and nystagmus: evidence of paternal postzygotic mosaicism

RNA-sequencing in ophthalmology research: considerations for experimental design and analysis

Transcriptome profiling of zebrafish optic fissure fusion

Nonsyndromic retinal dystrophy due to bi-allelic mutations in the ciliary transport gene IFT140

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