Research case studies Explore a selection of reports that spotlight particular areas of research at the Crick over the past five years.
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Breadcrumb Research A Z researchers Rob Hynds Visiting Scientist Swanton lab Cancer Evolution and Genome Instability Laboratory Email Address: Email Rob is a Sir Henry Wellcome postdoctoral fellow at University College London and The Francis Crick Institute. His expertise are in epithelial stem cell biology and patient-derived cancer models.Year published (-)2021 (2) Facet Year publishedResearch topicsBiochemistry & Proteomics (1)Cell Biology (1)Cell Cycle & Chromosomes (1)Chemical Biology & High Throughput (2)Computational & Systems Biology (2)Genetics & Genomics (2)Genome Integrity & Repair (2)Human Biology & Physiology (2)Immunology (1) (-)Model Organisms (2)Signalling & Oncogenes (2)Tumour Biology (2) Facet Research topicsPublication typeJournal article (2)Primary research (2) Facet Publication typeJournalCancer Cell (1)Cancer Discovery (1) Facet JournalCrick Pre-CrickCrick publications (2) Facet Crick Pre-Crick Displaying 1 - 2 of 2Last updated : 23 April 2024 03:45 Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma Authors (207)Lewis Au Emine Hatipoglu Marc Robert de MassyKevin Litchfield Gordon BeattieAndrew Rowan[...] Jonathon Olsburgh Alexander Polson Sarah Rudman Mary Varia Hema Verma Cancer Cell Published 8 November 2021 Crick labs/ facilitiesSamra TurajlicCharles SwantonGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFull details Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution Authors (47)Mani VenkatesanMihaela Angelova Clare Puttick Haoran ZhaiDeborah CaswellWei-Ting Lu[...] Samuel F Bakhoum Jiri Bartek Nnennaya KanuCharles Swanton TRACERx Consortium Cancer Discovery Published 1 October 2021 Crick labs/ facilitiesCharles SwantonSimon BoultonHigh Throughput ScreeningLight MicroscopyFlow CytometryExperimental HistopathologyCell ServicesAdvanced SequencingFull details
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma Authors (207)Lewis Au Emine Hatipoglu Marc Robert de MassyKevin Litchfield Gordon BeattieAndrew Rowan[...] Jonathon Olsburgh Alexander Polson Sarah Rudman Mary Varia Hema Verma Cancer Cell Published 8 November 2021 Crick labs/ facilitiesSamra TurajlicCharles SwantonGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFull details
Induction of APOBEC3 exacerbates DNA replication stress and chromosomal instability in early breast and lung cancer evolution Authors (47)Mani VenkatesanMihaela Angelova Clare Puttick Haoran ZhaiDeborah CaswellWei-Ting Lu[...] Samuel F Bakhoum Jiri Bartek Nnennaya KanuCharles Swanton TRACERx Consortium Cancer Discovery Published 1 October 2021 Crick labs/ facilitiesCharles SwantonSimon BoultonHigh Throughput ScreeningLight MicroscopyFlow CytometryExperimental HistopathologyCell ServicesAdvanced SequencingFull details