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Breadcrumb Research A-Z researchers Oliver Acton Affiliated Researcher Taylor lab Macromolecular Structure Laboratory Email Address: Crick email Email Phone Number: Crick phone +442037962364 Year published 2024 (13) 2019 (1) Facet Year published Research topics Cell Biology (1) Ecology,Evolution & Ethology (1) Genetics & Genomics (1) Genome Integrity & Repair (1) Imaging (1) Infectious Disease (1) Metabolism (1) Model Organisms (1) Structural Biology & Biophysics (2) Facet Research topics Crick Pre-Crick Crick publications (14) Facet Crick Pre-Crick Publication type Dataset (12) Journal article (2) Primary research (2) Facet Publication type Journal EMBO Molecular Medicine (12) Nature Communications (2) Facet Journal Displaying 1 - 14 of 14Last updated : 08 August 2026 02:57 EMDB entry EMD-18729: Cryo-EM structure of tetrameric human SAMHD1 with dApNHpp Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details EMDB entry EMD-18730: Cryo-EM structure of tetrameric human SAMHD1 State I - Tense Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details EMDB entry EMD-18731: Cryo-EM structure of tetrameric human SAMHD1 State II - Hemi-relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details EMDB entry EMD-18732: Cryo-EM structure of tetrameric human SAMHD1 State III - Relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details EMDB entry EMD-18733: Cryo-EM structure of tetrameric human SAMHD1 State IV - Depleted relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details EMDB entry EMD-18734: Cryo-EM structure of tetrameric human SAMHD1 State V - Depleted relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details PDB entry 8QXJ: Cryo-EM structure of tetrameric human SAMHD1 with dApNHpp Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details PDB entry 8QXK: Cryo-EM structure of tetrameric human SAMHD1 State I - Tense Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details PDB entry 8QXL: Cryo-EM structure of tetrameric human SAMHD1 State II - Hemi-relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details PDB entry 8QXM: Cryo-EM structure of tetrameric human SAMHD1 State III - Relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details PDB entry 8QXN: Cryo-EM structure of tetrameric human SAMHD1 State IV - Depleted relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details PDB entry 8QXO: Cryo-EM structure of tetrameric human SAMHD1 State V - Depleted relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis Authors (10) Oliver Acton Devon Sheppard Simone Kunzelmann Sarah Caswell Andrea Nans Ailidh Burgess Geoff Kelly Liz Morris Peter Rosenthal Ian Taylor Nature Communications Published 6 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details Structural basis for Fullerene geometry in a human endogenous retrovirus capsid Authors (12) Oliver Acton Tim Grant Giuseppe Nicastro Neil J Ball David C Goldstone Laura E Robertson [...] Andrea Nans Andres Ramos Jonathan P Stoye Ian Taylor Peter Rosenthal Nature Communications Published 20 December 2019 Crick labs/ facilities Ian Taylor Jonathan Stoye Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
EMDB entry EMD-18729: Cryo-EM structure of tetrameric human SAMHD1 with dApNHpp Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
EMDB entry EMD-18730: Cryo-EM structure of tetrameric human SAMHD1 State I - Tense Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
EMDB entry EMD-18731: Cryo-EM structure of tetrameric human SAMHD1 State II - Hemi-relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
EMDB entry EMD-18732: Cryo-EM structure of tetrameric human SAMHD1 State III - Relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
EMDB entry EMD-18733: Cryo-EM structure of tetrameric human SAMHD1 State IV - Depleted relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
EMDB entry EMD-18734: Cryo-EM structure of tetrameric human SAMHD1 State V - Depleted relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Electron Microscopy Data Bank (EMDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
PDB entry 8QXJ: Cryo-EM structure of tetrameric human SAMHD1 with dApNHpp Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
PDB entry 8QXK: Cryo-EM structure of tetrameric human SAMHD1 State I - Tense Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
PDB entry 8QXL: Cryo-EM structure of tetrameric human SAMHD1 State II - Hemi-relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
PDB entry 8QXM: Cryo-EM structure of tetrameric human SAMHD1 State III - Relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
PDB entry 8QXN: Cryo-EM structure of tetrameric human SAMHD1 State IV - Depleted relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
PDB entry 8QXO: Cryo-EM structure of tetrameric human SAMHD1 State V - Depleted relaxed Authors (4) Oliver Acton Devon Sheppard Peter Rosenthal Ian Taylor Protein Data Bank (RCSB PDB) Published 15 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis Authors (10) Oliver Acton Devon Sheppard Simone Kunzelmann Sarah Caswell Andrea Nans Ailidh Burgess Geoff Kelly Liz Morris Peter Rosenthal Ian Taylor Nature Communications Published 6 May 2024 Crick labs/ facilities Ian Taylor Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
Structural basis for Fullerene geometry in a human endogenous retrovirus capsid Authors (12) Oliver Acton Tim Grant Giuseppe Nicastro Neil J Ball David C Goldstone Laura E Robertson [...] Andrea Nans Andres Ramos Jonathan P Stoye Ian Taylor Peter Rosenthal Nature Communications Published 20 December 2019 Crick labs/ facilities Ian Taylor Jonathan Stoye Peter Rosenthal Structural Biology MRC Biomedical NMR Centre Full details
